What is Peginterferon alfa 2a?

Category: Prescription Drugs

Most popular types: Pegasys

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Pegylated interferon (peginterferon) alfa-2a is used for the treatment of hepatitis C in a once-a-week injection that works to reduce the amount of hepatitis C virus in the body. It is often used in combination with ribavirin.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Hepatitis C 12 9
Hepatitis B 9 5
Polycythemia vera 2 1
Essential thrombocythemia 1 1
Lymphangiomatosis 1 0

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 5
Moderate 5
Mild 2
None 2

Commonly reported side effects and conditions associated with Peginterferon alfa 2a

Side effect Patients
Neutropenia (low neutrophils) 3
Depressed mood 2
Fever 2
Hair loss 2
Muscle fatigue 2
Nausea and vomiting 2

Show all 19 reported side effects

Dosages

Based on patients currently taking Peginterferon alfa 2a

Dosage Patients
180 mcg weekly 1

Why patients stopped taking Peginterferon alfa 2a

Multiple reasons could be selected

Reason Patients
Course of treatment ended 5
Side effects too severe 5
Did not seem to work 4
Doctor's advice 1
Expense 1
Other 1
See all 15 patients who've stopped taking Peginterferon alfa 2a

Duration

Currently taking Peginterferon alfa 2a

Duration Patients
5 - 10 years 1

Stopped taking Peginterferon alfa 2a

Duration Patients
1 - 6 months 6
6 months - 1 year 5
1 - 2 years 3
2 - 5 years 1
Adherence
Adherence Evaluations
Always 13
Usually 0
Sometimes 0
Never taken as prescribed 1
Burden
Burden Evaluations
Very hard to take 5
Somewhat hard to take 2
A little hard to take 1
Not at all hard to take 6
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 1
$50-99 0
$25-49 1
< $25 4
Not specified 8

What people switch to and from

Patients started taking Peginterferon alfa 2a after stopping:

Treatment Patients
Lamivudine (Epivir) 1
Last updated:

3 patient evaluations for Peginterferon alfa 2a

Jan 28, 2010 (Started Nov 26, 2009)

  • Effectiveness
    Can't tell (for hepatitis C)
  • Side effects
    Moderate (depression with anxiety, depressed mood)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 1 mg Weekly
Cost: < $25 monthly
Side effects: depression with anxiety, depressed mood, depressed mood

  • 0 helpful marks

Nov 24, 2009 (Started Dec 02, 2008)

  • Effectiveness
    Major (for hepatitis C)
  • Side effects
    Mild (nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 180 mcg Weekly
Advice & Tips: Drink lots of water. It keeps the side effects away.
Side effects: nausea and vomiting

  • 0 helpful marks

Jun 1, 2009 (Started Apr 01, 2008)

  • Effectiveness
    None (for hepatitis B)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: Daily
Cost: < $25 monthly
Side effects: hair loss, fever, dry skin, thrombocytopenia (low platelet count), neutropenia (low neutrophils)

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Peginterferon alfa 2a