What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 1,095 579
Epilepsy 1,058 482
Bipolar II Disorder 567 324
Bipolar I Disorder 353 210
Depressed mood 140 91
Borderline Personality Disorder 125 69

Show all 207 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 200
Moderate 342
Mild 469
None 695

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 65
Headaches 59
Weight gain 52
Nausea 43
Insomnia 42
Problems concentrating 41

Show all 470 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 83
100 mg daily 54
25 mg daily 37
300 mg daily 32
150 mg daily 31
400 mg daily 24
100 mg twice daily 23
200 mg twice daily 23
50 mg daily 18
150 mg twice daily 16

See all 48 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 361
Did not seem to work 348
Doctor's advice 232
Other 164
Expense 58
Personal research 48
Course of treatment ended 34
Change in health plan coverage 30
See all 850 patients who’ve stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 9
1 - 6 months 17
6 months - 1 year 50
1 - 2 years 76
2 - 5 years 125
5 - 10 years 111
10 years or more 56

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 173
1 - 6 months 217
6 months - 1 year 136
1 - 2 years 119
2 - 5 years 135
5 - 10 years 73
10 years or more 13
Adherence
Adherence Evaluations
Always 1391
Usually 228
Sometimes 37
Never taken as prescribed 50
Burden
Burden Evaluations
Very hard to take 75
Somewhat hard to take 163
A little hard to take 292
Not at all hard to take 1176
Cost per month
Cost per month Evaluations
$200+ 39
$100-199 45
$50-99 59
$25-49 105
< $25 797
Not specified 661

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 44
Divalproex sodium (Depakote) 25
Quetiapine (Seroquel) 24
Aripiprazole (Abilify) 23
Carbamazepine (Tegretol) 14

Show all 48 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 15
Quetiapine (Seroquel) 12
Aripiprazole (Abilify) 10
Oxcarbazepine (Trileptal) 9
Divalproex sodium (Depakote) 8

Show all 44 treatments patients report switching to

Last updated:

135 patient evaluations for Lamotrigine

1,285 members have decided to share their profiles only with other members of PatientsLikeMe.

zoomer
60535 thumb
zoomer
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Low
61 F
Function: High
Distress: Low
I am: g
I have:
Bipolar I

See zoomer's full Lamotrigine history

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
rain or shine
33055 thumb
rain or shine
Gender: F
Data Quality: 1 star
Depression: 1
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: None
54 F
Function: High
Distress: Low
I am: n
I have:
Bipolar I

See rain or shine's full Lamotrigine history

Nov 15, 2015 (Started Dec 01, 2009)

  • Effectiveness
    Slight (for Bipolar rapid cycling)
  • Effectiveness
    Slight (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 125 mg Daily
Cost: $200+ monthly

Mar 25, 2011 (Started Dec 01, 2009)

  • Effectiveness
    Moderate (for Bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 125 mg Daily
Cost: < $25 monthly

Jul 25, 2010 (Started Dec 01, 2009)

  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: This medicine really has helped my mood disorder. I stay fairly even most of the time. Start this medication at a VERY low dose and titrate up slowly maybe raising the dosage only every two weeks. This helped me to adjust easily and my current dosage is perfect so far but as we know everything is subject to change any day. lol. I feel almost normal again.
Cost: < $25 monthly

  • 1 helpful mark
UfieDufie
31313 thumb
UfieDufie
Sex: F
Data Quality: 2 stars
Relapse: Moderate
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: mild
Swallowing: moderate
Upper limb: mild
Walking: moderate
I am: b
I have:
MS

See UfieDufie's full Lamotrigine history

Aug 4, 2015 (Started Mar 15, 2015)

  • Effectiveness
    Slight (for Bipolar Disorder)
  • Side effects
    Moderate (Rashes (redness, swelling))
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 300 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 135 patient evaluations for Lamotrigine