What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

false

Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,340 3,199
Depressed mood 2,077 1,228
Major depressive disorder 1,911 1,159
Generalized anxiety disorder 797 568
Myalgic encephalomyelitis/chronic fatigue syndrome 693 385
Pain 533 316

Show all 326 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 928
Moderate 1,014
Mild 1,144
None 1,765

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 334
Nausea 287
Decreased sex drive (libido) 184
Dry mouth 169
Dizziness 159
Sweating increased 100

Show all 733 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 414
30 mg daily 182
120 mg daily 140
90 mg daily 77
60 mg twice daily 70
20 mg daily 64
30 mg twice daily 26
40 mg daily 16
20 mg twice daily 13
120 mg twice daily 12

See all 43 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1747
Did not seem to work 1546
Doctor's advice 582
Expense 443
Other 434
Personal research 175
Change in health plan coverage 160
Course of treatment ended 69
See all 3479 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 1
1 - 6 months 33
6 months - 1 year 90
1 - 2 years 144
2 - 5 years 307
5 - 10 years 340
10 years or more 168

Stopped taking Duloxetine

Duration Patients
Less than 1 month 814
1 - 6 months 933
6 months - 1 year 548
1 - 2 years 495
2 - 5 years 515
5 - 10 years 155
10 years or more 35
Adherence
Adherence Evaluations
Always 4056
Usually 433
Sometimes 75
Never taken as prescribed 287
Burden
Burden Evaluations
Very hard to take 300
Somewhat hard to take 369
A little hard to take 574
Not at all hard to take 3608
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 191
$50-99 434
$25-49 691
< $25 1559
Not specified 1850

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 152
Fluoxetine (Prozac) 129
Venlafaxine (Effexor XR) 123
Sertraline (Zoloft) 111
Citalopram (Celexa) 98

Show all 74 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 77
Venlafaxine (Effexor XR) 69
Gabapentin (Neurontin) 59
Escitalopram (Lexapro) 37
Bupropion (Wellbutrin XL) 36

Show all 77 treatments patients report switching to

Last updated:

321 patient evaluations for Duloxetine

Oct 15, 2016 (Started Jul 01, 2010)

  • Effectiveness
    Can't tell (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Can't tell (for generalized anxiety disorder)
  • Effectiveness
    Can't tell (for fibromyalgia)
  • Effectiveness
    Can't tell (for bipolar II disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: $50-99 monthly

Feb 25, 2013 (Started Jul 01, 2010)

  • Effectiveness
    Can't tell (for generalized anxiety disorder)
  • Effectiveness
    Can't tell (for bipolar II disorder)
  • Effectiveness
    Can't tell (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks

Aug 31, 2016 (Started Jun 05, 2009)

  • Effectiveness
    Moderate (for peripheral neuritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: $50-99 monthly
Side effects: fuzzy thinking

Jul 29, 2011 (Started Jun 05, 2009)

  • Effectiveness
    Moderate (for peripheral neuritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: $50-99 monthly
Side effects: fuzzy thinking

Jan 26, 2010 (Started Jun 05, 2009)

  • Effectiveness
    Slight (for peripheral neuritis)
  • Side effects
    Mild (fuzzy thinking)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Advice & Tips: Decided that the fuzzy head feeling from it might not be worth the benefit. I will go off for a few weeks and see if it was making a big emough difference in my pain in hands to warrant going back on.
Cost: $50-99 monthly
Side effects: fuzzy thinking

Jan 12, 2010 (Started Jun 05, 2009)

  • Effectiveness
    Slight (for peripheral neuritis)
  • Side effects
    Mild (fuzzy thinking)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I am weaning off this drug as it doesn't seem to be helping alot
Cost: $50-99 monthly
Side effects: fuzzy thinking

Dec 4, 2009 (Started Jun 05, 2009)

  • Effectiveness
    Slight (for peripheral neuritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: $50-99 monthly
Side effects: fuzzy thinking

Oct 29, 2009 (Started Jun 05, 2009)

  • Effectiveness
    Moderate (for peripheral neuritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: $25-49 monthly
Side effects: fuzzy thinking

Sep 23, 2009 (Started Jun 05, 2009)

  • Effectiveness
    Slight (for peripheral neuritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: $25-49 monthly
Side effects: fuzzy thinking

  • 0 helpful marks

Jul 6, 2016 (Started Aug 08, 2009)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I didn't think Cymbalta helped my pain, so I weaned off of it.  I couldn't believe how much worse my pain was without Cymbalta, so I went back to taking it daily.  I am not sure that it's the best treatment for my depression though!
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 321 patient evaluations for Duloxetine