What is Memantine?

Category: Prescription Drugs

Most popular types: Namenda Namenda XR Ebixa Show all

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Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system. It is also being tested for use as a cognitive enhancer in a variety of other conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Cognitive impairment 34 15
Memory problems 23 13
Amyotrophic lateral sclerosis 22 5
Brain fog 12 6
Migraine headaches 9 4
Fibromyalgia 7 5

Show all 51 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
3
Moderate
7
Mild
10
None
43

Commonly reported side effects and conditions associated with Memantine

Side effect Patients
Ataxia (lack of coordination) 1
Brain fog 1
Constipation 1
Difficulty urinating (dysuria) 1
Dizziness 1
Euphoria 1

Show all 15 reported side effects

Dosages

Based on patients currently taking Memantine

Dosage Patients
10 mg twice daily 5
20 mg daily 5
28 mg daily 5
5 mg twice daily 4
10 mg daily 3
2 mg daily 1
5 mg daily 1
15 mg daily 1
20 mg twice daily 1
50 mg daily 1

Why patients stopped taking Memantine

Multiple reasons could be selected

Reason Patients
Did not seem to work 18
Doctor's advice 10
Side effects too severe 9
Expense 5
Other 3
Change in health plan coverage 2
Personal research 1
See all 36 patients who've stopped taking Memantine

Duration

Currently taking Memantine

Duration Patients
1 - 6 months 1
6 months - 1 year 3
1 - 2 years 5
2 - 5 years 9
5 - 10 years 4
10 years or more 5

Stopped taking Memantine

Duration Patients
Less than 1 month 9
1 - 6 months 7
6 months - 1 year 4
1 - 2 years 7
2 - 5 years 6
5 - 10 years 2
10 years or more 1
Adherence
Adherence Evaluations
Always 54
Usually 6
Sometimes 1
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 2
Somewhat hard to take 4
A little hard to take 10
Not at all hard to take 47
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 4
$50-99 12
$25-49 21
< $25 4
Not specified 21

What people switch to and from

Patients started taking Memantine after stopping:

Treatment Patients
Pregabalin (Lyrica) 2
Duloxetine (Cymbalta) 1
Levetiracetam (Keppra) 1
Memantine (Namenda) 1
Minocycline (Minocin) 1

Patients stopped taking Memantine and switched to:

Treatment Patients
Candesartan (Atacand) 1
Memantine (Namenda) 1
Last updated:

7 patient evaluations for Memantine

May 1, 2013 (Started Jan 15, 2013)

  • Effectiveness
    None (for migraine)
  • Side effects
    Severe (difficulty urinating (dysuria), extreme sedation, ataxia (lack of coordination))
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 20 mg Daily
Advice & Tips: I had such a bad experience, but I think I am an outlier, so I don't know whether or not to recommend this med. It really sucked for me.
Cost: $25-49 monthly

Feb 16, 2013 (Started Jan 15, 2013)

  • Effectiveness
    Can't tell (for migraine)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Dec 12, 2010 (Started Nov 23, 2010)

  • Effectiveness
    Moderate (for trying to get scrip - delay progression)
  • Effectiveness
    Moderate (for slow deterioration)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: increased mental alertness, less fatigue than normal, slight decline in fvc [2%]. initial effects similar to too much caffeine but only lasts 48hrs. currently on 10mg in am, 20mg in pm with no effect on sleeping on cpap - actually, sleeping better. dietary change around the same time to increase protein intake via drink supplements and eating more. much less fatigue but still in a chair most of the time. can still just get up and walk flat and level with a stick a little way - surprised because last week i thought it was all over for walking. fascics still there but not so noticeable.
Cost: $100-199 monthly

Nov 24, 2010 (Started Nov 23, 2010)

  • Effectiveness
    Major (for trying to get scrip - delay progression)
  • Effectiveness
    Can't tell (for slow deterioration)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: non pbs script is $103 per 28 tabs of 20mg. will take 10mg for 1 week and 20mg thereafter. local gp has offered to document condition changes for the record. will do bloods early dec 2010 as a baseline. this is the start evaluation, and will continue regularly - each week at least.
Cost: $100-199 monthly

  • 0 helpful marks

Dec 11, 2010 (Started May 06, 2009)

  • Effectiveness
    Slight (for amyotrophic lateral sclerosis)
  • Side effects
    Mild
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 7 patient evaluations for Memantine