What is Duloxetine?

Category: Prescription Drugs

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Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 6,302 3,169
Depressed mood 2,058 1,206
Major depressive disorder 1,875 1,133
Generalized anxiety disorder 789 552
Myalgic encephalomyelitis/chronic fatigue syndrome 696 387
Pain 534 313

Show all 326 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
922
Moderate
1,002
Mild
1,133
None
1,728

Commonly reported side effects and conditions associated with Duloxetine

Side effect Patients
Weight gain 315
Nausea 286
Dry mouth 166
Dizziness 158
Decreased sex drive (libido) 153
Sweating increased 100

Show all 747 reported side effects

Dosages

Based on patients currently taking Duloxetine

Dosage Patients
60 mg daily 441
30 mg daily 183
120 mg daily 126
90 mg daily 79
60 mg twice daily 78
20 mg daily 67
30 mg twice daily 30
40 mg daily 23
20 mg twice daily 13
120 mg twice daily 13

See all 47 dosages

Why patients stopped taking Duloxetine

Multiple reasons could be selected

Reason Patients
Side effects too severe 1740
Did not seem to work 1530
Doctor's advice 579
Expense 444
Other 427
Personal research 169
Change in health plan coverage 159
Course of treatment ended 69
See all 3451 patients who've stopped taking Duloxetine

Duration

Currently taking Duloxetine

Duration Patients
1 - 6 months 53
6 months - 1 year 103
1 - 2 years 167
2 - 5 years 331
5 - 10 years 335
10 years or more 149

Stopped taking Duloxetine

Duration Patients
Less than 1 month 809
1 - 6 months 931
6 months - 1 year 542
1 - 2 years 489
2 - 5 years 511
5 - 10 years 153
10 years or more 33
Adherence
Adherence Evaluations
Always 4006
Usually 423
Sometimes 73
Never taken as prescribed 283
Burden
Burden Evaluations
Very hard to take 299
Somewhat hard to take 365
A little hard to take 559
Not at all hard to take 3562
Cost per month
Cost per month Evaluations
$200+ 126
$100-199 191
$50-99 430
$25-49 686
< $25 1547
Not specified 1805

What people switch to and from

Patients started taking Duloxetine after stopping:

Treatment Patients
Pregabalin (Lyrica) 152
Fluoxetine (Prozac) 125
Venlafaxine (Effexor XR) 121
Sertraline (Zoloft) 108
Citalopram (Celexa) 95

Show all 75 treatments patients report switching from

Patients stopped taking Duloxetine and switched to:

Treatment Patients
Pregabalin (Lyrica) 78
Venlafaxine (Effexor XR) 68
Gabapentin (Neurontin) 58
Escitalopram (Lexapro) 36
Sertraline (Zoloft) 36

Show all 77 treatments patients report switching to

Last updated:

319 patient evaluations for Duloxetine

Jun 17, 2017 (Started Feb 23, 2017)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    Moderate (dizziness, tremor(s))
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Mar 1, 2017 (Started Oct 30, 2013)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Mild (insomnia, headaches, bitter taste, daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

Jul 10, 2016 (Started Oct 30, 2013)

  • Effectiveness
    Can't tell (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Moderate (insomnia, headaches, bitter taste, daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

Jul 7, 2016 (Started Oct 30, 2013)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Mild (insomnia, headaches, bitter taste, daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

Jul 3, 2016 (Started Oct 30, 2013)

  • Effectiveness
    Can't tell (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Mild (daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Cost: < $25 monthly

Nov 2, 2013 (Started Oct 30, 2013)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: $50-99 monthly

Oct 30, 2013 (Started Oct 30, 2013)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Mild (daytime sleepiness, constipation, migraine headaches, gas pain, nausea)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks

Nov 20, 2016 (Started May 15, 2012)

  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (muscle and joint pain, muscle fatigue)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 180 mg Twice daily
Advice & Tips: This medication is habit forming and it’s withdrawal effects took nearly SEVEN MONTHS to wear off! Be careful when you are prescribed this medication..
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 319 patient evaluations for Duloxetine