What is Azathioprine?

Category: Prescription Drugs

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Azathioprine is an immunosuppressant agent used to manage active rheumatoid arthritis and as an adjunctive therapy for the prevention of rejection of kidney transplants.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent organ rejection 126 30
Systemic Lupus Erythematosus 119 47
Crohn's Disease 92 38
Neuromyelitis Optica 58 18
Idiopathic Pulmonary Fibrosis 49 22
Multiple Sclerosis 44 23

Show all 141 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 54
Moderate 67
Mild 68
None 97

Commonly reported side effects and conditions associated with Azathioprine

Side effect Patients
Nausea 24
Hair loss 18
Nausea and vomiting 14
Fatigue 11
Stomach upset 9
Vomiting 9

Show all 149 reported side effects

Dosages

Based on patients currently taking Azathioprine

Dosage Patients
150 mg daily 18
50 mg daily 17
100 mg daily 13
75 mg daily 8
50 mg twice daily 7
100 mg twice daily 5
25 mg daily 3
50 mg three times daily 2
200 mg daily 2
50 mg four times daily 2

See all 17 dosages

Why patients stopped taking Azathioprine

Multiple reasons could be selected

Reason Patients
Doctor's advice 96
Side effects too severe 96
Did not seem to work 65
Other 35
Course of treatment ended 21
Personal research 10
Change in health plan coverage 6
Expense 2
See all 250 patients who’ve stopped taking Azathioprine

Duration

Currently taking Azathioprine

Duration Patients
1 - 6 months 7
6 months - 1 year 12
1 - 2 years 13
2 - 5 years 25
5 - 10 years 16
10 years or more 13

Stopped taking Azathioprine

Duration Patients
Less than 1 month 44
1 - 6 months 57
6 months - 1 year 37
1 - 2 years 38
2 - 5 years 28
5 - 10 years 20
10 years or more 26
Adherence
Adherence Evaluations
Always 245
Usually 24
Sometimes 4
Never taken as prescribed 13
Burden
Burden Evaluations
Very hard to take 11
Somewhat hard to take 9
A little hard to take 51
Not at all hard to take 215
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 3
$50-99 6
$25-49 8
< $25 127
Not specified 139

What people switch to and from

Patients started taking Azathioprine after stopping:

Treatment Patients
Methotrexate (Metoject) 26
Prednisone (Deltasone) 8
Hydroxychloroquine (Plaquenil) 6
Mycophenolate mofetil (CellCept) 6
Leflunomide (Arava) 2

Show all 20 treatments patients report switching from

Patients stopped taking Azathioprine and switched to:

Treatment Patients
Mycophenolate mofetil (CellCept) 11
Methotrexate (Metoject) 6
Cyclophosphamide (Cytoxan) 3
Leflunomide (Arava) 3
Belimumab (Benlysta) 2

Show all 18 treatments patients report switching to

Last updated:

15 patient evaluations for Azathioprine

244 members have decided to share their profiles only with other members of PatientsLikeMe.

kaywile
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kaywile
Data Quality: 1 star
  • Gender: F
  • Age: 54
Condition: Systemic Lupus Erythematosus 12 additional condition(s)
Quality of life:
  • Mental: Severe
  • Physical: Mild
I am: vb
I have:
Systemic Lupus Erythematosus

See kaywile's full Azathioprine history

Nov 15, 2013 (Started Mar 13, 2013)

  • Effectiveness
    Slight (for Systemic Lupus Erythematosus)
  • Effectiveness
    Slight (for Diarrhea chronic)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Advice & Tips: Always listen to your body, if it's aching or sore somewhere, thee is usually a reason for it. Follow up on it and don't let it go.

  • 0 helpful marks
skip47
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skip47
Data Quality: 1 star
  • Sex: M
  • Age: 69y
  • Organ: Kidney
Quality of life:
  • Mental: Mild
  • Physical: Mild
  1. Kidney : 42y Transplanted
I have:
Kidney Transplant

See skip47's full Azathioprine history

Aug 29, 2013 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

Sep 14, 2011 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    Severe (Non-Hodgkin's Lymphoma)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: This treatment had virtually no negative impact on me, with the exception of developing post-transplant lymphoproliferative disorder (lymphoma) over thirty years later. That nearly killed me, but five years passed and I am declared cured, and 37 years after my transplant, my kidney still works well.
Cost: < $25 monthly

Sep 13, 2010 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    Severe (Non-Hodgkin's Lymphoma)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Taking two or three pills for life off of dialysis is a no-brainer. I developed lymphoma as a result of the azathioprine, but the chances of getting this are greater for the newer medications. I was initially worried about infections from this med but it has not been much of a problem.
Cost: < $25 monthly

  • 0 helpful marks
Uncle Buck
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Uncle Buck
Data Quality: 2 stars
  • Sex: M
  • Age: 75y
  • Organ: Heart/Kidney
Quality of life:
  • Mental: Mild
  • Physical: Moderate
  1. Heart : 10y Transplanted
  2. Kidney : 7y Transplanted
I have:
Heart Transplant

See Uncle Buck's full Azathioprine history

Jun 13, 2013 (Started Mar 18, 2009)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    Mild (Night cramps in legs and feet, Loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: $25-49 monthly
Side effects: Night cramps in legs and feet

  • 0 helpful marks
Last updated:
Showing 3 of 15 patient evaluations for Azathioprine