What is Carbidopa-Levodopa 25-100?

Category: Prescription Drugs

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Generic name: Carbidopa-Levodopa

Levodopa 100 mg, a dopamine precursor used to treat the movement disorder symptoms of Parkinson's disease is combined with carbidopa 25 mg. Carbidopa is often included with levodopa-containing drugs in order to boost its efficacy by slowing down the metabolism of dopamine.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's Disease 271 287
Stiffness/Spasticity 11 10
Tremor in hands 11 14
MSA (Multiple System Atrophy) 9 9
Dystonia 6 10
Increase effect of another treatment 6 9

Show all 34 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 8
Moderate 54
Mild 106
None 127

Commonly reported side effects and conditions associated with Carbidopa-Levodopa 25-100

Side effect Patients
Dyskinesia 19
Drowsiness 13
Nausea 12
Jerky movements (dyskinesia) 10
Dizziness 5
Dry mouth 4

Show all 81 reported side effects

Dosages

Based on patients currently taking Carbidopa-Levodopa 25-100

Dosage Patients
3 x 25 mg-100 mg daily 8
4 x 25 mg-100 mg daily 6
25 mg-100 mg daily 3
25 mg-100 mg three times daily 3
25 mg-100 mg four times daily 3
6 x 25 mg-100 mg daily 3
8 x 25 mg-100 mg daily 3
25-100 mg three times daily 2
2 x 25-100 mg four times daily 2
25 mg-100 mg five times daily 2

See all 29 dosages

Why patients stopped taking Carbidopa-Levodopa 25-100

Multiple reasons could be selected

Reason Patients
Doctor's advice 14
Other 11
Personal research 6
Side effects too severe 6
Did not seem to work 5
Course of treatment ended 3
Change in health plan coverage 1
See all 37 patients who’ve stopped taking Carbidopa-Levodopa 25-100

Duration

Currently taking Carbidopa-Levodopa 25-100

Duration Patients
1 - 6 months 2
6 months - 1 year 2
1 - 2 years 2
2 - 5 years 20
5 - 10 years 23
10 years or more 9

Stopped taking Carbidopa-Levodopa 25-100

Duration Patients
Less than 1 month 4
1 - 6 months 6
6 months - 1 year 5
1 - 2 years 4
2 - 5 years 11
5 - 10 years 6
10 years or more 1
Adherence
Adherence Evaluations
Always 216
Usually 60
Sometimes 12
Never taken as prescribed 7
Burden
Burden Evaluations
Very hard to take 9
Somewhat hard to take 52
A little hard to take 72
Not at all hard to take 162
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 1
$50-99 4
$25-49 32
< $25 200
Not specified 58

What people switch to and from

Patients started taking Carbidopa-Levodopa 25-100 after stopping:

Treatment Patients
Carbidopa-Levodopa CR (Sinemet CR) 4
Carbidopa-Levodopa (Sinemet) 2
Carbidopa Levodopa ER (Rytary XR) 2
Entacapone (Comtan) 2
Carbidopa-Entacapone-Levodopa (Stalevo) 1

Show all 7 treatments patients report switching from

Patients stopped taking Carbidopa-Levodopa 25-100 and switched to:

Treatment Patients
Carbidopa Levodopa ER (Rytary XR) 7
Carbidopa-Entacapone-Levodopa (Stalevo) 2
Carbidopa-Levodopa (Sinemet) 1
Last updated:

28 patient evaluations for Carbidopa-Levodopa 25-100

137 members have decided to share their profiles only with other members of PatientsLikeMe.

J.Marley
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J.Marley
Sex: M
Data Quality: 3 stars
On
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: mild
I am: n
I have:
Parkinson's

See J.Marley's full Carbidopa-Levodopa 25-100 history

Nov 28, 2016 (Started Jun 21, 2010)

  • Effectiveness
    Moderate (for Tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    Mild (Nausea and vomiting, Dyskinesia, Occasional nausea and vomiting)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Dec 15, 2015 (Started Jun 21, 2010)

  • Effectiveness
    Moderate (for Tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    Mild (Nausea and vomiting, Dyskinesia, Occasional nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Advice & Tips: This summer I had to lower my total intake of carbidopa / levodopa as I began to experience dyskinesia in the evenings.  If I keep my daily levodopa dose at or below 1200 mgs, I seldom experience any dyskinesia.
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Dec 17, 2012 (Started Jun 21, 2010)

  • Effectiveness
    Moderate (for Tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Advice & Tips: I take the regular Sinemet pill as a 'back-up' to my extended release Sinemet when I go to the gym, paint or do something during which time I hope to lesson my tremors - it does seem to help.
Cost: < $25 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Jul 6, 2010 (Started Jun 21, 2010)

  • Effectiveness
    Slight (for Parkinson's Disease)
  • Side effects
    Mild (Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Usually
  • Burden
    A little hard to take
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Jun 30, 2010 (Started Jun 21, 2010)

  • Effectiveness
    Slight (for Parkinson's Disease)
  • Side effects
    Mild (Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

Jun 29, 2010 (Started Jun 21, 2010)

  • Effectiveness
    Slight (for Parkinson's Disease)
  • Side effects
    Mild (Nausea and vomiting, Occasional nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: $25-49 monthly
Side effects: Nausea and vomiting, Occasional nausea and vomiting

  • 0 helpful marks
Napiejoe
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Napiejoe
Sex: M
Data Quality: 3 stars
On
Mouth/throat: mild
Arms: mild
Chest: none
Legs: mild
I am: g
I have:
Parkinson's

See Napiejoe's full Carbidopa-Levodopa 25-100 history

Nov 10, 2016 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Dyskinesia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25-250 mg Five times daily
Cost: $25-49 monthly

May 26, 2015 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Moderate (Dyskinesia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4 x 25 mg-250 mg Daily
Cost: < $25 monthly

May 19, 2013 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    Mild (Dyskinesia)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 4 x 25 mg-100 mg Daily
Advice & Tips: I use a talking alarm watch to help me take my medication on time.
Cost: < $25 monthly

May 24, 2009 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 25 mg-100 mg Daily
Advice & Tips: Take your pills on time
Cost: $25-49 monthly

  • 0 helpful marks
margie99
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margie99
Sex: F
Data Quality: 3 stars
On
Mouth/throat: mild
Arms: mild
Chest: mild
Legs: moderate
I am: g
I have:
Parkinson's

See margie99's full Carbidopa-Levodopa 25-100 history

Oct 10, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Major (for Parkinson's Disease)
  • Effectiveness
    Slight (for Dystonia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg-100 mg Daily
Cost: < $25 monthly

Sep 14, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Effectiveness
    Slight (for Dystonia)
  • Side effects
    Mild (Nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Daily
Advice & Tips: crackers help
Cost: < $25 monthly

Jul 13, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Parkinson's Disease)
  • Effectiveness
    Slight (for Dystonia)
  • Side effects
    Moderate (Nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Daily
Advice & Tips: I continue to be nausea, but crackers help.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 28 patient evaluations for Carbidopa-Levodopa 25-100