Vitamin B12 deficiency

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What is vitamin B12 deficiency?

Vitamin B12, a water soluble vitamin, helps in the formation of red blood cells and in the maintenance of the central nervous system. Deficiency is due to inadequate dietary intake or impaired absorption of Vitamin B12 resulting in megaloblastic anemia due to inhibition in red blood cell production.

Common symptoms reported by people with vitamin B12 deficiency

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
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Treatments taken by people with vitamin B12 deficiency

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(NatureMade Vitamin B12)
Type
Supplement
How many have tried
87
Tried for
vitamin B12 deficiency (87) Fatigue (3)
Treatment name(s)

(Medivitan)
Type
Prescription Drug
How many have tried
49
Tried for
vitamin B12 deficiency (48) Fatigue (7)
Treatment name(s)

(Folic Acid Prescription)
Type
Supplement
How many have tried
29
Tried for
vitamin B12 deficiency (29)
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
20
Tried for
Pain (20)
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
19
Tried for
Pain (17) Depressed mood (1)
1 more
Treatment name(s)

(Norco)
Type
Prescription Drug
How many have tried
17
Tried for
Pain (17)
Treatment name(s)

(Desyrel)
Type
Prescription Drug
How many have tried
15
Tried for
Insomnia (15) Depressed mood (1)
Treatment name(s)

(Nature's Bounty Melatonin)
Type
Supplement
How many have tried
14
Tried for
Insomnia (14)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
12
Tried for
Depressed mood (10) Pain (2)
Treatment name(s)

(Remeron)
Type
Prescription Drug
How many have tried
11
Tried for
Insomnia (11) Depressed mood (5)

Data from patients with vitamin B12 deficiency, who reported starting treatments within the last 5 years.
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Compare treatments taken by people with vitamin B12 deficiency

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(NatureMade Vitamin B12)
Perceived effectiveness
for vitamin B12 deficiency (31 evaluations)
Side effects
Bruising Diarrhea 1 more
Total evaluations
36
Tried for
vitamin B12 deficiency (87) Fatigue (3)
Treatment name(s)

(Medivitan)
Perceived effectiveness
for vitamin B12 deficiency (35 evaluations)
Side effects
Headaches Injection site bruising
Total evaluations
37
Tried for
vitamin B12 deficiency (48) Fatigue (7)
Treatment name(s)

(Folic Acid Prescription)
Perceived effectiveness
for vitamin B12 deficiency (4 evaluations)
Side effects
Total evaluations
5
Tried for
vitamin B12 deficiency (29)
Treatment name(s)

(Ultram)
Perceived effectiveness
for Pain (13 evaluations)
Side effects
Nausea Allergic reaction 7 more
Total evaluations
13
Tried for
Pain (20)
Treatment name(s)

(Neurontin)
Perceived effectiveness
for Pain (13 evaluations)
Side effects
Sleepiness Anxious mood 12 more
Total evaluations
18
Tried for
Pain (17) Depressed mood (1)
1 more
Treatment name(s)

(Norco)
Perceived effectiveness
for Pain (6 evaluations)
Side effects
Chronic constipation Constipation
Total evaluations
6
Tried for
Pain (17)
Treatment name(s)

(Desyrel)
Perceived effectiveness
for Insomnia (3 evaluations)
Side effects
Drugged feeling
Total evaluations
3
Tried for
Insomnia (15) Depressed mood (1)
Treatment name(s)

(Nature's Bounty Melatonin)
Perceived effectiveness
for Insomnia (6 evaluations)
Side effects
Drowsiness Tiredness
Total evaluations
6
Tried for
Insomnia (14)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for Depressed mood (4 evaluations)
Side effects
Anger Brain zaps 3 more
Total evaluations
7
Tried for
Depressed mood (10) Pain (2)
Treatment name(s)

(Remeron)
Perceived effectiveness
for Insomnia (5 evaluations)
Side effects
Excessive daytime sleepiness (somnolence) Fatigue 6 more
Total evaluations
10
Tried for
Insomnia (11) Depressed mood (5)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with vitamin B12 deficiency, who reported starting treatments within the last 5 years.
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Who has vitamin B12 deficiency on PatientsLikeMe?


Age
Age Proportion # of patients
<20 2
20s 58
30s 147
40s 305
50s 284
60s 124
70+ 34
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 36
20-29 years 77
30-39 years 117
40-49 years 101
50-59 years 47
60-69 years 6
70+ years 2

Sex

Distribution of sex

87% Female
13% Male

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 549
Not Diagnosed 27

These charts show data from vitamin B12 deficiency patients who have completed their condition history
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