Mixed connective tissue disease

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What is mixed connective tissue disease?

Mixed connective tissue disease is an uncommon autoimmune disorder that causes overlapping features of primarily three connective tissue diseases: lupus, scleroderma and polymyositis. It may be preceded by Raynaud's phenomenon and have features of rheumatoid arthritis.

Common symptoms reported by people with mixed connective tissue disease

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people with mixed connective tissue disease

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Plaquenil)
Type
Prescription Drug
How many have tried
55
Treatment name(s)

(Deltasone)
Type
Prescription Drug
How many have tried
20
Treatment name(s)

(Trexall)
Type
Prescription Drug
How many have tried
16
Treatment name(s)

(Folic Acid Prescription)
Type
Supplement
How many have tried
14
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
11
Tried for
pain (11)
Treatment name(s)

(Naproxen Prescription)
Type
Over the Counter Drug
How many have tried
8
Treatment name(s)

(Flexeril)
Type
Prescription Drug
How many have tried
6
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
6
Tried for
pain (6)
Treatment name(s)

(Wellbutrin XL)
Type
Prescription Drug
How many have tried
4
Tried for
depressed mood (4)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
4

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
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Compare treatments taken by people with mixed connective tissue disease

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Plaquenil)
Perceived effectiveness
for mixed connective tissue disease (20 evaluations)
Side effects
nausea dizziness 7 more
Total evaluations
23
Treatment name(s)

(Deltasone)
Perceived effectiveness
for mixed connective tissue disease (9 evaluations)
Side effects
headaches moodiness 17 more
Total evaluations
17
Treatment name(s)

(Trexall)
Perceived effectiveness
for mixed connective tissue disease (6 evaluations)
Side effects
fatigue nausea 9 more
Total evaluations
12
Treatment name(s)

(Folic Acid Prescription)
Perceived effectiveness
for mixed connective tissue disease (6 evaluations)
Side effects
Total evaluations
6
Treatment name(s)

(Neurontin)
Perceived effectiveness
for pain (8 evaluations)
Side effects
drowsiness weight gain 1 more
Total evaluations
9
Tried for
pain (11)
Treatment name(s)

(Naproxen Prescription)
Perceived effectiveness
for mixed connective tissue disease (6 evaluations)
Side effects
abdominal pain gastric ulcer 2 more
Total evaluations
6
Treatment name(s)

(Flexeril)
Perceived effectiveness
for pain (10 evaluations)
Side effects
drowsiness constipation 7 more
Total evaluations
10
Treatment name(s)

(Ultram)
Perceived effectiveness
for pain (2 evaluations)
Side effects
brain fog drowsiness 1 more
Total evaluations
2
Tried for
pain (6)
Treatment name(s)

(Wellbutrin XL)
Perceived effectiveness
for depressed mood (1 evaluation)
Side effects
weight gain
Total evaluations
1
Tried for
depressed mood (4)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for depressed mood (1 evaluation)
Side effects
acid reflux dizziness and feeling faint 9 more
Total evaluations
3
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
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Who has mixed connective tissue disease on PatientsLikeMe?


Age
Age Proportion # of patients
<20 7
20s 52
30s 174
40s 322
50s 399
60s 205
70+ 38
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 66
20-29 years 83
30-39 years 136
40-49 years 114
50-59 years 44
60-69 years 11
70+ years 0

Distribution of sex

Sex
Sex Proportion # of patients
Male 49
Female 1156

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 579
Not Diagnosed 29

These charts show data from mixed connective tissue disease patients who have completed their condition history
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