Restless legs syndrome

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What is restless legs syndrome?

Restless legs syndrome (RLS) is a neurological disorder characterized by an unpleasant sensation in the legs and an urge to move them for relief; usually occurs during periods of inactivity, particularly at night. RLS sensations may also be felt in the arms or other parts of the body.

Common symptoms reported by people with restless legs syndrome

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
Last updated:

Treatments taken by people with restless legs syndrome

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Mirapex)
Type
Prescription Drug
How many have tried
68
Treatment name(s)

(Requip)
Type
Prescription Drug
How many have tried
68
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
49
Tried for
pain (25) restless legs syndrome (25)
2 more
Treatment name(s)

(Klonopin)
Type
Prescription Drug
How many have tried
30
Tried for
anxious mood (22) restless legs syndrome (9)
1 more
Treatment name(s)

(Norco)
Type
Prescription Drug
How many have tried
25
Tried for
pain (25)
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
24
Tried for
pain (21) restless legs syndrome (3)
Treatment name(s)

(Lexapro)
Type
Prescription Drug
How many have tried
20
Tried for
depressed mood (17) anxious mood (10)
2 more
Treatment name(s)

(Lyrica)
Type
Prescription Drug
How many have tried
17
Tried for
pain (15) restless legs syndrome (4)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
15
Tried for
depressed mood (12) anxious mood (4)
3 more
Treatment name(s)

(Cannabidiol CBD oil)
Type
Other
How many have tried
14
Tried for
pain (13) anxious mood (8)
3 more

Data from patients with restless legs syndrome, who reported starting treatments within the last 5 years.
Last updated:

Compare treatments taken by people with restless legs syndrome

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Mirapex)
Perceived effectiveness
for restless legs syndrome (39 evaluations)
Side effects
nausea difficulty staying asleep 24 more
Total evaluations
41
Treatment name(s)

(Requip)
Perceived effectiveness
for restless legs syndrome (39 evaluations)
Side effects
nausea dizziness and feeling faint 12 more
Total evaluations
50
Treatment name(s)

(Neurontin)
Perceived effectiveness
for pain (40 evaluations)
Side effects
excessive daytime sleepiness (somnolence) memory problems 21 more
Total evaluations
53
Tried for
pain (25) restless legs syndrome (25)
2 more
Treatment name(s)

(Klonopin)
Perceived effectiveness
for anxious mood (12 evaluations)
Side effects
headaches increased sleepiness 3 more
Total evaluations
18
Tried for
anxious mood (22) restless legs syndrome (9)
1 more
Treatment name(s)

(Norco)
Perceived effectiveness
for pain (15 evaluations)
Side effects
drowsiness chronic constipation 4 more
Total evaluations
16
Tried for
pain (25)
Treatment name(s)

(Ultram)
Perceived effectiveness
for pain (8 evaluations)
Side effects
nausea chronic constipation 5 more
Total evaluations
8
Tried for
pain (21) restless legs syndrome (3)
Treatment name(s)

(Lexapro)
Perceived effectiveness
for depressed mood (11 evaluations)
Side effects
drowsiness agitation 16 more
Total evaluations
12
Tried for
depressed mood (17) anxious mood (10)
2 more
Treatment name(s)

(Lyrica)
Perceived effectiveness
for pain (15 evaluations)
Side effects
blurry vision fatigue 7 more
Total evaluations
15
Tried for
pain (15) restless legs syndrome (4)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for depressed mood (15 evaluations)
Side effects
abdominal pain bipolar depressive episodes 32 more
Total evaluations
21
Tried for
depressed mood (12) anxious mood (4)
3 more
Treatment name(s)

(Cannabidiol CBD oil)
Perceived effectiveness
for pain (9 evaluations)
Side effects
agitation paranoia
Total evaluations
9
Tried for
pain (13) anxious mood (8)
3 more
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with restless legs syndrome, who reported starting treatments within the last 5 years.
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Who has restless legs syndrome on PatientsLikeMe?


Age
Age Proportion # of patients
<20 8
20s 88
30s 333
40s 783
50s 1036
60s 825
70+ 311
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 327
20-29 years 282
30-39 years 418
40-49 years 402
50-59 years 195
60-69 years 44
70+ years 10

Distribution of sex

Sex
Sex Proportion # of patients
Male 542
Female 2849

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 1822
Not Diagnosed 269

These charts show data from restless legs syndrome (RLS) patients who have completed their condition history
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