What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

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Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 575 271
Bipolar disorder 341 205
Migraine headaches 109 57
Bipolar II disorder 46 33
Bipolar manic episodes 45 34
Bipolar I disorder 44 31

Show all 120 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 170
Moderate 194
Mild 184
None 167

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 136
Hair loss 44
Fatigue 37
Drowsiness 25
Tremor in hands 22
Nausea 17

Show all 267 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
500 mg twice daily 22
1,000 mg daily 20
500 mg daily 19
250 mg twice daily 15
250 mg daily 13
1,500 mg daily 12
750 mg daily 9
500 mg three times daily 7
125 mg daily 5
1,000 mg twice daily 5

See all 25 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 319
Did not seem to work 225
Doctor's advice 158
Other 102
Personal research 35
Expense 30
Course of treatment ended 22
Change in health plan coverage 9
See all 587 patients who've stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
1 - 6 months 14
6 months - 1 year 17
1 - 2 years 21
2 - 5 years 31
5 - 10 years 36
10 years or more 38

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 103
1 - 6 months 136
6 months - 1 year 70
1 - 2 years 78
2 - 5 years 117
5 - 10 years 41
10 years or more 50
Adherence
Adherence Evaluations
Always 565
Usually 109
Sometimes 23
Never taken as prescribed 18
Burden
Burden Evaluations
Very hard to take 54
Somewhat hard to take 112
A little hard to take 112
Not at all hard to take 437
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 18
$50-99 34
$25-49 58
< $25 281
Not specified 305

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 30
Lamotrigine (Lamictal) 14
Topiramate (Topamax) 12
Aripiprazole (Abilify) 8
Sertraline (Zoloft) 6

Show all 41 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 26
Lithium Carbonate (Lithium Carbonate ER) 11
Carbamazepine (Tegretol) 10
Levetiracetam (Keppra) 9
Oxcarbazepine (Trileptal) 9

Show all 31 treatments patients report switching to

Last updated:

67 patient evaluations for Divalproex sodium

Sep 19, 2017 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Moderate (Head pressure)
  • Adherence
    Sometimes
  • Burden
    Somewhat hard to take
Dosage: 500 mg Daily
Cost: < $25 monthly

Apr 9, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for bipolar disorder)
  • Side effects
    Mild (Head pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 10, 2017 (Started Mar 09, 2017)

  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    Severe (Very low white blood cell count)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 500 mg Daily
Advice & Tips: had to sto[ WBC dropped to 3
Cost: < $25 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 250 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 250 mg All the time (24/7)

  • 0 helpful marks
Last updated:
Showing 3 of 67 patient evaluations for Divalproex sodium