What is Florinef?

Category: Prescription Drugs

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Generic name: Fludrocortisone

Florinef® is a brand name for fludrocortisone, a synthetic corticosteroid used primarily to replace the missing hormone aldosterone in various forms of adrenal insufficiency such as Addison's disease and congenital adrenal hyperplasia. It is the first line of treatment for orthostatic intolerance.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Postural orthostatic tachycardia syndrome 17 13
Orthostatic postural hypotension 15 10
Addison's disease 7 4
Orthostatic hypotension 6 7
Multiple system atrophy 5 5

Show all 26 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
4
Moderate
7
Mild
5
None
17

Commonly reported side effects and conditions associated with Florinef

Side effect Patients
Weight gain 4
Dry mouth 2
Abdominal bloating 1
Abdominal cramps 1
Edema (fluid retention) 1
Elevated blood sugar (hyperglycemia) 1

Show all 15 reported side effects

Dosages

Based on patients currently taking Florinef

Dosage Patients
0.1 mg daily 2
0.05 mg daily 1
0.05 mg twice daily 1
0.15 mg daily 1
0.2 mg daily 1
0.2 mg twice daily 1
100 mcg three times daily 1
0.1mg as needed 1

Why patients stopped taking Florinef

Multiple reasons could be selected

Reason Patients
Side effects too severe 6
Did not seem to work 5
Doctor's advice 4
Personal research 3
Course of treatment ended 2
Other 2
See all 16 patients who've stopped taking Florinef

Duration

Currently taking Florinef

Duration Patients
1 - 6 months 1
2 - 5 years 5
10 years or more 3

Stopped taking Florinef

Duration Patients
Less than 1 month 5
1 - 6 months 3
6 months - 1 year 4
1 - 2 years 1
2 - 5 years 1
5 - 10 years 2
Adherence
Adherence Evaluations
Always 31
Usually 2
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 0
A little hard to take 1
Not at all hard to take 32
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 0
$25-49 1
< $25 18
Not specified 14

What people switch to and from

Patients started taking Florinef after stopping:

Treatment Patients
Midodrine (ProAmatine) 2

Patients stopped taking Florinef and switched to:

Treatment Patients
Droxidopa (Northera) 1
Irbesartan (Avapro) 1
Midodrine (ProAmatine) 1
Last updated:

3 patient evaluations for Florinef

Feb 22, 2010 (Started )

  • Effectiveness
    Moderate (for orthostatic hypotention)
  • Side effects
    Mild (acne breakout)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Side effects: acne breakout

  • 0 helpful marks

Sep 5, 2009 (Started Jul 17, 2009)

  • Effectiveness
    Slight (for orthostatic postural hypotension)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.1 mg Daily

  • 0 helpful marks

Apr 15, 2009 (Started Apr 15, 1998)

  • Effectiveness
    Major (for low blood pressure)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.1 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Florinef