What is Azathioprine?

Category: Prescription Drugs

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Azathioprine is an immunosuppressant agent used to manage active rheumatoid arthritis and as an adjunctive therapy for the prevention of rejection of kidney transplants.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Systemic Lupus Erythematosus 146 65
Prevent organ rejection 126 31
Crohn's Disease 97 41
Neuromyelitis Optica 59 19
Idiopathic Pulmonary Fibrosis 50 23
Multiple Sclerosis 44 23

Show all 142 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 56
Moderate 71
Mild 71
None 112

Commonly reported side effects and conditions associated with Azathioprine

Side effect Patients
Nausea 26
Hair loss 19
Fatigue 14
Nausea and vomiting 14
Vomiting 10
Upset stomach 9

Show all 153 reported side effects

Dosages

Based on patients currently taking Azathioprine

Dosage Patients
150 mg daily 23
50 mg daily 22
50 mg twice daily 20
100 mg daily 13
100 mg twice daily 7
75 mg daily 5
200 mg daily 5
50 mg three times daily 4
125 mg daily 3
25 mg daily 2

See all 21 dosages

Why patients stopped taking Azathioprine

Multiple reasons could be selected

Reason Patients
Doctor's advice 103
Side effects too severe 98
Did not seem to work 70
Other 39
Course of treatment ended 22
Personal research 11
Change in health plan coverage 6
Expense 3
See all 263 patients who’ve stopped taking Azathioprine

Duration

Currently taking Azathioprine

Duration Patients
Less than 1 month 1
1 - 6 months 10
6 months - 1 year 14
1 - 2 years 21
2 - 5 years 37
5 - 10 years 17
10 years or more 18

Stopped taking Azathioprine

Duration Patients
Less than 1 month 45
1 - 6 months 59
6 months - 1 year 40
1 - 2 years 43
2 - 5 years 29
5 - 10 years 21
10 years or more 26
Adherence
Adherence Evaluations
Always 263
Usually 24
Sometimes 7
Never taken as prescribed 16
Burden
Burden Evaluations
Very hard to take 12
Somewhat hard to take 10
A little hard to take 56
Not at all hard to take 232
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 3
$50-99 6
$25-49 11
< $25 139
Not specified 148

What people switch to and from

Patients started taking Azathioprine after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 27
Prednisone (Deltasone) 12
Hydroxychloroquine (Plaquenil) 8
Mycophenolate mofetil (CellCept) 8
Mesalamine (Pentasa) 3

Show all 23 treatments patients report switching from

Patients stopped taking Azathioprine and switched to:

Treatment Patients
Mycophenolate mofetil (CellCept) 13
Methotrexate (Apo-Methotrexate) 8
Hydroxychloroquine (Plaquenil) 4
Prednisone (Deltasone) 4
Cyclophosphamide (Cytoxan) 3

Show all 19 treatments patients report switching to

Last updated:

15 patient evaluations for Azathioprine

265 members have decided to share their profiles only with other members of PatientsLikeMe.

kaywile
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kaywile
Data Quality: 1 star
  • Gender: F
  • Age: 54
Condition: Systemic Lupus Erythematosus 12 additional condition(s)
Quality of life:
  • Mental: Severe
  • Physical: Mild
I am: vb
I have:
Systemic Lupus Erythematosus

See kaywile's full Azathioprine history

Nov 15, 2013 (Started Mar 13, 2013)

  • Effectiveness
    Slight (for Systemic Lupus Erythematosus)
  • Effectiveness
    Slight (for Chronic Diarrhea)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Advice & Tips: Always listen to your body, if it's aching or sore somewhere, thee is usually a reason for it. Follow up on it and don't let it go.

  • 0 helpful marks
skip47
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skip47
Data Quality: 1 star
  • Sex: M
  • Age: 69y
  • Organ: Kidney
Quality of life:
  • Mental: Mild
  • Physical: Mild
  1. Kidney : 42y Transplanted
I have:
Kidney Transplant

See skip47's full Azathioprine history

Aug 29, 2013 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

Sep 14, 2011 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    Severe (Non-Hodgkin's Lymphoma)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: This treatment had virtually no negative impact on me, with the exception of developing post-transplant lymphoproliferative disorder (lymphoma) over thirty years later. That nearly killed me, but five years passed and I am declared cured, and 37 years after my transplant, my kidney still works well.
Cost: < $25 monthly

Sep 13, 2010 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    Severe (Non-Hodgkin's Lymphoma)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Taking two or three pills for life off of dialysis is a no-brainer. I developed lymphoma as a result of the azathioprine, but the chances of getting this are greater for the newer medications. I was initially worried about infections from this med but it has not been much of a problem.
Cost: < $25 monthly

  • 0 helpful marks
Uncle Buck
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Uncle Buck
Data Quality: 1 star
  • Sex: M
  • Age: 75y
  • Organ: Heart/Kidney
Quality of life:
  • Mental: Mild
  • Physical: Mild
  1. Heart : 11y Transplanted
  2. Kidney : 7y Transplanted
I have:
Heart Transplant

See Uncle Buck's full Azathioprine history

Jun 13, 2013 (Started Mar 18, 2009)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for Transplant rejection prevention)
  • Side effects
    Mild (Night cramps in legs and feet, Loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: $25-49 monthly
Side effects: Night cramps in legs and feet

  • 0 helpful marks
Last updated:
Showing 3 of 15 patient evaluations for Azathioprine