What is Desipramine?

Category: Prescription Drugs

Most popular types: Norpramin Pertofrane

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Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin® and Pertofrane®. It is used to treat depression, neuropathic pain, and ADHD.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Nerve pain (neuralgia) 16 11
Depressed mood 10 6
Major depressive disorder 9 8
Pain 5 1
Complex regional pain syndrome type I 3 0

Show all 24 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
4
Moderate
7
Mild
7
None
19

Commonly reported side effects and conditions associated with Desipramine

Side effect Patients
Dry mouth at night 2
Confusion 1
Delayed sleep phase syndrome 1
Dizziness upon standing 1
Dry mouth 1
Ejaculation delayed 1

Show all 24 reported side effects

Dosages

Based on patients currently taking Desipramine

Dosage Patients
25 mg daily 1
75 mg daily 1
110 mg daily 1
200 mg daily 1

Why patients stopped taking Desipramine

Multiple reasons could be selected

Reason Patients
Did not seem to work 14
Doctor's advice 12
Side effects too severe 10
Course of treatment ended 5
Other 3
Personal research 1
See all 32 patients who've stopped taking Desipramine

Duration

Currently taking Desipramine

Duration Patients
1 - 6 months 1
6 months - 1 year 1
5 - 10 years 1
10 years or more 1

Stopped taking Desipramine

Duration Patients
Less than 1 month 3
1 - 6 months 11
6 months - 1 year 4
1 - 2 years 8
2 - 5 years 3
5 - 10 years 2
10 years or more 1
Adherence
Adherence Evaluations
Always 29
Usually 7
Sometimes 1
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 2
A little hard to take 5
Not at all hard to take 30
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 1
$50-99 4
$25-49 0
< $25 16
Not specified 16

What people switch to and from

Patients started taking Desipramine after stopping:

Treatment Patients
Bupropion (Wellbutrin XL) 2
Fluoxetine (Prozac) 1
Imipramine (Tofranil) 1
Mirtazapine (Remeron) 1
Risperidone (Risperdal) 1

Show all 7 treatments patients report switching from

Patients stopped taking Desipramine and switched to:

Treatment Patients
Fluoxetine (Prozac) 3
Imipramine (Tofranil) 1
Paroxetine (Paxil) 1
Last updated:

3 patient evaluations for Desipramine

Jul 7, 2010 (Started Jan 01, 1992)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Advice & Tips: I have a "pill minder" box" that I picked up at Walgreens for my day meds and another for night meds. So their very few problems in remembering to take my medications.

  • 0 helpful marks

Jul 1, 2010 (Started May 07, 2010)

  • Effectiveness
    Can't tell (for pain)
  • Effectiveness
    Can't tell (for sleep problems)
  • Side effects
    Severe (racing heart feeling)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Jul 1, 2008 (Started Apr 01, 2008)

  • Effectiveness
    None (for Treat my mood condition(s))
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Desipramine