What is Amantadine?

Category: Prescription Drugs

Most popular types: Symmetrel PK Merz Mantidan Show all

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Amantadine is used to treat Parkinson's Disease and "parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs. It is also an antiviral medication that may be used to treat and prevent certain strains of influenza A.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 919 556
Fatigue 578 301
Excessive daytime sleepiness (somnolence) 81 56
Jerky movements (dyskinesia) 43 25
Stiffness/Spasticity 36 10
Tremor(s) 36 35

Show all 116 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 90
Moderate 122
Mild 183
None 541

Commonly reported side effects and conditions associated with Amantadine

Side effect Patients
Dry mouth 22
Fatigue 17
Constipation 16
Blotchy skin on my legs 11
Blurry vision 11
General ill feeling 10

Show all 193 reported side effects

Dosages

Based on patients currently taking Amantadine

Dosage Patients
100 mg twice daily 58
100 mg daily 50
200 mg daily 47
100 mg three times daily 30
300 mg daily 18
200 mg twice daily 7
400 mg daily 7
100 mg four times daily 4
300 mg three times daily 3
4 x 50 mg/5 mL daily 2

See all 19 dosages

Why patients stopped taking Amantadine

Multiple reasons could be selected

Reason Patients
Did not seem to work 276
Side effects too severe 171
Doctor's advice 126
Other 66
Course of treatment ended 20
Personal research 16
Expense 14
Change in health plan coverage 3
See all 552 patients who've stopped taking Amantadine

Duration

Currently taking Amantadine

Duration Patients
Less than 1 month 2
1 - 6 months 11
6 months - 1 year 12
1 - 2 years 28
2 - 5 years 57
5 - 10 years 86
10 years or more 44

Stopped taking Amantadine

Duration Patients
Less than 1 month 88
1 - 6 months 172
6 months - 1 year 89
1 - 2 years 65
2 - 5 years 91
5 - 10 years 37
10 years or more 11
Adherence
Adherence Evaluations
Always 707
Usually 132
Sometimes 33
Never taken as prescribed 64
Burden
Burden Evaluations
Very hard to take 28
Somewhat hard to take 50
A little hard to take 129
Not at all hard to take 729
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 23
$50-99 22
$25-49 64
< $25 469
Not specified 348

What people switch to and from

Patients started taking Amantadine after stopping:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 6
Pramipexole (Mirapex) 6
Rasagiline (Azilect) 4
Ropinirole (Requip) 3
Amphetamine-Dextroamphetamine (Adderall) 2

Show all 16 treatments patients report switching from

Patients stopped taking Amantadine and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 17
Modafinil (Provigil) 7
Pramipexole (Mirapex) 5
Ropinirole (Requip) 4
Rasagiline (Azilect) 3

Show all 20 treatments patients report switching to

Last updated:

110 patient evaluations for Amantadine

Dec 15, 2016 (Started Jun 24, 2008)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Effectiveness
    Moderate (for Jerky movements (dyskinesia))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly
Side effects: Dry mouth

Oct 17, 2009 (Started Jun 24, 2008)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Once a week, I can walk for about half an hour before taking my medication. This began shortly after I started Mirapex. I stopped Amantadine and Azilect prior to hernia surgery. After surgery, I resumed the Azilect but not the Amantadine, and could not do my weekly walk without medication. Adding the Amantadine fixed that.
Cost: < $25 monthly
Side effects: Dry mouth

Mar 29, 2009 (Started Jun 24, 2008)

  • Effectiveness
    None (for Don't know)
  • Side effects
    Mild (Dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly
Side effects: Dry mouth

  • 0 helpful marks

Oct 22, 2016 (Started Mar 20, 2002)

  • Effectiveness
    Can’t tell (for Jerky movements (dyskinesia))
  • Effectiveness
    Can’t tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 100 mg Four times daily
Advice & Tips: I don't have any advice, a tip might be to listen to your body
Cost: $25-49 monthly

Jan 29, 2016 (Started Mar 20, 2002)

  • Effectiveness
    Can’t tell (for Jerky movements (dyskinesia))
  • Effectiveness
    Can’t tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Four times daily
Advice & Tips: I have been taking Amantadine so long, I don't know what it does anymore or if it helps with Dyskinesia or not.
Cost: $50-99 monthly

Sep 19, 2008 (Started Mar 20, 2002)

  • Effectiveness
    Can’t tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily

  • 0 helpful marks

Oct 20, 2016 (Started Jul 01, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Cost: < $25 monthly

Jun 20, 2015 (Started Jul 01, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: I was curling my toes tightly causing pain and discomfort. This drug has halted that problem.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 110 patient evaluations for Amantadine