Restless legs syndrome

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What is restless legs syndrome?

Restless legs syndrome (RLS) is a neurological disorder characterized by an unpleasant sensation in the legs and an urge to move them for relief; usually occurs during periods of inactivity, particularly at night. RLS sensations may also be felt in the arms or other parts of the body.

Common symptoms reported by people with restless legs syndrome

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
Last updated:

Treatments taken by people with restless legs syndrome

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Mirapex)
Type
Prescription Drug
How many have tried
67
Treatment name(s)

(Requip)
Type
Prescription Drug
How many have tried
66
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
47
Tried for
pain (25) restless legs syndrome (25)
2 more
Treatment name(s)

(Klonopin)
Type
Prescription Drug
How many have tried
29
Tried for
anxious mood (22) restless legs syndrome (8)
1 more
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
24
Tried for
pain (21) restless legs syndrome (3)
Treatment name(s)

(Norco)
Type
Prescription Drug
How many have tried
21
Tried for
pain (21)
Treatment name(s)

(Lexapro)
Type
Prescription Drug
How many have tried
19
Tried for
depressed mood (16) anxious mood (10)
3 more
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
17
Tried for
depressed mood (13) anxious mood (5)
2 more
Treatment name(s)

(Cannabidiol CBD oil)
Type
Other
How many have tried
16
Tried for
pain (14) anxious mood (8)
3 more
Treatment name(s)

(Lyrica)
Type
Prescription Drug
How many have tried
15
Tried for
pain (13) restless legs syndrome (4)

Data from patients with restless legs syndrome, who reported starting treatments within the last 5 years.
Last updated:

Compare treatments taken by people with restless legs syndrome

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Mirapex)
Perceived effectiveness
for restless legs syndrome (40 evaluations)
Side effects
nausea difficulty staying asleep 19 more
Total evaluations
42
Treatment name(s)

(Requip)
Perceived effectiveness
for restless legs syndrome (41 evaluations)
Side effects
nausea cramps in calf muscles 11 more
Total evaluations
52
Treatment name(s)

(Neurontin)
Perceived effectiveness
for pain (43 evaluations)
Side effects
excessive daytime sleepiness (somnolence) memory problems 20 more
Total evaluations
56
Tried for
pain (25) restless legs syndrome (25)
2 more
Treatment name(s)

(Klonopin)
Perceived effectiveness
for anxious mood (11 evaluations)
Side effects
headaches increased sleepiness 3 more
Total evaluations
17
Tried for
anxious mood (22) restless legs syndrome (8)
1 more
Treatment name(s)

(Ultram)
Perceived effectiveness
for pain (7 evaluations)
Side effects
nausea drowsiness 3 more
Total evaluations
8
Tried for
pain (21) restless legs syndrome (3)
Treatment name(s)

(Norco)
Perceived effectiveness
for pain (14 evaluations)
Side effects
drowsiness chronic constipation 2 more
Total evaluations
15
Tried for
pain (21)
Treatment name(s)

(Lexapro)
Perceived effectiveness
for depressed mood (11 evaluations)
Side effects
drowsiness cognitive confusion 13 more
Total evaluations
12
Tried for
depressed mood (16) anxious mood (10)
3 more
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for depressed mood (16 evaluations)
Side effects
abdominal pain bipolar depressive episodes 34 more
Total evaluations
23
Tried for
depressed mood (13) anxious mood (5)
2 more
Treatment name(s)

(Cannabidiol CBD oil)
Perceived effectiveness
for pain (9 evaluations)
Side effects
agitation paranoia
Total evaluations
9
Tried for
pain (14) anxious mood (8)
3 more
Treatment name(s)

(Lyrica)
Perceived effectiveness
for pain (14 evaluations)
Side effects
blurry vision fatigue 7 more
Total evaluations
14
Tried for
pain (13) restless legs syndrome (4)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with restless legs syndrome, who reported starting treatments within the last 5 years.
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Who has restless legs syndrome on PatientsLikeMe?


Age
Age Proportion # of patients
<20 7
20s 78
30s 325
40s 785
50s 1050
60s 895
70+ 339
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 328
20-29 years 283
30-39 years 420
40-49 years 405
50-59 years 194
60-69 years 46
70+ years 11

Distribution of sex

Sex
Sex Proportion # of patients
Male 559
Female 2929

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 1836
Not Diagnosed 270

These charts show data from restless legs syndrome (RLS) patients who have completed their condition history
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