What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 1,067 555
Epilepsy 1,051 475
Bipolar II Disorder 558 314
Bipolar I Disorder 345 206
Depressed mood 140 91
Borderline Personality Disorder 123 70

Show all 206 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 193
Moderate 336
Mild 458
None 674

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 64
Headaches 59
Weight gain 50
Insomnia 42
Nausea 42
Problems concentrating 41

Show all 471 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 77
100 mg daily 50
25 mg daily 36
150 mg daily 27
300 mg daily 26
200 mg twice daily 22
400 mg daily 20
50 mg daily 18
100 mg twice daily 18
150 mg twice daily 12

See all 43 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 359
Did not seem to work 343
Doctor's advice 225
Other 165
Expense 57
Personal research 48
Course of treatment ended 34
Change in health plan coverage 28
See all 841 patients who’ve stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 1
1 - 6 months 30
6 months - 1 year 43
1 - 2 years 66
2 - 5 years 102
5 - 10 years 103
10 years or more 56

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 172
1 - 6 months 212
6 months - 1 year 135
1 - 2 years 117
2 - 5 years 134
5 - 10 years 73
10 years or more 13
Adherence
Adherence Evaluations
Always 1352
Usually 225
Sometimes 35
Never taken as prescribed 49
Burden
Burden Evaluations
Very hard to take 70
Somewhat hard to take 156
A little hard to take 288
Not at all hard to take 1147
Cost per month
Cost per month Evaluations
$200+ 38
$100-199 44
$50-99 57
$25-49 104
< $25 785
Not specified 633

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 40
Aripiprazole (Abilify) 22
Divalproex sodium (Depakote) 21
Quetiapine (Seroquel) 19
Carbamazepine (Tegretol) 13

Show all 47 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 12
Quetiapine (Seroquel) 12
Aripiprazole (Abilify) 11
Oxcarbazepine (Trileptal) 9
Divalproex sodium (Depakote) 8

Show all 39 treatments patients report switching to

Last updated:

137 patient evaluations for Lamotrigine

1,245 members have decided to share their profiles only with other members of PatientsLikeMe.

zoomer
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zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Low
61 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Lamotrigine history

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
rain or shine
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rain or shine
Gender: F
Data Quality: 1 star
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: None
53 F
Function: High
Distress: Low
I am: n
I have:
Bipolar I

See rain or shine's full Lamotrigine history

Nov 15, 2015 (Started Dec 01, 2009)

  • Effectiveness
    Slight (for Bipolar rapid cycling)
  • Effectiveness
    Slight (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 125 mg Daily
Cost: $200+ monthly

Mar 25, 2011 (Started Dec 01, 2009)

  • Effectiveness
    Moderate (for Bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 125 mg Daily
Cost: < $25 monthly

Jul 25, 2010 (Started Dec 01, 2009)

  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: This medicine really has helped my mood disorder. I stay fairly even most of the time. Start this medication at a VERY low dose and titrate up slowly maybe raising the dosage only every two weeks. This helped me to adjust easily and my current dosage is perfect so far but as we know everything is subject to change any day. lol. I feel almost normal again.
Cost: < $25 monthly

  • 1 helpful mark
God's Worshipper
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God's Worshipper
Gender: M
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Low
59 M
Function: High
Distress: Low
I am: n
I have:
Schizoaffective Disorder

See God's Worshipper's full Lamotrigine history

Oct 27, 2015 (Started Dec 15, 2012)

  • Effectiveness
    None (for Schizoaffective Disorder)
  • Effectiveness
    None (for Mood swings)
  • Effectiveness
    None (for Borderline Personality Disorder)
  • Effectiveness
    None (for Bipolar rapid cycling)
  • Effectiveness
    None (for Bipolar II Disorder)
  • Effectiveness
    None (for Bipolar I Disorder)
  • Effectiveness
    None (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

Feb 24, 2015 (Started Dec 15, 2012)

  • Effectiveness
    None (for Borderline Personality Disorder)
  • Effectiveness
    None (for Bipolar II Disorder)
  • Effectiveness
    None (for Bipolar Disorder)
  • Effectiveness
    None (for Schizoaffective Disorder)
  • Effectiveness
    None (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Apr 29, 2013 (Started Dec 15, 2012)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Borderline Personality Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 137 patient evaluations for Lamotrigine