Vitamin B12 deficiency

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What is vitamin B12 deficiency?

Vitamin B12, a water soluble vitamin, helps in the formation of red blood cells and in the maintenance of the central nervous system. Deficiency is due to inadequate dietary intake or impaired absorption of Vitamin B12 resulting in megaloblastic anemia due to inhibition in red blood cell production.

Common symptoms reported by people with vitamin B12 deficiency

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people with vitamin B12 deficiency

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(NatureMade Vitamin B12)
Type
Supplement
How many have tried
88
Tried for
vitamin B12 deficiency (88) fatigue (3)
Treatment name(s)

(Medivitan)
Type
Prescription Drug
How many have tried
48
Tried for
vitamin B12 deficiency (46) fatigue (8)
Treatment name(s)

(Folic Acid Prescription)
Type
Supplement
How many have tried
25
Tried for
vitamin B12 deficiency (25)
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
18
Tried for
pain (18)
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
17
Tried for
pain (16) depressed mood (1)
Treatment name(s)

(Norco)
Type
Prescription Drug
How many have tried
16
Tried for
pain (16)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
12
Tried for
depressed mood (9) pain (3)
Treatment name(s)

(Vistaril)
Type
Prescription Drug
How many have tried
10
Tried for
anxious mood (10)
Treatment name(s)

(Zoloft)
Type
Prescription Drug
How many have tried
10
Tried for
depressed mood (10) anxious mood (1)
Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
8
Tried for
pain (7) depressed mood (1)

Data from patients with vitamin B12 deficiency, who reported starting treatments within the last 5 years.
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Compare treatments taken by people with vitamin B12 deficiency

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(NatureMade Vitamin B12)
Perceived effectiveness
for vitamin B12 deficiency (29 evaluations)
Side effects
diarrhea
Total evaluations
33
Tried for
vitamin B12 deficiency (88) fatigue (3)
Treatment name(s)

(Medivitan)
Perceived effectiveness
for vitamin B12 deficiency (33 evaluations)
Side effects
headaches
Total evaluations
35
Tried for
vitamin B12 deficiency (46) fatigue (8)
Treatment name(s)

(Folic Acid Prescription)
Perceived effectiveness
for vitamin B12 deficiency (3 evaluations)
Side effects
Total evaluations
4
Tried for
vitamin B12 deficiency (25)
Treatment name(s)

(Ultram)
Perceived effectiveness
for pain (12 evaluations)
Side effects
nausea allergic reaction 7 more
Total evaluations
12
Tried for
pain (18)
Treatment name(s)

(Neurontin)
Perceived effectiveness
for pain (14 evaluations)
Side effects
sleepiness anxious mood 12 more
Total evaluations
17
Tried for
pain (16) depressed mood (1)
Treatment name(s)

(Norco)
Perceived effectiveness
for pain (7 evaluations)
Side effects
chronic constipation constipation
Total evaluations
7
Tried for
pain (16)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for depressed mood (4 evaluations)
Side effects
anger brain zaps 5 more
Total evaluations
8
Tried for
depressed mood (9) pain (3)
Treatment name(s)

(Vistaril)
Perceived effectiveness
for anxious mood (3 evaluations)
Side effects
daytime sleepiness excessive daytime sleepiness (somnolence)
Total evaluations
3
Tried for
anxious mood (10)
Treatment name(s)

(Zoloft)
Perceived effectiveness
for depressed mood (8 evaluations)
Side effects
weight gain apathy 3 more
Total evaluations
11
Tried for
depressed mood (10) anxious mood (1)
Treatment name(s)

(Elavil)
Perceived effectiveness
for pain (5 evaluations)
Side effects
weight gain increased pain
Total evaluations
6
Tried for
pain (7) depressed mood (1)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with vitamin B12 deficiency, who reported starting treatments within the last 5 years.
Last updated:

Who has vitamin B12 deficiency on PatientsLikeMe?


Age
Age Proportion # of patients
<20 3
20s 54
30s 152
40s 322
50s 299
60s 141
70+ 38
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 36
20-29 years 79
30-39 years 121
40-49 years 101
50-59 years 49
60-69 years 6
70+ years 2

Sex

Distribution of sex

87% Female
13% Male

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 562
Not Diagnosed 28

These charts show data from vitamin B12 deficiency patients who have completed their condition history
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