What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

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Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 556 262
Bipolar Disorder 315 188
Migraine headaches 106 57
Bipolar manic episodes 45 34
Bipolar I Disorder 41 29
Bipolar II Disorder 41 32

Show all 126 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 158
Moderate 189
Mild 175
None 153

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 131
Hair loss 42
Fatigue 36
Drowsiness 25
Tremor in hands 21
Nausea 18

Show all 256 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
1,000 mg daily 22
500 mg daily 21
500 mg twice daily 18
1,500 mg daily 15
250 mg twice daily 13
250 mg daily 12
500 mg three times daily 9
2,000 mg daily 9
750 mg daily 7
1,000 mg twice daily 5

See all 32 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 303
Did not seem to work 219
Doctor's advice 148
Other 99
Personal research 33
Expense 25
Course of treatment ended 21
Change in health plan coverage 7
See all 555 patients who’ve stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
Less than 1 month 2
1 - 6 months 13
6 months - 1 year 12
1 - 2 years 29
2 - 5 years 35
5 - 10 years 36
10 years or more 37

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 92
1 - 6 months 132
6 months - 1 year 67
1 - 2 years 73
2 - 5 years 113
5 - 10 years 39
10 years or more 47
Adherence
Adherence Evaluations
Always 534
Usually 106
Sometimes 20
Never taken as prescribed 15
Burden
Burden Evaluations
Very hard to take 49
Somewhat hard to take 109
A little hard to take 107
Not at all hard to take 410
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 17
$50-99 29
$25-49 57
< $25 265
Not specified 288

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 27
Lamotrigine (Lamictal) 13
Topiramate (Topamax) 10
Aripiprazole (Abilify) 6
Sertraline (Zoloft) 6

Show all 40 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 21
Carbamazepine (Tegretol) 10
Lithium Carbonate (Lithium Carbonate ER) 8
Levetiracetam (Keppra) 7
Oxcarbazepine (Trileptal) 7

Show all 28 treatments patients report switching to

Last updated:

66 patient evaluations for Divalproex sodium

523 members have decided to share their profiles only with other members of PatientsLikeMe.

Just 4 You
40007 thumb
Just 4 You
Data Quality: 2 stars
  • Gender: M
  • Age: 54y
  • Duration: 52 yrs
PRO survey: PRO 3
Quality of life:
  • Mental: None
  • Physical: Mild
0 seizures
3 weeks ago
I am: vg
I have:
Epilepsy

See Just 4 You's full Divalproex sodium history

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for Epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
crine312
21539 thumb
crine312
Gender: M
Data Quality: 1 star
Depression: 3
Mania: 1
Emotional: 3
Anxiety: 2
Compulsion: 3
External Stress: Severe
39 M
Function: Moderate
Distress: Moderate
I am: b
I have:
PTSD

See crine312's full Divalproex sodium history

Apr 9, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for Bipolar Disorder)
  • Side effects
    Mild (Head pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
wealth22
36923 thumb
wealth22
Data Quality: 2 stars
  • Gender: M
  • Age: 49y
  • Duration: 48 yrs
Quality of life:
  • Mental: Mild
  • Physical: Mild
14 seizures
62 weeks ago
I am: vg
I have:
Epilepsy

See wealth22's full Divalproex sodium history

Jan 2, 2016 (Started Apr 07, 2011)

  • Effectiveness
    Slight (for Epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1500 mg Daily
Advice & Tips: In order to stay on top of never missing a dose, I set my alarm on my iPhone as well as downloaded an app called Mango Health. It is free and very easy to use.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 66 patient evaluations for Divalproex sodium