What is Apomorphine?

Category: Prescription Drugs

Most popular types: Apokyn Apomorphine Injection

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Apomorphine is a dopamine agonist that is used for the treatment of hypomobility, "off" episodes with Parkinson's disease. It may also be used to treat erectile dysfunction. Apomorphine can induce vomiting so it is recommended that antiemetic therapy should start before initiation of treatment.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 24 21
Improve mobility 7 12
Stiffness/spasticity 7 5
Slow movement (bradykinesia) 2 1
Cold feet 1 0
Fatigue 1 0

Show all 10 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
2
Moderate
4
Mild
8
None
14

Commonly reported side effects and conditions associated with Apomorphine

Side effect Patients
Nausea 5
Jerky movements 2
Dizziness 1
Dizziness and feeling faint 1
Excessive yawning 1
Generalized weakness (asthenia) 1

Show all 17 reported side effects

Dosages

Based on patients currently taking Apomorphine

Dosage Patients
10mg/ml as needed 2
2 mL five times daily 1
3 mg five times daily 1
0.35ml as needed 1
0.3mg as needed 1
0.4 10mg/ml as needed 1
2mg as needed 1

Why patients stopped taking Apomorphine

Multiple reasons could be selected

Reason Patients
Other 5
Side effects too severe 4
Did not seem to work 2
Doctor's advice 1
Expense 1
See all 12 patients who've stopped taking Apomorphine

Duration

Currently taking Apomorphine

Duration Patients
1 - 6 months 2
1 - 2 years 1
2 - 5 years 5
10 years or more 1

Stopped taking Apomorphine

Duration Patients
Less than 1 month 4
1 - 6 months 5
6 months - 1 year 2
1 - 2 years 1
Adherence
Adherence Evaluations
Always 8
Usually 14
Sometimes 4
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 12
A little hard to take 10
Not at all hard to take 4
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 0
$50-99 1
$25-49 1
< $25 7
Not specified 17

What people switch to and from

Patients started taking Apomorphine after stopping:

Treatment Patients
Carbidopa-Entacapone-Levodopa (Stalevo) 1
Carbidopa-Levodopa (Sinemet) 1
Carbidopa-Levodopa CR (Sinemet CR) 1

Patients stopped taking Apomorphine and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 1
Carbidopa-Levodopa CR (Sinemet CR) 1
Entacapone (Comtan) 1
Last updated:

5 patient evaluations for Apomorphine

Mar 15, 2016 (Started Sep 10, 2014)

  • Effectiveness
    None (for Parkinson's disease)
  • Effectiveness
    None (for Improve mobility)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: I am not currently taking Apokyn as, due to the success of our informal trial using hypnotherapy, it has not been necessary. I am not sure how to record this on the site. Hypnotherapy is a private treatment in UK & costs £35 per session weekly
Cost: $200+ monthly

Oct 28, 2015 (Started Sep 10, 2014)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for Improve mobility)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: Until September 13th my condition was deteriorating re freezing so that for some time I needed 4-5 injections a day & was recommended to start using the pump. A hypnotherapy programme to address freezing was initiated & from a few days in I have not had an injection ie from 20th September.

Aug 21, 2015 (Started Sep 10, 2014)

  • Effectiveness
    None (for Parkinson's disease)
  • Effectiveness
    Major (for Improve mobility)
  • Side effects
    Mild (injection site bruising)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed

May 31, 2015 (Started Sep 10, 2014)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Major (for Improve mobility)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: As needed

May 5, 2015 (Started Sep 10, 2014)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Major (for Improve mobility)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed

Apr 13, 2015 (Started Sep 10, 2014)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for Improve mobility)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: As needed

Mar 19, 2015 (Started Sep 10, 2014)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Major (for Improve mobility)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: For 9 consecutive days I only need 4 injections in total. After that the freezing & internal tremor returned, though not so frequently with resulting increase of injections.

Mar 4, 2015 (Started Sep 10, 2014)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for Improve mobility)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: I have only had 4 injections in the last 9 days. I'm not sure why but my overall condition seems to have benefited from Apokyn - not just the freezing.

Jan 19, 2015 (Started Sep 10, 2014)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for Improve mobility)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: I think that I have needed to use the injections less than I planned for almost like an umbrella keeps away the rain. It is an effective prop.

  • 1 helpful mark

Dec 12, 2013 (Started Dec 06, 2013)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for Improve mobility)
  • Side effects
    Mild (nausea)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 10 mg Daily
Advice & Tips: I couldn't walk in the mornings for at least 45 minutes. I had to crawl on my hands and knees to go to the bathroom. Apokyn kicks in in no more than 10 minutes.
Cost: $50-99 monthly

  • 0 helpful marks

Feb 25, 2010 (Started Feb 25, 2010)

  • Effectiveness
    Major (for to see if it work for me now waiting for doctor to see whats what)
  • Side effects
    Mild (motion sickness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Side effects: motion sickness

  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Apomorphine