What is Azathioprine?

Category: Prescription Drugs

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Azathioprine is an immunosuppressant agent used to manage active rheumatoid arthritis and as an adjunctive therapy for the prevention of rejection of kidney transplants.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Systemic lupus erythematosus 172 78
Prevent organ rejection 126 31
Crohn's disease 109 48
Neuromyelitis optica 58 18
Idiopathic pulmonary fibrosis 52 24

Show all 129 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 61
Moderate 74
Mild 78
None 130

Commonly reported side effects and conditions associated with Azathioprine

Side effect Patients
Nausea 27
Hair loss 20
Fatigue 17
Nausea and vomiting 14
Upset stomach 10
Vomiting 10

Show all 162 reported side effects

Dosages

Based on patients currently taking Azathioprine

Dosage Patients
100 mg daily 24
50 mg daily 20
150 mg daily 16
50 mg twice daily 11
75 mg daily 7
50 mg three times daily 7
25 mg daily 6
125 mg daily 3
100 mg twice daily 3
150 mg three times daily 3

See all 24 dosages

Why patients stopped taking Azathioprine

Multiple reasons could be selected

Reason Patients
Doctor's advice 115
Side effects too severe 107
Did not seem to work 77
Other 42
Course of treatment ended 25
Personal research 11
Change in health plan coverage 6
Expense 3
See all 287 patients who've stopped taking Azathioprine

Duration

Currently taking Azathioprine

Duration Patients
Less than 1 month 1
1 - 6 months 11
6 months - 1 year 8
1 - 2 years 18
2 - 5 years 31
5 - 10 years 22
10 years or more 25

Stopped taking Azathioprine

Duration Patients
Less than 1 month 50
1 - 6 months 62
6 months - 1 year 46
1 - 2 years 46
2 - 5 years 32
5 - 10 years 25
10 years or more 26
Adherence
Adherence Evaluations
Always 291
Usually 27
Sometimes 7
Never taken as prescribed 18
Burden
Burden Evaluations
Very hard to take 12
Somewhat hard to take 14
A little hard to take 59
Not at all hard to take 258
Cost per month
Cost per month Evaluations
$200+ 4
$100-199 3
$50-99 7
$25-49 12
< $25 148
Not specified 169

What people switch to and from

Patients started taking Azathioprine after stopping:

Treatment Patients
Methotrexate (Apo-Methotrexate) 31
Prednisone (Deltasone) 14
Mycophenolate mofetil (CellCept) 11
Hydroxychloroquine (Plaquenil) 8
Leflunomide (Arava) 4

Show all 26 treatments patients report switching from

Patients stopped taking Azathioprine and switched to:

Treatment Patients
Mycophenolate mofetil (CellCept) 14
Methotrexate (Apo-Methotrexate) 10
Hydroxychloroquine (Plaquenil) 5
Prednisone (Deltasone) 4
Adalimumab (Humira) 3

Show all 21 treatments patients report switching to

Last updated:

15 patient evaluations for Azathioprine

Nov 15, 2013 (Started Mar 13, 2013)

  • Effectiveness
    Slight (for systemic lupus erythematosus)
  • Effectiveness
    Slight (for chronic diarrhea)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Advice & Tips: Always listen to your body, if it's aching or sore somewhere, thee is usually a reason for it. Follow up on it and don't let it go.

  • 0 helpful marks

Aug 29, 2013 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for transplant rejection prevention)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

Sep 14, 2011 (Started Sep 06, 1974)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for transplant rejection prevention)
  • Side effects
    Severe (non-Hodgkin's lymphoma)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: This treatment had virtually no negative impact on me, with the exception of developing post-transplant lymphoproliferative disorder (lymphoma) over thirty years later. That nearly killed me, but five years passed and I am declared cured, and 37 years after my transplant, my kidney still works well.
Cost: < $25 monthly

Sep 13, 2010 (Started Sep 06, 1974)

  • Effectiveness
    Major (for transplant rejection prevention)
  • Side effects
    Severe (non-Hodgkin's lymphoma)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Taking two or three pills for life off of dialysis is a no-brainer. I developed lymphoma as a result of the azathioprine, but the chances of getting this are greater for the newer medications. I was initially worried about infections from this med but it has not been much of a problem.
Cost: < $25 monthly

  • 0 helpful marks

Jun 13, 2013 (Started Mar 18, 2009)

  • Effectiveness
    Major (for Prevent organ rejection)
  • Effectiveness
    Major (for transplant rejection prevention)
  • Side effects
    Mild (night cramps in legs and feet, loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: $25-49 monthly
Side effects: night cramps in legs and feet

  • 0 helpful marks
Last updated:
Showing 3 of 15 patient evaluations for Azathioprine