Mixed connective tissue disease

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What is mixed connective tissue disease?

Mixed connective tissue disease is an uncommon autoimmune disorder that causes overlapping features of primarily three connective tissue diseases: lupus, scleroderma and polymyositis. It may be preceded by Raynaud's phenomenon and have features of rheumatoid arthritis.

Common symptoms reported by people with mixed connective tissue disease

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people with mixed connective tissue disease

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Plaquenil)
Type
Prescription Drug
How many have tried
62
Treatment name(s)

(Deltasone)
Type
Prescription Drug
How many have tried
30
Treatment name(s)

(Apo-Methotrexate)
Type
Prescription Drug
How many have tried
22
Treatment name(s)

(Folic Acid Prescription)
Type
Supplement
How many have tried
14
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
10
Treatment name(s)

(Advil)
Type
Over the Counter Drug
How many have tried
10
Treatment name(s)

(Naprosyn)
Type
Prescription Drug
How many have tried
10
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
9
Tried for
Pain (9)
Treatment name(s)

(Mobic)
Type
Prescription Drug
How many have tried
8
Treatment name(s)

(Flexeril)
Type
Prescription Drug
How many have tried
6

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
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Compare treatments taken by people with mixed connective tissue disease

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Plaquenil)
Perceived effectiveness
for mixed connective tissue disease (24 evaluations)
Side effects
nausea blurry vision 29 more
Total evaluations
31
Treatment name(s)

(Deltasone)
Perceived effectiveness
for mixed connective tissue disease (17 evaluations)
Side effects
weight gain headaches 29 more
Total evaluations
27
Treatment name(s)

(Apo-Methotrexate)
Perceived effectiveness
for mixed connective tissue disease (9 evaluations)
Side effects
nausea diarrhea 13 more
Total evaluations
16
Treatment name(s)

(Folic Acid Prescription)
Perceived effectiveness
for mixed connective tissue disease (6 evaluations)
Side effects
Total evaluations
6
Treatment name(s)

(Neurontin)
Perceived effectiveness
for Pain (5 evaluations)
Side effects
drowsiness groggy in morning 1 more
Total evaluations
5
Treatment name(s)

(Advil)
Perceived effectiveness
No evaluations
Side effects
liver damage
Total evaluations
1
Treatment name(s)

(Naprosyn)
Perceived effectiveness
for mixed connective tissue disease (4 evaluations)
Side effects
gastrointestinal (GI) bleeding idiopathic anaphylaxis
Total evaluations
4
Treatment name(s)

(Ultram)
Perceived effectiveness
for Pain (3 evaluations)
Side effects
brain fog constipation 2 more
Total evaluations
3
Tried for
Pain (9)
Treatment name(s)

(Mobic)
Perceived effectiveness
for Pain (3 evaluations)
Side effects
water retention in hands and feet
Total evaluations
3
Treatment name(s)

(Flexeril)
Perceived effectiveness
for Pain (10 evaluations)
Side effects
drowsiness constipation 8 more
Total evaluations
10
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
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Who has mixed connective tissue disease on PatientsLikeMe?


Age
Age Proportion # of patients
<20 8
20s 36
30s 149
40s 289
50s 289
60s 139
70+ 18
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 61
20-29 years 80
30-39 years 130
40-49 years 102
50-59 years 44
60-69 years 10
70+ years 0

Sex

Distribution of sex

96% Female
4% Male

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 500
Not Diagnosed 29

These charts show data from mixed connective tissue disease patients who have completed their condition history
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