Major depressive disorder

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What is major depressive disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

Common symptoms reported by people with major depressive disorder

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people for major depressive disorder

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Wellbutrin)
Type
Prescription Drug
How many have tried
16133
Tried for
major depressive disorder (175)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
11844
Tried for
major depressive disorder (119)
Treatment name(s)

(Effexor XR)
Type
Prescription Drug
How many have tried
15519
Tried for
major depressive disorder (113)
Treatment name(s)

(Zoloft)
Type
Prescription Drug
How many have tried
19157
Tried for
major depressive disorder (105)
Treatment name(s)

(Talk therapy)
Type
Psychotherapy
How many have tried
23625
Tried for
major depressive disorder (98)
Treatment name(s)

(Lexapro)
Type
Prescription Drug
How many have tried
10571
Tried for
major depressive disorder (85)
Treatment name(s)

(Prozac)
Type
Prescription Drug
How many have tried
18406
Tried for
major depressive disorder (63)
Treatment name(s)

(Celexa)
Type
Prescription Drug
How many have tried
10841
Tried for
major depressive disorder (36)

Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
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Compare treatments taken by people with major depressive disorder

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Wellbutrin)
Perceived effectiveness
for major depressive disorder (80 evaluations)
Side effects
dry mouth anxious mood 49 more
Total evaluations
82
Tried for
major depressive disorder (175)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for major depressive disorder (58 evaluations)
Side effects
dry mouth decreased sex drive (libido) 23 more
Total evaluations
59
Tried for
major depressive disorder (119)
Treatment name(s)

(Effexor XR)
Perceived effectiveness
for major depressive disorder (69 evaluations)
Side effects
nausea dizziness 50 more
Total evaluations
72
Tried for
major depressive disorder (113)
Treatment name(s)

(Zoloft)
Perceived effectiveness
for major depressive disorder (55 evaluations)
Side effects
nausea weight gain 53 more
Total evaluations
57
Tried for
major depressive disorder (105)
Treatment name(s)

(Talk therapy)
Perceived effectiveness
for major depressive disorder (33 evaluations)
Side effects
flashbacks emotional lability 9 more
Total evaluations
37
Tried for
major depressive disorder (98)
Treatment name(s)

(Lexapro)
Perceived effectiveness
for major depressive disorder (46 evaluations)
Side effects
decreased sex drive (libido) dry mouth 40 more
Total evaluations
46
Tried for
major depressive disorder (85)
Treatment name(s)

(Prozac)
Perceived effectiveness
for major depressive disorder (37 evaluations)
Side effects
headaches nausea 25 more
Total evaluations
39
Tried for
major depressive disorder (63)
Treatment name(s)

(Celexa)
Perceived effectiveness
for major depressive disorder (28 evaluations)
Side effects
dizziness nausea 8 more
Total evaluations
28
Tried for
major depressive disorder (36)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
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Who has major depressive disorder on PatientsLikeMe?

  • 28 new patients joined this month
  • 33050 say MDD is their primary condition

Age
Age Proportion # of patients
<20 158
20s 3384
30s 8643
40s 13472
50s 17258
60s 12927
70+ 3842
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 8857
20-29 years 3723
30-39 years 2740
40-49 years 1755
50-59 years 611
60-69 years 115
70+ years 21

Distribution of sex

Sex
Sex Proportion # of patients
Male 12428
Female 47586

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 23958
Not Diagnosed 2340

These charts show data from MDD patients who have completed their condition history
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