What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

false

Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 553 259
Bipolar Disorder 304 180
Migraine headaches 106 55
Bipolar manic episodes 45 34
Bipolar I Disorder 41 29
Bipolar II Disorder 39 30

Show all 126 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 157
Moderate 186
Mild 172
None 149

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 129
Hair loss 41
Fatigue 35
Drowsiness 25
Tremor in hands 21
Nausea 18

Show all 252 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
500 mg daily 23
1,000 mg daily 19
500 mg twice daily 19
1,500 mg daily 17
250 mg daily 14
250 mg twice daily 10
500 mg three times daily 10
2,000 mg daily 7
750 mg daily 5
1,000 mg twice daily 4

See all 31 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 296
Did not seem to work 213
Doctor's advice 146
Other 96
Personal research 32
Expense 25
Course of treatment ended 20
Change in health plan coverage 7
See all 541 patients who’ve stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
Less than 1 month 1
1 - 6 months 10
6 months - 1 year 14
1 - 2 years 27
2 - 5 years 37
5 - 10 years 34
10 years or more 35

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 91
1 - 6 months 132
6 months - 1 year 63
1 - 2 years 70
2 - 5 years 112
5 - 10 years 37
10 years or more 45
Adherence
Adherence Evaluations
Always 526
Usually 105
Sometimes 19
Never taken as prescribed 14
Burden
Burden Evaluations
Very hard to take 49
Somewhat hard to take 108
A little hard to take 106
Not at all hard to take 401
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 17
$50-99 29
$25-49 56
< $25 260
Not specified 283

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 23
Lamotrigine (Lamictal) 13
Topiramate (Topamax) 10
Aripiprazole (Abilify) 6
Sertraline (Zoloft) 6

Show all 41 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 18
Carbamazepine (Tegretol) 9
Lithium Carbonate (Lithium Carbonate ER) 8
Levetiracetam (Keppra) 7
Oxcarbazepine (Trileptal) 7

Show all 27 treatments patients report switching to

Last updated:

66 patient evaluations for Divalproex sodium

516 members have decided to share their profiles only with other members of PatientsLikeMe.

Just 4 You
40007 thumb
Just 4 You
Data Quality: 2 stars
  • Gender: M
  • Age: 54y
  • Duration: 52 yrs
PRO survey: PRO 3
Quality of life:
  • Mental: None
  • Physical: Mild
0 seizures
this week
I am: vg
I have:
Epilepsy

See Just 4 You's full Divalproex sodium history

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for Epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
crine312
21539 thumb
crine312
Gender: M
Data Quality: 1 star
Depression: 3
Mania: 1
Emotional: 3
Anxiety: 2
Compulsion: 3
External Stress: Severe
38 M
Function: Moderate
Distress: Moderate
I am: b
I have:
PTSD

See crine312's full Divalproex sodium history

Apr 9, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for Bipolar Disorder)
  • Side effects
    Mild (Head pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
wealth22
36923 thumb
wealth22
Data Quality: 2 stars
  • Gender: M
  • Age: 49y
  • Duration: 48 yrs
Quality of life:
  • Mental: Mild
  • Physical: Mild
14 seizures
54 weeks ago
I am: vg
I have:
Epilepsy

See wealth22's full Divalproex sodium history

Jan 2, 2016 (Started Apr 07, 2011)

  • Effectiveness
    Slight (for Epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1500 mg Daily
Advice & Tips: In order to stay on top of never missing a dose, I set my alarm on my iPhone as well as downloaded an app called Mango Health. It is free and very easy to use.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 66 patient evaluations for Divalproex sodium