• Effectiveness

  None (for pyroluria syndrome)
• Side effects

  None
• Adherence

  Usually
• Burden

  Somewhat hard to take

Dosage: 200 mcg Daily

Advice & Tips: didn't work for me

Cost: < $25 monthly

• Effectiveness

  Can't tell (for pyroluria syndrome)
• Side effects

  None
• Adherence

  Usually
• Burden

  A little hard to take

Dosage: 200 mcg Daily

Cost: < $25 monthly

• Effectiveness

  Major (for amyotrophic lateral sclerosis)
• Side effects

  Mild (diarrhea)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 5000 mg Daily

Advice & Tips: I have ALS with both upper and lower neurone damage yet my progression has been slow having survived 14 years from first symptoms and still have quality of life. The only side effect was occasional diahoria which I think was natures way of saying you have taken a bit too much. I would recommend people to take it as soon as possible after diagnosis. It needs to be natural vitamin-E. Look at Dr Carsten Hager and vitamin E on the internet to find out why I take it.

Cost: < $25 monthly

• Effectiveness

  Can't tell (for amyotrophic lateral sclerosis)
• Side effects

  None
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 5000 mg Daily

Advice & Tips: Build up to the full dose over 2-3 weeks. The only side effect I have had is occasional diahorea which seems to be the body's way of telling you you have taken too much. I would advise plwMND to take it as early as possible (two thirds dose mid am and remaining 1/3 mid p.m)

Cost: < $25 monthly

• Effectiveness

  Moderate (for Support immune health)
• Effectiveness

  Slight (for Support heart health)
• Side effects

  None
• Adherence

  Always
• Burden

  Not at all hard to take

Cost: < $25 monthly