What is Rituximab?

Category: Prescription Drugs

Most popular types: Rituxan Mabthera

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See also: DRC protocol FCMR protocol ILD Phase II/III Rituximab Versus Cyclophosphamide RECITAL Study R-CVP protocol RT protocol

Rituximab is a medication in a class of medications called monoclonal antibodies and given by infusion. It is used in the treatment of non-Hodgkins lymphoma and also in the treatment of rheumatoid arthritis.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple Sclerosis 90 60
Rheumatoid Arthritis (RA) 67 34
Neuromyelitis Optica 54 31
Systemic Lupus Erythematosus 17 7
CLL (Chronic Lymphocytic Leukemia) 15 6
Follicular Lymphoma 11 5

Show all 85 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 28
Moderate 31
Mild 60
None 62

Commonly reported side effects and conditions associated with Rituximab

Side effect Patients
Fatigue 20
Nausea 17
Allergic reaction 7
Headaches 7
Flu like symptoms 6
Hair loss 4

Show all 115 reported side effects

Dosages

Based on patients currently taking Rituximab

Dosage Patients
10 mg every 6 months 4
1,000 mg every 6 months 3
10 mg monthly 2
1,000 mg yearly 2
1,000 mg every 3 months 2
2 Chemo cycles yearly 1
1 mcg every 8 weeks 1
2 g every 3 months 1
10 mg every 3 months 1
10 mg every 12 weeks 1

See all 30 dosages

Why patients stopped taking Rituximab

Multiple reasons could be selected

Reason Patients
Course of treatment ended 53
Did not seem to work 32
Doctor's advice 27
Side effects too severe 23
Other 15
Change in health plan coverage 4
Expense 4
Personal research 2
See all 133 patients who’ve stopped taking Rituximab

Duration

Currently taking Rituximab

Duration Patients
1 - 6 months 5
6 months - 1 year 10
1 - 2 years 8
2 - 5 years 14
5 - 10 years 6
10 years or more 1

Stopped taking Rituximab

Duration Patients
Less than 1 month 53
1 - 6 months 29
6 months - 1 year 15
1 - 2 years 14
2 - 5 years 20
5 - 10 years 2
Adherence
Adherence Evaluations
Always 157
Usually 8
Sometimes 4
Never taken as prescribed 12
Burden
Burden Evaluations
Very hard to take 17
Somewhat hard to take 54
A little hard to take 60
Not at all hard to take 50
Cost per month
Cost per month Evaluations
$200+ 31
$100-199 10
$50-99 5
$25-49 2
< $25 52
Not specified 81

What people switch to and from

Patients started taking Rituximab after stopping:

Treatment Patients
Natalizumab (Tysabri) 9
Dimethyl fumarate (Tecfidera) 6
Abatacept (Orencia) 4
Fingolimod (Gilenya) 4
Intravenous Immunoglobulin (IVIG) (Gammaglobulin (IVIg)) 4

Show all 32 treatments patients report switching from

Patients stopped taking Rituximab and switched to:

Treatment Patients
Ibrutinib (Imbruvica) 3
Tocilizumab (Actemra) 3
Methotrexate (Apo-Methotrexate) 2
Natalizumab (Tysabri) 2
Alemtuzumab (Lemtrada) 1

Show all 12 treatments patients report switching to

Last updated:

17 patient evaluations for Rituximab

143 members have decided to share their profiles only with other members of PatientsLikeMe.

gummitarzan
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gummitarzan
Data Quality: 3 stars
  • Gender: M
  • Age: 69
Condition: Rheumatoid Arthritis (RA) 5 additional condition(s)
Quality of life:
  • Mental: None
  • Physical: Mild
I am: g
I have:
Rheumatoid Arthritis (RA)

See gummitarzan's full Rituximab history

Sep 24, 2016 (Started Sep 11, 2014)

  • Effectiveness
    Slight (for Rheumatoid Arthritis (RA))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: I had 2 infusions, 14 days apart. And that was it. The effect was not worth the price according to my rheumatologist (I paid nothing myself)
Cost: < $25 monthly

Jul 1, 2014 (Started Sep 11, 2014)

  • Effectiveness
    Slight (for Rheumatoid Arthritis (RA))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Cost: < $25 monthly

  • 0 helpful marks
tlheyne
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tlheyne
Data Quality: 1 star
  • Gender: F
  • Age: 62
Condition: Transverse Myelitis 3 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: g
I have:
Transverse Myelitis

See tlheyne's full Rituximab history

Mar 24, 2016 (Started Feb 25, 2016)

  • Effectiveness
    Can’t tell (for Transverse Myelitis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 10 mg Every 6 months
Advice & Tips: I haven't had any side effects. I cannot tell if there are any unexpected benefits. It takes a full day for me to drive to where my infusion takes place, then drive home. The hospital is 1 1/2 hours one way. The infusion itself takes 6 hours, a week apart. Then the same drive time back home.
Cost: < $25 monthly

  • 0 helpful marks
bebp
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bebp
Data Quality: 1 star
  • Gender: F
  • Age: 57
Condition: Rheumatoid Arthritis (RA) 4 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: g
I have:
Rheumatoid Arthritis (RA)

See bebp's full Rituximab history

Sep 15, 2014 (Started Jul 15, 2012)

  • Effectiveness
    Slight (for Rheumatoid Arthritis (RA))
  • Side effects
    Mild (Sinus headaches)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 10 mg Every 3 months
Advice & Tips: This was an infusion. Go prepared to sit back and relax. Take the Benedryl offered to you and go to sleep for a while. Depending on the dose, you may be there for five hours (or as little as two). Bring a book. No work. No annoying phone calls. This was a perfect excuse to rest. You will havwe to go into the doctor's office and miss a day of work. Immediately after an infusion I would be hungry and tired. So I would go home and take a nap after lunch. Because of small veins and constant dehydration, it would take five to five and a half hours for me to get my dosage. I went once every six months initially, then once every four months. If after three doses you were not getting any relief, talk to your doctor. She may wish to change the number of times you were getting treated.

  • 0 helpful marks
Last updated:
Showing 3 of 17 patient evaluations for Rituximab