What is Sodium Oxybate?

Category: Prescription Drugs

Most popular types: Xyrem

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Sodium oxybate is the salt form of the drug gamma-Hydroxybutyric acid (4-hydroxybutanoic acid, C4H8O3), commonly abbreviated GHB. Historically, GHB has been used in a medical setting as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Cataplexy 18 5
Sleeplessness 18 12
Fibromyalgia 12 4
Excessive daytime sleepiness (somnolence) 8 11
Idiopathic hypersomnia 7 5

Show all 21 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 3
Moderate 9
Mild 22
None 9

Commonly reported side effects and conditions associated with Sodium Oxybate

Side effect Patients
Nausea 8
Night sweats 3
Brain fog 2
Dizziness 2
Headaches 2
Sleep eating 2

Show all 27 reported side effects

Dosages

Based on patients currently taking Sodium Oxybate

Dosage Patients
4.5 g twice daily 2
3.5 g twice daily 1
4.5 mg twice daily 1
1,000 mg monthly 1
500 mg twice daily 1

Why patients stopped taking Sodium Oxybate

Multiple reasons could be selected

Reason Patients
Side effects too severe 8
Did not seem to work 6
Change in health plan coverage 1
Course of treatment ended 1
Expense 1
Other 1
See all 14 patients who've stopped taking Sodium Oxybate

Duration

Currently taking Sodium Oxybate

Duration Patients
1 - 2 years 1
2 - 5 years 4
5 - 10 years 1

Stopped taking Sodium Oxybate

Duration Patients
Less than 1 month 1
1 - 6 months 7
6 months - 1 year 2
1 - 2 years 1
2 - 5 years 3
Adherence
Adherence Evaluations
Always 29
Usually 11
Sometimes 3
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 12
A little hard to take 18
Not at all hard to take 10
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 0
$50-99 0
$25-49 11
< $25 19
Not specified 9

What people switch to and from

Patients started taking Sodium Oxybate after stopping:

Treatment Patients
Armodafinil (Nuvigil) 1
Clonazepam (Klonopin) 1
Gabapentin (Neurontin) 1
Progesterone (Prometrium) 1
Topiramate (Topamax) 1

Show all 6 treatments patients report switching from

Patients stopped taking Sodium Oxybate and switched to:

Treatment Patients
Baclofen (Mylan-Baclofen) 1
Last updated:
There are no evaluations for Sodium Oxybate.