What is Duloxetine?

Category: Prescription Drugs

Most popular types: Cymbalta Cymgen Yentreve Show all

false

Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 5,345 2,517
Depressed mood 1,869 1,040
Major Depressive Disorder 1,397 822
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 678 359
Generalized Anxiety Disorder 662 471
Pain 504 285

Show all 321 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 787
Moderate 827
Mild 952
None 1,296

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Nausea 245
Weight gain 232
Sex drive (libido) decreased 152
Dizziness 146
Dry mouth 130
Sweating increased 97

Show all 660 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 323
30 mg daily 132
120 mg daily 72
90 mg daily 56
60 mg twice daily 43
20 mg daily 32
30 mg twice daily 25
40 mg daily 18
120 mg twice daily 6
30 mg three times daily 4

See all 42 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1580
Did not seem to work 1345
Doctor's advice 509
Expense 414
Other 379
Personal research 148
Change in health plan coverage 142
Course of treatment ended 61
See all 3064 patients who’ve stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
Less than 1 month 4
1 - 6 months 48
6 months - 1 year 74
1 - 2 years 126
2 - 5 years 207
5 - 10 years 221
10 years or more 82

Stopped taking Duloxetine

Duration Patients
Less than 1 month 656
1 - 6 months 904
6 months - 1 year 493
1 - 2 years 438
2 - 5 years 445
5 - 10 years 118
10 years or more 26
Adherence
Adherence Evaluations
Always 3252
Usually 347
Sometimes 57
Never taken as prescribed 206
Burden
Burden Evaluations
Very hard to take 240
Somewhat hard to take 306
A little hard to take 471
Not at all hard to take 2845
Cost per month
Cost per month Evaluations
$200+ 116
$100-199 171
$50-99 391
$25-49 594
< $25 1151
Not specified 1439

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 78
Venlafaxine (Effexor XR) 64
Fluoxetine (Prozac) 62
Sertraline (Zoloft) 56
Citalopram (Celexa) 50

Show all 55 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Venlafaxine (Effexor XR) 44
Pregabalin (Lyrica) 36
Bupropion (Wellbutrin XL) 25
Gabapentin (Neurontin) 25
Sertraline (Zoloft) 23

Show all 53 treatments patients report switching to

Last updated:

315 patient evaluations for Duloxetine

3,080 members have decided to share their profiles only with other members of PatientsLikeMe.

missgriffith85
50187 thumb
missgriffith85
Gender: F
Data Quality: 1 star
Pain: Some
Fatigue: Some
Sleep: None
Stiffness: Little
function: All
external_stress: Little
Stickman: little
Description:F31y
FM:7y Dx
I am: g
I have:
Fibromyalgia

See missgriffith85's full Duloxetine history

Feb 15, 2016 (Started Apr 06, 2012)

  • Effectiveness
    Slight (for Fibromyalgia)
  • Side effects
    Mild (Dry mouth, Indigestion)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 120 mg Daily
Cost: < $25 monthly

Jan 31, 2016 (Started Apr 06, 2012)

  • Effectiveness
    Major (for Fibromyalgia)
  • Side effects
    Mild (Dry mouth, Indigestion)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 120 mg Daily

May 15, 2013 (Started Apr 06, 2012)

  • Effectiveness
    Major (for Fibromyalgia)
  • Side effects
    Moderate (Dry mouth, Indigestion)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: I took this for Fibromyalgia and it is an SSRI so it lifts you mood a bit after you take it for an extended period of time.
Cost: $200+ monthly

Feb 6, 2013 (Started Apr 06, 2012)

  • Effectiveness
    Can’t tell (for Generalized Anxiety Disorder)
  • Effectiveness
    Moderate (for Fibromyalgia)
  • Side effects
    Mild (Dry mouth, Indigestion)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: $200+ monthly

Dec 11, 2012 (Started Apr 06, 2012)

  • Effectiveness
    Major (for Fibromyalgia)
  • Side effects
    Mild (Dry mouth, Indigestion)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Cost: $200+ monthly

Nov 30, 2012 (Started Apr 06, 2012)

  • Effectiveness
    Moderate (for Fibromyalgia)
  • Side effects
    Mild (Dry mouth, Indigestion)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: It helps with Anxiety.
Cost: $200+ monthly

  • 1 helpful mark
futterfly
78247 thumb
futterfly
Gender: F
Data Quality: 1 star
Depression: 1
Mania: 1
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Moderate
43 F
Function: High
Distress: Low
I am: b
I have:
Bipolar II

See futterfly's full Duloxetine history

Dec 8, 2015 (Started Jul 01, 2014)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Effectiveness
    Major (for Bipolar II Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Advice & Tips: Do not skip doses. If you go more than 2 or 3 days you will start feeling like you have the flu.
Cost: $50-99 monthly

  • 0 helpful marks
vniagara
Portrait default thumb
vniagara
Gender: M
Data Quality: 0 stars
Pain: All
Fatigue: Most
Sleep: Some
Stiffness: All
function: Little
external_stress: Some
Stickman: most
Description:M43y
FM:14y Dx
I have:
Fibromyalgia

See vniagara's full Duloxetine history

Oct 12, 2015 (Started Sep 09, 2010)

  • Effectiveness
    Can’t tell (for Fibromyalgia)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Somewhat hard to take
Dosage: 90 mg Daily
Advice & Tips: Hopefully this medication will help some people with Fibromyalgia however it does not seem to help me at all.

  • 0 helpful marks
Last updated:
Showing 3 of 315 patient evaluations for Duloxetine