What is Prednisone?

Category: Prescription Drugs

Most popular types: Deltasone Prednisone Intensol Encorton Show all

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Prednisone is a synthetic corticosteroid drug that decreases inflammation and suppresses the immune system. It is used for many purposes including relapses in MS, for rheumatic disorders, neoplasms, and collagen diseases. Prednisone is activated by the liver into prednisolone.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Systemic Lupus Erythematosus 1,103 341
Asthma 357 178
Multiple Sclerosis 267 147
Rheumatoid Arthritis (RA) 251 117
Transplant rejection prevention 193 64
COPD (Chronic Obstructive Pulmonary Disease) 134 78

Show all 529 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 404
Moderate 568
Mild 428
None 325

Commonly reported side effects and conditions associated with Prednisone

Side effect Patients
Weight gain 393
Increased appetite 105
Insomnia 80
Mood swings 68
Moon face 60
Insomnia 49

Show all 557 reported side effects

Dosages

Based on patients currently taking Prednisone

Dosage Patients
5 mg daily 80
10 mg daily 69
20 mg daily 32
15 mg daily 21
30 mg daily 20
40 mg daily 15
50 mg daily 14
60 mg daily 13
2.5 mg daily 9
5 mg twice daily 9

See all 86 dosages

Why patients stopped taking Prednisone

Multiple reasons could be selected

Reason Patients
Course of treatment ended 1118
Doctor's advice 446
Side effects too severe 335
Did not seem to work 145
Other 127
Personal research 44
Change in health plan coverage 10
Expense 7
See all 1788 patients who’ve stopped taking Prednisone

Duration

Currently taking Prednisone

Duration Patients
1 - 6 months 40
6 months - 1 year 60
1 - 2 years 75
2 - 5 years 98
5 - 10 years 95
10 years or more 73

Stopped taking Prednisone

Duration Patients
Less than 1 month 753
1 - 6 months 396
6 months - 1 year 178
1 - 2 years 147
2 - 5 years 151
5 - 10 years 77
10 years or more 89
Adherence
Adherence Evaluations
Always 1486
Usually 114
Sometimes 55
Never taken as prescribed 70
Burden
Burden Evaluations
Very hard to take 117
Somewhat hard to take 170
A little hard to take 280
Not at all hard to take 1158
Cost per month
Cost per month Evaluations
$200+ 6
$100-199 7
$50-99 24
$25-49 49
< $25 899
Not specified 740

What people switch to and from

Patients started taking Prednisone after stopping:

Treatment Patients
Hydroxychloroquine (Plaquenil) 13
Methotrexate (Apo-Methotrexate) 11
Methylprednisolone (Solu-Medrol Infusion) 8
Hydrocortisone (Cortef) 5
Azathioprine (Imuran) 4

Show all 32 treatments patients report switching from

Patients stopped taking Prednisone and switched to:

Treatment Patients
Hydroxychloroquine (Plaquenil) 28
Methotrexate (Apo-Methotrexate) 15
Mycophenolate mofetil (CellCept) 11
Methylprednisolone (Solu-Medrol Infusion) 9
Azathioprine (Imuran) 6

Show all 44 treatments patients report switching to

Last updated:

117 patient evaluations for Prednisone

1,305 members have decided to share their profiles only with other members of PatientsLikeMe.

slowrambler
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slowrambler
Sex: M
Data Quality: 2 stars
Relapse: Moderate
Sensation: Severe
Overall: Mild
Cognition: none
Vision: none
Speech: none
Swallowing: none
Upper limb: none
Walking: severe
I am: b
I have:
MS

See slowrambler's full Prednisone history

Mar 5, 2017 (Started Jun 28, 2007)

  • Effectiveness
    Can’t tell (for Relapse MS (exacerbation))
  • Side effects
    Severe (Digestive disturbances)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: $50-99 monthly
Side effects: Digestive disturbances

Feb 5, 2017 (Started Jun 28, 2007)

