Major depressive disorder

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What is major depressive disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

Common symptoms reported by people with major depressive disorder

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people for major depressive disorder

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Wellbutrin)
Type
Prescription Drug
How many have tried
15970
Tried for
major depressive disorder (339)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
11758
Tried for
major depressive disorder (229)
Treatment name(s)

(Talk therapy)
Type
Psychotherapy
How many have tried
23424
Tried for
major depressive disorder (221)
Treatment name(s)

(Effexor XR)
Type
Prescription Drug
How many have tried
15436
Tried for
major depressive disorder (194)
Treatment name(s)

(Zoloft)
Type
Prescription Drug
How many have tried
19011
Tried for
major depressive disorder (187)
Treatment name(s)

(Lexapro)
Type
Prescription Drug
How many have tried
10466
Tried for
major depressive disorder (164)
Treatment name(s)

(Prozac)
Type
Prescription Drug
How many have tried
18279
Tried for
major depressive disorder (146)
Treatment name(s)

(Celexa)
Type
Prescription Drug
How many have tried
10773
Tried for
major depressive disorder (89)

Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
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Compare treatments taken by people with major depressive disorder

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Wellbutrin)
Perceived effectiveness
for major depressive disorder (175 evaluations)
Side effects
dry mouth suicidal thoughts or urges 96 more
Total evaluations
184
Tried for
major depressive disorder (339)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for major depressive disorder (125 evaluations)
Side effects
dry mouth weight gain 85 more
Total evaluations
136
Tried for
major depressive disorder (229)
Treatment name(s)

(Talk therapy)
Perceived effectiveness
for major depressive disorder (94 evaluations)
Side effects
flashbacks depressed mood 27 more
Total evaluations
114
Tried for
major depressive disorder (221)
Treatment name(s)

(Effexor XR)
Perceived effectiveness
for major depressive disorder (127 evaluations)
Side effects
nausea dry mouth 82 more
Total evaluations
134
Tried for
major depressive disorder (194)
Treatment name(s)

(Zoloft)
Perceived effectiveness
for major depressive disorder (122 evaluations)
Side effects
weight gain nausea 85 more
Total evaluations
128
Tried for
major depressive disorder (187)
Treatment name(s)

(Lexapro)
Perceived effectiveness
for major depressive disorder (95 evaluations)
Side effects
dry mouth decreased sex drive (libido) 56 more
Total evaluations
97
Tried for
major depressive disorder (164)
Treatment name(s)

(Prozac)
Perceived effectiveness
for major depressive disorder (92 evaluations)
Side effects
nausea dizziness 48 more
Total evaluations
97
Tried for
major depressive disorder (146)
Treatment name(s)

(Celexa)
Perceived effectiveness
for major depressive disorder (49 evaluations)
Side effects
dizziness nausea 20 more
Total evaluations
50
Tried for
major depressive disorder (89)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
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Who has major depressive disorder on PatientsLikeMe?

  • 116 new patients joined this month
  • 32439 say MDD is their primary condition

Age
Age Proportion # of patients
<20 178
20s 3735
30s 8964
40s 13775
50s 17093
60s 11999
70+ 3235
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 8849
20-29 years 3735
30-39 years 2742
40-49 years 1756
50-59 years 613
60-69 years 114
70+ years 19

Distribution of sex

Sex
Sex Proportion # of patients
Male 12256
Female 47044

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 23968
Not Diagnosed 2342

These charts show data from MDD patients who have completed their condition history
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