What is Modafinil?

Category: Prescription Drugs

Most popular types: Provigil Alertec Modiodal Show all

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Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder or as an adjunctive therapy for obstructive sleep apnea. It may also be used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fatigue 1,534 721
Multiple sclerosis 917 437
Excessive daytime sleepiness (somnolence) 526 367
Narcolepsy 106 57
Brain fog 81 53

Show all 85 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 73
Moderate 157
Mild 262
None 646

Commonly reported side effects and conditions associated with Modafinil

Side effect Patients
Jittery feeling 59
Headaches 56
Dry mouth 51
Anxious mood 36
Tachycardia (fast heart rate) 31
Irritability 22

Show all 148 reported side effects

Dosages

Based on patients currently taking Modafinil

Dosage Patients
200 mg daily 86
100 mg daily 55
400 mg daily 30
200 mg twice daily 18
200mg as needed 10
100 mg twice daily 7
100mg as needed 6
400 mg twice daily 5
150 mg daily 4
300 mg daily 3

See all 29 dosages

Why patients stopped taking Modafinil

Multiple reasons could be selected

Reason Patients
Did not seem to work 291
Other 207
Side effects too severe 200
Expense 182
Doctor's advice 118
Change in health plan coverage 93
Personal research 36
Course of treatment ended 19
See all 887 patients who've stopped taking Modafinil

Duration

Currently taking Modafinil

Duration Patients
Less than 1 month 1
1 - 6 months 13
6 months - 1 year 9
1 - 2 years 14
2 - 5 years 51
5 - 10 years 83
10 years or more 74

Stopped taking Modafinil

Duration Patients
Less than 1 month 132
1 - 6 months 184
6 months - 1 year 128
1 - 2 years 145
2 - 5 years 197
5 - 10 years 78
10 years or more 26
Adherence
Adherence Evaluations
Always 775
Usually 228
Sometimes 98
Never taken as prescribed 37
Burden
Burden Evaluations
Very hard to take 36
Somewhat hard to take 65
A little hard to take 143
Not at all hard to take 894
Cost per month
Cost per month Evaluations
$200+ 89
$100-199 54
$50-99 140
$25-49 166
< $25 337
Not specified 352

What people switch to and from

Patients started taking Modafinil after stopping:

Treatment Patients
Methylphenidate (Ritalin) 26
Armodafinil (Nuvigil) 20
Amphetamine-Dextroamphetamine (Adderall) 16
Amantadine (Symmetrel) 11
Dextroamphetamine (Dexedrine) 2

Show all 16 treatments patients report switching from

Patients stopped taking Modafinil and switched to:

Treatment Patients
Armodafinil (Nuvigil) 33
Amphetamine-Dextroamphetamine (Adderall) 29
Methylphenidate (Ritalin) 10
Dextroamphetamine (Dexedrine) 4
Amantadine (Symmetrel) 2

Show all 9 treatments patients report switching to

Last updated:

133 patient evaluations for Modafinil

Dec 2, 2015 (Started Apr 06, 2006)

  • Effectiveness
    Major (for multiple sclerosis)
  • Effectiveness
    Major (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Provigil gives me energy to do my daily chores i.e. fixing meals, laundry, showering. I have no side efffects! The generic modafinil is the same as Provigil and much less expensive!

  • 0 helpful marks

Jun 26, 2015 (Started Jan 10, 2009)

  • Effectiveness
    Slight (for multiple sclerosis)
  • Effectiveness
    Moderate (for fatigue)
  • Effectiveness
    Major (for brain fog)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Stick to it. Take before noon. It could otherwise keep you awake at night.
Cost: < $25 monthly

Mar 19, 2009 (Started Jan 10, 2009)

  • Effectiveness
    Can't tell (for brain fog)
  • Effectiveness
    None (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Feb 28, 2015 (Started Apr 15, 2012)

  • Effectiveness
    Moderate (for narcolepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 300 mg Daily

Oct 7, 2012 (Started Apr 15, 2012)

  • Effectiveness
    Major (for narcolepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 133 patient evaluations for Modafinil