What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 1,538 890
Epilepsy 1,104 529
Bipolar II disorder 773 467
Bipolar I disorder 455 285
Depressed mood 161 107
Major depressive disorder 158 124

Show all 205 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 270
Moderate 416
Mild 602
None 971

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Weight gain 77
Dizziness 70
Headaches 69
Rashes (redness, swelling) 52
Nausea 50
Fatigue 47

Show all 517 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 148
100 mg daily 92
150 mg daily 57
25 mg daily 49
300 mg daily 45
200 mg twice daily 43
100 mg twice daily 39
50 mg daily 32
400 mg daily 32
150 mg twice daily 20

See all 64 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 462
Did not seem to work 407
Doctor's advice 272
Other 199
Expense 69
Personal research 54
Course of treatment ended 42
Change in health plan coverage 35
See all 1036 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 1
1 - 6 months 35
6 months - 1 year 64
1 - 2 years 99
2 - 5 years 201
5 - 10 years 189
10 years or more 112

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 238
1 - 6 months 241
6 months - 1 year 154
1 - 2 years 139
2 - 5 years 171
5 - 10 years 93
10 years or more 17
Adherence
Adherence Evaluations
Always 1848
Usually 284
Sometimes 50
Never taken as prescribed 77
Burden
Burden Evaluations
Very hard to take 96
Somewhat hard to take 205
A little hard to take 370
Not at all hard to take 1588
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 50
$50-99 65
$25-49 120
< $25 1049
Not specified 933

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 100
Divalproex sodium (Depakote) 48
Quetiapine (Seroquel) 48
Aripiprazole (Abilify) 43
Bupropion (Wellbutrin XL) 24

Show all 54 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 37
Aripiprazole (Abilify) 26
Quetiapine (Seroquel) 21
Divalproex sodium (Depakote) 14
Lurasidone (Latuda) 14

Show all 60 treatments patients report switching to

Last updated:

140 patient evaluations for Lamotrigine

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks

Jan 18, 2017 (Started Jul 01, 2009)

  • Effectiveness
    Major (for bipolar II disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Don't go off without talking to doctor. I came out of the fog after starting this medication.

  • 0 helpful marks

Aug 10, 2016 (Started Oct 25, 2012)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Effectiveness
    Can't tell (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 140 patient evaluations for Lamotrigine