What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,153 3,109
Depressed mood 2,011 1,173
Major depressive disorder 1,793 1,097
Generalized anxiety disorder 769 541
Myalgic encephalomyelitis/chronic fatigue syndrome 693 381
Pain 524 302

Show all 312 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 904
Moderate 981
Mild 1,115
None 1,673

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 302
Nausea 278
Dry mouth 161
Dizziness 155
Decreased sex drive (libido) 151
Sweating increased 100

Show all 728 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 433
30 mg daily 170
120 mg daily 120
90 mg daily 85
60 mg twice daily 79
20 mg daily 68
30 mg twice daily 45
40 mg daily 31
120 mg twice daily 20
20 mg twice daily 15

See all 49 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1709
Did not seem to work 1498
Doctor's advice 566
Expense 443
Other 417
Personal research 168
Change in health plan coverage 158
Course of treatment ended 66
See all 3379 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 4
1 - 6 months 81
6 months - 1 year 104
1 - 2 years 187
2 - 5 years 361
5 - 10 years 311
10 years or more 130

Stopped taking Duloxetine

Duration Patients
Less than 1 month 732
1 - 6 months 955
6 months - 1 year 553
1 - 2 years 482
2 - 5 years 499
5 - 10 years 142
10 years or more 33
Adherence
Adherence Evaluations
Always 3921
Usually 410
Sometimes 69
Never taken as prescribed 273
Burden
Burden Evaluations
Very hard to take 294
Somewhat hard to take 360
A little hard to take 543
Not at all hard to take 3476
Cost per month
Cost per month Evaluations
$200+ 124
$100-199 188
$50-99 428
$25-49 674
< $25 1502
Not specified 1757

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 147
Fluoxetine (Prozac) 116
Venlafaxine (Effexor XR) 110
Sertraline (Zoloft) 93
Citalopram (Celexa) 89

Show all 70 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 75
Venlafaxine (Effexor XR) 60
Gabapentin (Neurontin) 54
Sertraline (Zoloft) 35
Bupropion (Wellbutrin XL) 33

Show all 72 treatments patients report switching to

Last updated:

318 patient evaluations for Duloxetine

May 9, 2016 (Started Jan 01, 2006)

  • Effectiveness
    None (for generalized anxiety disorder)
  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Cost: < $25 monthly

Jul 13, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

Jun 18, 2011 (Started Jan 01, 2006)

  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: Have a high drug tolerancy.
Cost: < $25 monthly

  • 0 helpful marks

Apr 28, 2016 (Started Jan 05, 2009)

  • Effectiveness
    Can’t tell (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily

  • 0 helpful marks

Apr 24, 2016 (Started Sep 01, 2010)

  • Effectiveness
    Slight (for Pain)
  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Slight (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

Jan 5, 2015 (Started Sep 01, 2010)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Moderate (for Pain)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    None (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

Nov 10, 2014 (Started Sep 01, 2010)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for Pain)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 318 patient evaluations for Duloxetine