What is Amantadine?

Category: Prescription Drugs

Most popular types: Symmetrel PK Merz Mantidan Show all

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See also: Amantadine-amitriptyline-baclofen-clonidine-lidocaine-nifedipine-prilocaine

Amantadine is used to treat Parkinson's Disease and "parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs. It is also an antiviral medication that may be used to treat and prevent certain strains of influenza A.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 939 584
Fatigue 583 310
Excessive daytime sleepiness (somnolence) 84 59
Jerky movements 44 28
Stiffness/spasticity 37 11
Tremor(s) 36 35

Show all 110 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
92
Moderate
128
Mild
189
None
567

Commonly reported side effects and conditions associated with Amantadine

Side effect Patients
Dry mouth 22
Fatigue 17
Constipation 16
Blurry vision 12
Blotchy skin on my legs 11
Nausea 11

Show all 196 reported side effects

Dosages

Based on patients currently taking Amantadine

Dosage Patients
200 mg daily 64
100 mg daily 59
100 mg twice daily 59
100 mg three times daily 27
300 mg daily 18
400 mg daily 10
200 mg twice daily 8
4 x 50 mg/5 mL daily 2
100 mg four times daily 2
300 mg three times daily 2

See all 27 dosages

Why patients stopped taking Amantadine

Multiple reasons could be selected

Reason Patients
Did not seem to work 277
Side effects too severe 178
Doctor's advice 130
Other 66
Course of treatment ended 20
Personal research 16
Expense 14
Change in health plan coverage 3
See all 561 patients who've stopped taking Amantadine

Duration

Currently taking Amantadine

Duration Patients
1 - 6 months 9
6 months - 1 year 16
1 - 2 years 24
2 - 5 years 65
5 - 10 years 103
10 years or more 57

Stopped taking Amantadine

Duration Patients
Less than 1 month 100
1 - 6 months 168
6 months - 1 year 88
1 - 2 years 65
2 - 5 years 93
5 - 10 years 38
10 years or more 11
Adherence
Adherence Evaluations
Always 745
Usually 132
Sometimes 34
Never taken as prescribed 65
Burden
Burden Evaluations
Very hard to take 29
Somewhat hard to take 48
A little hard to take 134
Not at all hard to take 765
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 28
$50-99 24
$25-49 65
< $25 484
Not specified 365

What people switch to and from

Patients started taking Amantadine after stopping:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 7
Pramipexole (Mirapex) 6
Rasagiline (Azilect) 4
Ropinirole (Requip) 4
Amphetamine-Dextroamphetamine (Adderall) 2

Show all 17 treatments patients report switching from

Patients stopped taking Amantadine and switched to:

Treatment Patients
Carbidopa-Levodopa (Sinemet) 16
Modafinil (Provigil) 7
Pramipexole (Mirapex) 6
Rasagiline (Azilect) 4
Ropinirole (Requip) 4

Show all 20 treatments patients report switching to

Last updated:

111 patient evaluations for Amantadine

Dec 30, 2016 (Started Jan 19, 2012)

  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (nausea, muscle and joint pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Now that I have found the right cocktail I've been able to return to work full time. after being on disability for almost three years . so far it's been two months since I went back and I'm going strong . Don't get me wrong there are days when I'm exhausted from the nine hour day but it's a good kind of exhausted .
Cost: $100-199 monthly

Apr 16, 2014 (Started Jan 19, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (nausea, muscle and joint pain)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Cost: $100-199 monthly

Mar 11, 2012 (Started Jan 19, 2012)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    Mild (nausea, muscle and joint pain)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Jan 8, 2012 (Started Jan 19, 2012)

  • Effectiveness
    Major (for tremor in right wrist and hand during walking arm swing)
  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: It took me several trips to the Neurologist before we found the right drug cocktail. Now that I have found the right cocktail I've been able to return to work full time. after being on disability for almost three years . so far it's been two months since I went back and I'm going strong .  Don't get me wrong there are days when I'm exhausted from the nine hour day but it's a good kind of exhausted .  
Cost: $25-49 monthly

  • 0 helpful marks

Dec 15, 2016 (Started Jun 24, 2008)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Effectiveness
    Moderate (for jerky movements)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly
Side effects: dry mouth

Oct 17, 2009 (Started Jun 24, 2008)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Once a week, I can walk for about half an hour before taking my medication. This began shortly after I started Mirapex. I stopped Amantadine and Azilect prior to hernia surgery. After surgery, I resumed the Azilect but not the Amantadine, and could not do my weekly walk without medication. Adding the Amantadine fixed that.
Cost: < $25 monthly
Side effects: dry mouth

Mar 29, 2009 (Started Jun 24, 2008)

  • Effectiveness
    None (for Don't know)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly
Side effects: dry mouth

  • 0 helpful marks

Oct 22, 2016 (Started Mar 20, 2002)

  • Effectiveness
    Can't tell (for jerky movements)
  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 100 mg Four times daily
Advice & Tips: I don't have any advice, a tip might be to listen to your body
Cost: $25-49 monthly

Jan 29, 2016 (Started Mar 20, 2002)

  • Effectiveness
    Can't tell (for jerky movements)
  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Four times daily
Advice & Tips: I have been taking Amantadine so long, I don't know what it does anymore or if it helps with Dyskinesia or not.
Cost: $50-99 monthly

Sep 19, 2008 (Started Mar 20, 2002)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 111 patient evaluations for Amantadine