What is Carbidopa-Levodopa 25-100?

Category: Prescription Drugs

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Generic name: Carbidopa-Levodopa

Levodopa 100 mg, a dopamine precursor used to treat the movement disorder symptoms of Parkinson's disease is combined with carbidopa 25 mg. Carbidopa is often included with levodopa-containing drugs in order to boost its efficacy by slowing down the metabolism of dopamine.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 292 323
Stiffness/Spasticity 11 10
Tremor in hands 11 16
Multiple system atrophy 9 9
Restless legs syndrome 7 12
Dystonia 6 13

Show all 36 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 9
Moderate 60
Mild 123
None 143

Commonly reported side effects and conditions associated with Carbidopa-Levodopa 25-100

Side effect Patients
Jerky movements (dyskinesia) 27
Drowsiness 13
Nausea 13
Dizziness 5
Lightheadedness 5
Dry mouth 4

Show all 90 reported side effects

Dosages

Based on patients currently taking Carbidopa-Levodopa 25-100

Dosage Patients
25-100 mg three times daily 9
3 x 25 mg-100 mg daily 6
25-100 mg five times daily 5
6 x 25 mg-100 mg daily 4
25-100 mg four times daily 3
4 x 25 mg-100 mg daily 3
8 x 25 mg-100 mg daily 3
25 mg-100 mg daily 2
25 mg-100 mg twice daily 2
2 x 25-100 mg four times daily 2

See all 36 dosages

Why patients stopped taking Carbidopa-Levodopa 25-100

Multiple reasons could be selected

Reason Patients
Doctor's advice 14
Other 12
Did not seem to work 7
Personal research 7
Side effects too severe 7
Course of treatment ended 3
Change in health plan coverage 1
See all 42 patients who've stopped taking Carbidopa-Levodopa 25-100

Duration

Currently taking Carbidopa-Levodopa 25-100

Duration Patients
Less than 1 month 2
1 - 6 months 1
6 months - 1 year 3
1 - 2 years 7
2 - 5 years 21
5 - 10 years 28
10 years or more 9

Stopped taking Carbidopa-Levodopa 25-100

Duration Patients
Less than 1 month 4
1 - 6 months 8
6 months - 1 year 6
1 - 2 years 5
2 - 5 years 12
5 - 10 years 6
10 years or more 1
Adherence
Adherence Evaluations
Always 250
Usually 64
Sometimes 12
Never taken as prescribed 9
Burden
Burden Evaluations
Very hard to take 10
Somewhat hard to take 58
A little hard to take 80
Not at all hard to take 187
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 1
$50-99 5
$25-49 37
< $25 229
Not specified 63

What people switch to and from

Patients started taking Carbidopa-Levodopa 25-100 after stopping:

Treatment Patients
Carbidopa-Levodopa CR (Sinemet CR) 4
Ropinirole (Requip) 3
Carbidopa-Entacapone-Levodopa (Stalevo) 2
Carbidopa-Levodopa (Sinemet) 2
Carbidopa Levodopa ER (Rytary XR) 2

Show all 8 treatments patients report switching from

Patients stopped taking Carbidopa-Levodopa 25-100 and switched to:

Treatment Patients
Carbidopa Levodopa ER (Rytary XR) 9
Carbidopa-Entacapone-Levodopa (Stalevo) 3
Carbidopa-Levodopa (Sinemet) 1
Pramipexole (Mirapex) 1
Last updated:

30 patient evaluations for Carbidopa-Levodopa 25-100

Aug 10, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for dystonia)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (Nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Daily
Advice & Tips: I eat crackers before taking the medication so I don't vomit. I take 2 tablets times 4 times daily of the 25/100 mg. tablets
Cost: < $25 monthly

May 25, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Moderate (for dystonia)
  • Side effects
    Moderate (Nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Daily
Advice & Tips: I eat crackers before taking the medication so I don't vomit. I take 2 tablets times 4 times daily of the 25/100 mg. tablets
Cost: < $25 monthly

Jan 17, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for dystonia)
  • Side effects
    Mild (Nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Daily
Advice & Tips: I eat crackers before taking the medication so I don't vomit.
Cost: < $25 monthly

Oct 10, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Slight (for dystonia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg-100 mg Daily
Cost: < $25 monthly

Sep 14, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Slight (for dystonia)
  • Side effects
    Mild (Nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Daily
Advice & Tips: crackers help
Cost: < $25 monthly

Jul 13, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Slight (for dystonia)
  • Side effects
    Moderate (Nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Daily
Advice & Tips: I continue to be nausea, but crackers help.
Cost: < $25 monthly

  • 0 helpful marks

Apr 20, 2017 (Started Sep 28, 2012)

  • Effectiveness
    None (for Parkinson's disease)
  • Side effects
    Moderate (face grimace)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg-100 mg Four times daily
Cost: < $25 monthly
Side effects: face grimace

Feb 6, 2010 (Started Sep 28, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Moderate (face grimace)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Cost: < $25 monthly
Side effects: face grimace

  • 0 helpful marks

Feb 3, 2017 (Started Jun 21, 2010)

  • Effectiveness
    Moderate (for Tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (Jerky movements (dyskinesia), Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Nov 28, 2016 (Started Jun 21, 2010)

  • Effectiveness
    Moderate (for Tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (Jerky movements (dyskinesia), Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Dec 15, 2015 (Started Jun 21, 2010)

  • Effectiveness
    Moderate (for Tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (Jerky movements (dyskinesia), Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Advice & Tips: This summer I had to lower my total intake of carbidopa / levodopa as I began to experience dyskinesia in the evenings.  If I keep my daily levodopa dose at or below 1200 mgs, I seldom experience any dyskinesia.
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Dec 17, 2012 (Started Jun 21, 2010)

  • Effectiveness
    Moderate (for Tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Advice & Tips: I take the regular Sinemet pill as a 'back-up' to my extended release Sinemet when I go to the gym, paint or do something during which time I hope to lesson my tremors - it does seem to help.
Cost: < $25 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Jul 6, 2010 (Started Jun 21, 2010)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Usually
  • Burden
    A little hard to take
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Jun 30, 2010 (Started Jun 21, 2010)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Jun 29, 2010 (Started Jun 21, 2010)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

  • 0 helpful marks
Last updated:
Showing 3 of 30 patient evaluations for Carbidopa-Levodopa 25-100