What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
fibromyalgia 6,073 3,054
Depressed mood 1,996 1,147
major depressive disorder 1,753 1,071
generalized anxiety disorder 756 533
myalgic encephalomyelitis/chronic fatigue syndrome 693 378
Pain 521 299

Show all 353 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 895
Moderate 972
Mild 1,105
None 1,636

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 297
Nausea 285
Dizziness 159
Dry mouth 159
Sex drive (libido) decreased 157
Sweating increased 100

Show all 725 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 535
30 mg daily 224
120 mg daily 127
90 mg daily 100
60 mg twice daily 99
20 mg daily 89
30 mg twice daily 56
40 mg daily 36
120 mg twice daily 27
20 mg twice daily 15

See all 59 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1692
Did not seem to work 1479
Doctor's advice 558
Expense 435
Other 415
Personal research 166
Change in health plan coverage 154
Course of treatment ended 67
See all 3341 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 21
1 - 6 months 87
6 months - 1 year 120
1 - 2 years 231
2 - 5 years 440
5 - 10 years 384
10 years or more 178

Stopped taking Duloxetine

Duration Patients
Less than 1 month 724
1 - 6 months 950
6 months - 1 year 547
1 - 2 years 475
2 - 5 years 492
5 - 10 years 137
10 years or more 32
Adherence
Adherence Evaluations
Always 3859
Usually 408
Sometimes 68
Never taken as prescribed 273
Burden
Burden Evaluations
Very hard to take 292
Somewhat hard to take 357
A little hard to take 540
Not at all hard to take 3419
Cost per month
Cost per month Evaluations
$200+ 124
$100-199 187
$50-99 425
$25-49 670
< $25 1474
Not specified 1728

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 141
Fluoxetine (Prozac) 109
Venlafaxine (Effexor XR) 103
Sertraline (Zoloft) 89
Citalopram (Celexa) 81

Show all 71 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 72
Venlafaxine (Effexor XR) 57
Gabapentin (Neurontin) 50
Sertraline (Zoloft) 33
Bupropion (Wellbutrin XL) 32

Show all 70 treatments patients report switching to

Last updated:

317 patient evaluations for Duloxetine

May 9, 2016 (Started Jan 01, 2006)

  • Effectiveness
    None (for generalized anxiety disorder)
  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Cost: < $25 monthly

Jul 13, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

Jun 18, 2011 (Started Jan 01, 2006)

  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: Have a high drug tolerancy.
Cost: < $25 monthly

  • 0 helpful marks

Apr 28, 2016 (Started Jan 05, 2009)

  • Effectiveness
    Can’t tell (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily

  • 0 helpful marks

Apr 24, 2016 (Started Sep 01, 2010)

  • Effectiveness
    Slight (for Pain)
  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Slight (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

Jan 5, 2015 (Started Sep 01, 2010)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Moderate (for Pain)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    None (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

Nov 10, 2014 (Started Sep 01, 2010)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for Pain)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 317 patient evaluations for Duloxetine