What is Estriol topical?

Category: Prescription Drugs

Most popular types: Ovestin creme (Oestriol)

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See also: Bi-Est

Estriol (also oestriol) is one of the three main estrogens produced by the human body. It is only produced in significant amounts during pregnancy as it is made by the placenta. It is used in hormone therapy.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 16 11
Hormone replacement 7 2
Hormonal imbalance 2 1
Participate in clinical trial 2 1
Support hormone balance 2 0
Vaginal Atrophy 2 2

Show all 14 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 2
Moderate 1
Mild 2
None 13

Commonly reported side effects and conditions associated with Estriol topical

Side effect Patients
Irregular menstrual periods 1
Menses cycle altered 1
migraine 1

Dosages

Based on patients currently taking Estriol topical

Dosage Patients
1 mg m,w,f 1
3 mg daily 1
8 mg daily 1
15 mg daily 1
1app as needed 1

Why patients stopped taking Estriol topical

Multiple reasons could be selected

Reason Patients
Other 5
Did not seem to work 2
Course of treatment ended 1
Expense 1
Side effects too severe 1
See all 10 patients who've stopped taking Estriol topical

Duration

Currently taking Estriol topical

Duration Patients
1 - 2 years 1
2 - 5 years 1
5 - 10 years 3

Stopped taking Estriol topical

Duration Patients
1 - 6 months 1
6 months - 1 year 1
1 - 2 years 5
2 - 5 years 2
10 years or more 1
Adherence
Adherence Evaluations
Always 15
Usually 3
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 2
A little hard to take 0
Not at all hard to take 14
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 2
$25-49 3
< $25 7
Not specified 6
Last updated:

3 patient evaluations for Estriol topical

Apr 15, 2012 (Started Nov 15, 2009)

  • Effectiveness
    Can’t tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 6 mg Daily
Cost: $25-49 monthly
Side effects: Menses cycle altered

Aug 12, 2010 (Started Nov 15, 2009)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (Menses cycle altered)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg Daily
Advice & Tips: I've been on estriol and Copax since late summer/early fall last year and I've been relapse-free since 10/09. Prior to Copax and estriol, I had fresh attacks every 2-3 months from 2/09 on. Recent MRI shows no new or enhancing lesions.
Cost: $25-49 monthly
Side effects: Menses cycle altered

Apr 19, 2010 (Started Nov 15, 2009)

  • Effectiveness
    Can’t tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg Daily
Advice & Tips: Keep in mind I've been taking this with Copaxone and vitamin D3. However, I ran out of estriol for a week and towards the end of the week my symptoms felt more pronounced. Could it have been due to decreased estriol or natural hormonal fluctuations? I don't know but I'm pretty darn careful about taking it just in case. Since beginning the cocktail of Copax., vitamin D3, and estriol, my attacks have abated significantly. Prior to the meds/supplements, I had been having significant attacks roughly every two to three months and I entertained the very real possibility that I would end 2009 in a wheelchair.
Cost: $25-49 monthly
Side effects: Menses cycle altered

  • 4 helpful marks

Jul 1, 2011 (Started Oct 01, 2010)

  • Effectiveness
    None (for Hormone replacement)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 8 mg Daily

  • 0 helpful marks

Apr 15, 2010 (Started Jan 15, 2006)

  • Effectiveness
    Major (for Bladder problems)
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 8 mg Daily
Advice & Tips: I believe it really triggered fibroid tumor growth which is now causing problems.

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Estriol topical