What is Modafinil?

Category: Prescription Drugs

Most popular types: Provigil Alertec Modiodal Show all

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Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder or as an adjunctive therapy for obstructive sleep apnea. It may also be used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fatigue 1,515 689
Multiple sclerosis 920 427
Excessive daytime sleepiness (somnolence) 501 342
Narcolepsy 101 54
Brain fog 80 49

Show all 93 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
72
Moderate
155
Mild
254
None
613

Commonly reported side effects and conditions associated with Modafinil

Side effect Patients
Jittery feeling 58
Headaches 56
Dry mouth 51
Anxious mood 36
Sleep problems 29
Heart rate increased 26

Show all 178 reported side effects

Dosages

Based on patients currently taking Modafinil

Dosage Patients
200 mg daily 102
100 mg daily 50
400 mg daily 29
200 mg twice daily 19
200mg as needed 13
100mg as needed 10
100 mg twice daily 5
50 mg daily 4
400 mg twice daily 4
150 mg daily 2

See all 27 dosages

Why patients stopped taking Modafinil

Multiple reasons could be selected

Reason Patients
Did not seem to work 281
Other 204
Side effects too severe 197
Expense 182
Doctor's advice 119
Change in health plan coverage 89
Personal research 35
Course of treatment ended 19
See all 871 patients who've stopped taking Modafinil

Duration

Currently taking Modafinil

Duration Patients
Less than 1 month 1
1 - 6 months 15
6 months - 1 year 12
1 - 2 years 23
2 - 5 years 42
5 - 10 years 103
10 years or more 63

Stopped taking Modafinil

Duration Patients
Less than 1 month 120
1 - 6 months 186
6 months - 1 year 128
1 - 2 years 145
2 - 5 years 193
5 - 10 years 76
10 years or more 26
Adherence
Adherence Evaluations
Always 743
Usually 219
Sometimes 96
Never taken as prescribed 36
Burden
Burden Evaluations
Very hard to take 36
Somewhat hard to take 64
A little hard to take 138
Not at all hard to take 856
Cost per month
Cost per month Evaluations
$200+ 88
$100-199 51
$50-99 135
$25-49 159
< $25 322
Not specified 339

What people switch to and from

Patients started taking Modafinil after stopping:

Treatment Patients
Methylphenidate (Ritalin) 25
Amphetamine-Dextroamphetamine (Adderall) 16
Armodafinil (Nuvigil) 14
Amantadine (Symmetrel) 9
Bupropion (Wellbutrin XL) 2

Show all 18 treatments patients report switching from

Patients stopped taking Modafinil and switched to:

Treatment Patients
Armodafinil (Nuvigil) 27
Amphetamine-Dextroamphetamine (Adderall) 26
Methylphenidate (Ritalin) 10
Dextroamphetamine (Dexedrine) 4
Amantadine (Symmetrel) 2

Show all 8 treatments patients report switching to

Last updated:

131 patient evaluations for Modafinil

Jun 26, 2015 (Started Jan 10, 2009)

  • Effectiveness
    Slight (for multiple sclerosis)
  • Effectiveness
    Moderate (for fatigue)
  • Effectiveness
    Major (for brain fog)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Stick to it. Take before noon. It could otherwise keep you awake at night.
Cost: < $25 monthly

Mar 19, 2009 (Started Jan 10, 2009)

  • Effectiveness
    Can’t tell (for brain fog)
  • Effectiveness
    None (for fatigue)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Feb 28, 2015 (Started Apr 15, 2012)

  • Effectiveness
    Moderate (for narcolepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 300 mg Daily

Oct 7, 2012 (Started Apr 15, 2012)

  • Effectiveness
    Major (for narcolepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily

  • 0 helpful marks

Sep 10, 2014 (Started Feb 28, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Great for people like me..Help you use your brain for positive effects.
Cost: $100-199 monthly

Feb 10, 2014 (Started Feb 28, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 131 patient evaluations for Modafinil