What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 1,521 874
Epilepsy 1,100 526
Bipolar II disorder 767 463
Bipolar I disorder 452 280
Depressed mood 160 106
Major depressive disorder 158 121

Show all 205 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
268
Moderate
414
Mild
594
None
952

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Weight gain 72
Dizziness 69
Headaches 68
Rashes (redness, swelling) 53
Nausea 49
Fatigue 48

Show all 524 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 146
100 mg daily 103
150 mg daily 60
25 mg daily 57
200 mg twice daily 49
300 mg daily 45
400 mg daily 36
50 mg daily 35
100 mg twice daily 35
150 mg twice daily 20

See all 66 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 459
Did not seem to work 403
Doctor's advice 268
Other 199
Expense 68
Personal research 54
Course of treatment ended 42
Change in health plan coverage 35
See all 1023 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 4
1 - 6 months 48
6 months - 1 year 73
1 - 2 years 97
2 - 5 years 208
5 - 10 years 186
10 years or more 129

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 235
1 - 6 months 237
6 months - 1 year 153
1 - 2 years 137
2 - 5 years 170
5 - 10 years 92
10 years or more 16
Adherence
Adherence Evaluations
Always 1821
Usually 283
Sometimes 48
Never taken as prescribed 76
Burden
Burden Evaluations
Very hard to take 95
Somewhat hard to take 201
A little hard to take 368
Not at all hard to take 1564
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 50
$50-99 65
$25-49 119
< $25 1035
Not specified 917

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 96
Quetiapine (Seroquel) 48
Divalproex sodium (Depakote) 47
Aripiprazole (Abilify) 43
Bupropion (Wellbutrin XL) 23

Show all 53 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 38
Aripiprazole (Abilify) 24
Quetiapine (Seroquel) 22
Divalproex sodium (Depakote) 13
Lurasidone (Latuda) 13

Show all 60 treatments patients report switching to

Last updated:

140 patient evaluations for Lamotrigine

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks

Jan 18, 2017 (Started Jul 01, 2009)

  • Effectiveness
    Major (for bipolar II disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Don't go off without talking to doctor. I came out of the fog after starting this medication.

  • 0 helpful marks

Aug 10, 2016 (Started Oct 25, 2012)

  • Effectiveness
    Can't tell (for major depressive disorder)
  • Effectiveness
    Can't tell (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 140 patient evaluations for Lamotrigine