What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

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Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
epilepsy 563 264
bipolar disorder 332 194
Migraine headaches 108 56
bipolar I disorder 45 32
Bipolar manic episodes 45 34
bipolar II disorder 41 33

Show all 131 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 167
Moderate 192
Mild 177
None 161

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 134
Hair loss 43
Fatigue 37
Drowsiness 25
Tremor in hands 22
Nausea 19

Show all 266 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
1,000 mg daily 26
500 mg twice daily 24
500 mg daily 20
250 mg daily 18
1,500 mg daily 16
250 mg twice daily 12
2,000 mg daily 9
750 mg daily 8
500 mg three times daily 7
1,000 mg twice daily 6

See all 30 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 314
Did not seem to work 224
Doctor's advice 155
Other 101
Personal research 35
Expense 28
Course of treatment ended 22
Change in health plan coverage 8
See all 577 patients who've stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
Less than 1 month 4
1 - 6 months 14
6 months - 1 year 13
1 - 2 years 27
2 - 5 years 35
5 - 10 years 43
10 years or more 45

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 102
1 - 6 months 134
6 months - 1 year 69
1 - 2 years 77
2 - 5 years 115
5 - 10 years 41
10 years or more 47
Adherence
Adherence Evaluations
Always 553
Usually 107
Sometimes 21
Never taken as prescribed 16
Burden
Burden Evaluations
Very hard to take 53
Somewhat hard to take 110
A little hard to take 111
Not at all hard to take 423
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 18
$50-99 32
$25-49 57
< $25 273
Not specified 298

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 30
Lamotrigine (Lamictal) 14
Topiramate (Topamax) 11
Aripiprazole (Abilify) 9
Sertraline (Zoloft) 6

Show all 41 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 24
Carbamazepine (Tegretol) 11
Lithium Carbonate (Lithium Carbonate ER) 10
Oxcarbazepine (Trileptal) 9
Levetiracetam (Keppra) 7

Show all 30 treatments patients report switching to

Last updated:

67 patient evaluations for Divalproex sodium

May 10, 2017 (Started Mar 09, 2017)

  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    Severe (Very low white blood cell count)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 500 mg Daily
Advice & Tips: had to sto[ WBC dropped to 3
Cost: < $25 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 250 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 250 mg All the time (24/7)

  • 0 helpful marks

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 67 patient evaluations for Divalproex sodium