What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,116 1,214
Depressed mood 1,558 762
Persistent depressive disorder (dysthymia) 372 312
Mild depression 149 62
Anxious mood 121 66
Bipolar disorder 106 92

Show all 214 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 254
Moderate 367
Mild 588
None 1,061

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 102
Anxious mood 65
Weight gain 54
Insomnia 49
Headaches 47
Constipation 42

Show all 433 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 185
150 mg daily 150
100 mg daily 96
75 mg daily 60
300 mg/24 hours daily 58
450 mg daily 49
150 mg twice daily 40
100 mg twice daily 37
200 mg daily 25
150 mg/24 hours daily 19

See all 80 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 613
Side effects too severe 519
Doctor's advice 399
Other 265
Course of treatment ended 85
Expense 80
Personal research 71
Change in health plan coverage 40
See all 1504 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 84
6 months - 1 year 75
1 - 2 years 140
2 - 5 years 230
5 - 10 years 199
10 years or more 164

Stopped taking Bupropion

Duration Patients
Less than 1 month 312
1 - 6 months 346
6 months - 1 year 240
1 - 2 years 214
2 - 5 years 260
5 - 10 years 116
10 years or more 56
Adherence
Adherence Evaluations
Always 1772
Usually 345
Sometimes 50
Never taken as prescribed 103
Burden
Burden Evaluations
Very hard to take 76
Somewhat hard to take 142
A little hard to take 331
Not at all hard to take 1721
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 84
$25-49 168
< $25 1099
Not specified 881

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 86
Fluoxetine (Prozac) 78
Venlafaxine (Effexor XR) 61
Citalopram (Celexa) 44
Duloxetine (Cymbalta) 44

Show all 53 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 44
Sertraline (Zoloft) 42
Venlafaxine (Effexor XR) 30
Citalopram (Celexa) 27
Escitalopram (Lexapro) 24

Show all 44 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion