What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,348 3,198
Depressed mood 2,074 1,221
Major depressive disorder 1,905 1,155
Generalized anxiety disorder 796 567
Myalgic encephalomyelitis/chronic fatigue syndrome 694 384
Pain 532 313

Show all 328 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 927
Moderate 1,013
Mild 1,140
None 1,760

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 333
Nausea 286
Dry mouth 167
Dizziness 159
Decreased sex drive (libido) 155
Sweating increased 100

Show all 740 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 416
30 mg daily 168
120 mg daily 131
60 mg twice daily 74
90 mg daily 73
20 mg daily 61
30 mg twice daily 26
40 mg daily 20
20 mg twice daily 15
120 mg twice daily 13

See all 42 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1749
Did not seem to work 1549
Doctor's advice 583
Expense 442
Other 434
Personal research 173
Change in health plan coverage 159
Course of treatment ended 70
See all 3484 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 4
1 - 6 months 36
6 months - 1 year 93
1 - 2 years 145
2 - 5 years 307
5 - 10 years 327
10 years or more 161

Stopped taking Duloxetine

Duration Patients
Less than 1 month 814
1 - 6 months 934
6 months - 1 year 549
1 - 2 years 497
2 - 5 years 515
5 - 10 years 155
10 years or more 35
Adherence
Adherence Evaluations
Always 4051
Usually 429
Sometimes 75
Never taken as prescribed 285
Burden
Burden Evaluations
Very hard to take 300
Somewhat hard to take 368
A little hard to take 573
Not at all hard to take 3599
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 191
$50-99 433
$25-49 691
< $25 1556
Not specified 1843

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 152
Fluoxetine (Prozac) 130
Venlafaxine (Effexor XR) 120
Sertraline (Zoloft) 111
Citalopram (Celexa) 97

Show all 74 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 77
Venlafaxine (Effexor XR) 69
Gabapentin (Neurontin) 58
Bupropion (Wellbutrin XL) 36
Escitalopram (Lexapro) 36

Show all 77 treatments patients report switching to

Last updated:

320 patient evaluations for Duloxetine

Jun 17, 2017 (Started Feb 23, 2017)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    Moderate (dizziness, tremor(s))
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Mar 1, 2017 (Started Oct 30, 2013)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (insomnia, headaches, bitter taste, daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

Jul 10, 2016 (Started Oct 30, 2013)

  • Effectiveness
    Can't tell (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Moderate (insomnia, headaches, bitter taste, daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

Jul 7, 2016 (Started Oct 30, 2013)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Mild (insomnia, headaches, bitter taste, daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

Jul 3, 2016 (Started Oct 30, 2013)

  • Effectiveness
    Can't tell (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Mild (daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

Nov 2, 2013 (Started Oct 30, 2013)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: $50-99 monthly

Oct 30, 2013 (Started Oct 30, 2013)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Mild (daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks

Nov 20, 2016 (Started May 15, 2012)

  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (muscle and joint pain, muscle fatigue)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 180 mg Twice daily
Advice & Tips: This medication is habit forming and it’s withdrawal effects took nearly SEVEN MONTHS to wear off! Be careful when you are prescribed this medication..
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 320 patient evaluations for Duloxetine