What is Amitriptyline?

Category: Prescription Drugs

Most popular types: Elavil Endep Trepiline Show all

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Amitriptyline is a tricyclic antidepressant approved for the treatment of depression. Off label amitripyline is used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 1,009 642
Fibromyalgia 929 538
Pain 876 549
Depressed mood 195 112
Migraine headaches 158 102
Sleep problems 152 83

Show all 315 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 257
Moderate 376
Mild 497
None 624

Commonly reported side effects and conditions associated with Amitriptyline

Side effect Patients
Dry mouth 169
Weight gain 103
Drowsiness 73
Sleepiness 56
Excessive daytime sleepiness (somnolence) 47
Grogginess 45

Show all 315 reported side effects

Dosages

Based on patients currently taking Amitriptyline

Dosage Patients
25 mg daily 91
10 mg daily 76
50 mg daily 76
20 mg daily 32
75 mg daily 30
100 mg daily 29
30 mg daily 16
150 mg daily 9
10 mg twice daily 5
40 mg daily 5

See all 34 dosages

Why patients stopped taking Amitriptyline

Multiple reasons could be selected

Reason Patients
Did not seem to work 454
Side effects too severe 445
Doctor's advice 244
Other 163
Course of treatment ended 54
Personal research 51
Expense 15
Change in health plan coverage 11
See all 1060 patients who’ve stopped taking Amitriptyline

Duration

Currently taking Amitriptyline

Duration Patients
Less than 1 month 1
1 - 6 months 33
6 months - 1 year 37
1 - 2 years 55
2 - 5 years 127
5 - 10 years 84
10 years or more 72

Stopped taking Amitriptyline

Duration Patients
Less than 1 month 190
1 - 6 months 295
6 months - 1 year 174
1 - 2 years 143
2 - 5 years 170
5 - 10 years 58
10 years or more 36
Adherence
Adherence Evaluations
Always 1398
Usually 220
Sometimes 69
Never taken as prescribed 67
Burden
Burden Evaluations
Very hard to take 79
Somewhat hard to take 113
A little hard to take 229
Not at all hard to take 1333
Cost per month
Cost per month Evaluations
$200+ 7
$100-199 3
$50-99 9
$25-49 37
< $25 903
Not specified 795

What people switch to and from

Patients started taking Amitriptyline after stopping:

Treatment Patients
Gabapentin (Neurontin) 13
Duloxetine (Cymbalta) 9
Trazodone (Desyrel) 8
Pregabalin (Lyrica) 6
Topiramate (Topamax) 5

Show all 52 treatments patients report switching from

Patients stopped taking Amitriptyline and switched to:

Treatment Patients
Nortriptyline (Pamelor) 20
Gabapentin (Neurontin) 18
Pregabalin (Lyrica) 13
Duloxetine (Cymbalta) 11
Trazodone (Desyrel) 7

Show all 49 treatments patients report switching to

Last updated:

154 patient evaluations for Amitriptyline

1,264 members have decided to share their profiles only with other members of PatientsLikeMe.

donhing
154 thumb
donhing
Sex: M
Data Quality: 3 stars
Bulbar: severe
Arms: severe
Chest: severe
Legs: severe
I am: g
I have:
ALS

See donhing's full Amitriptyline history

Jan 20, 2017 (Started Nov 01, 2007)

  • Effectiveness
    Major (for Excess saliva)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily

  • 0 helpful marks
Ronnell0053
63555 thumb
Ronnell0053
Gender: M
Data Quality: 3 stars
Mental Symptoms : none
Physical Symptoms : none
985
VL 38
I am: vg
I have:
HIV

See Ronnell0053's full Amitriptyline history

Jan 11, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As an Ischemic Stroke survivor and current update &/or physically evaluated patient as required by my HIV Doctor during my every 90 days scheduled appointment, the benefit of Amitriptyline whether expected or not is the overall elimination of the numbness and tingling I use to experience prior to having been prescribed this drug, of which I'd give serious suggestive use of this drug to anyone experiencing numbness and/or tingling in their extremities, whether it's related to HIV or any other medical condition thus causing such an uncomfortable, concern warranting issue.
Cost: < $25 monthly

Jul 14, 2016 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for Peripheral Neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: As with all medicinal treatments, in order to achieve the best results, follow directions as prescribed and allow the medicine up to two weeks before being effective.
Cost: < $25 monthly

  • 0 helpful marks
sheronemus
8881 thumb
sheronemus
Sex: M
Data Quality: 2 stars
Bulbar: moderate
Arms: severe
Chest: moderate
Legs: mild
I am: vg
I have:
ALS

See sheronemus's full Amitriptyline history

Oct 10, 2016 (Started Jul 01, 2009)

  • Effectiveness
    Moderate (for Excess saliva)
  • Side effects
    Mild (Drowsiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 154 patient evaluations for Amitriptyline