  • Effectiveness
    Major (for Relapse MS (exacerbation))
  • Side effects
    Moderate (Digestive disturbances)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: I've totally discontinued using the oral prednisone taper following solu-medrol infusions. It's a drag for 3/4 days of feeling wiped out & some other unpleasant after effects. But over many yrs. I've found that enduring the let down & subsequent withdrawal from the high dose infusions has FOR ME been a much better path to follow. MY EXPERIENCE has been that the sooner I can rid myself of the 'roids, the sooner I begin to feel stronger physically, mentally, & emotionally. I can begin PT & working on my overall functionality much sooner absent my body having to fight with lingering steroid effects.
Cost: $50-99 monthly
Side effects: Digestive disturbances

Sep 7, 2012 (Started Jun 28, 2007)

  • Effectiveness
    Can’t tell (for Other)
  • Side effects
    Moderate (Digestive disturbances)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I only take this med as an oral taper after receiving IV solu-medrol. I don't always ask for a taper following IV treatment.
Cost: $50-99 monthly
Side effects: Digestive disturbances

Feb 9, 2009 (Started Jun 28, 2007)

  • Effectiveness
    Moderate (for Other)
  • Side effects
    Severe (Digestive disturbances)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Use only what you need to bring you down from the massive steroid amount received from your infusion. I've found that the quicker I can rid myself of all of the steroids, including the oral taper, the quicker I am on to recovery from the exacerbation.
Cost: $50-99 monthly
Side effects: Digestive disturbances

Sep 7, 2008 (Started Jun 28, 2007)

  • Effectiveness
    Slight (for Other)
  • Side effects
    Severe (Digestive disturbances)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I feel that this medication is good to have available when tapering off of steroids following a regimen of IV solu-medrol. However I find personally that the sooner I can COMPLETELY rid myself of all steroids, the quicker I recover, & the better off I am overall. I like to have the oral Prednisone taper available following infusion as a "safety net" if I need it. Most often I use it for 2 to 3 days. Then I discontinue using it when I feel that my body's no longer craving the high dose of steroid that solu-medrol provides. I have no doubt that using an oral Prednisone taper is highly subjective & individually exclusive in terms of effectiveness to each patient.
Cost: < $25 monthly
Side effects: Digestive disturbances

  • 3 helpful marks
25yrRA
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25yrRA
Data Quality: 1 star
  • Gender: F
  • Age: 55
Condition: Rheumatoid Arthritis (RA) 20 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: n
I have:
Rheumatoid Arthritis (RA)

See 25yrRA's full Prednisone history

Aug 15, 2016 (Started Jan 01, 1985)

  • Effectiveness
    Moderate (for Rheumatoid Arthritis (RA))
  • Effectiveness
    Major (for Addison's Disease)
  • Side effects
    Moderate (Diabetes Type 2, Acute Renal Failure, Weight gain, Irritability)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Prednisone has long (30 years worth) been my "nasty but necessary" treatment for my Rheumatoid Arthritis. It has caused me innumerable side effect problems, including 100lbs of weight gain, the dissolution of my previous marriage, Diabetes II, renal (kidney) failure, etc... Going off of it at various times has made me extremely ill, at least 3 times resulted in my hospitalization. For many years, this was the only RA treatment that functioned consistently and allowed me to continue living my life at least somewhat normally.
Cost: < $25 monthly

  • 0 helpful marks
CarynH
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CarynH
Data Quality: 1 star
  • Gender: F
  • Age: 44
Condition: Crohn's Disease 7 additional condition(s)
Quality of life:
  • Mental: Moderate
  • Physical: Moderate
I am: b
I have:
Crohn's Disease

See CarynH's full Prednisone history

Jul 21, 2016 (Started Sep 15, 2015)

  • Effectiveness
    Slight (for Inflammation in joints)
  • Effectiveness
    Moderate (for Crohn's Disease)
  • Effectiveness
    Moderate (for Arthritis pain)
  • Side effects
    Severe (Insomnia (less than 2 hours sleep), Excessive thirst (polydipsia), Dry skin, Mood swings, Weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: This is low cost but the side effects are worth considering. For short term use not an issue. For long term however, it has weight gain and insomnia, anxiousness, and need to taper of slowly or major withdrawals an issue. It seems for me it is no longer as effective from long term use.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 117 patient evaluations for Prednisone