What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

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Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 550 255
Bipolar Disorder 271 155
Migraine headaches 99 50
Bipolar manic episodes 45 34
Bipolar I Disorder 42 27
Bipolar II Disorder 38 30

Show all 117 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 148
Moderate 179
Mild 161
None 139

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 123
Hair loss 41
Fatigue 34
Drowsiness 24
Tremor in hands 19
Nausea 17

Show all 235 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
1,000 mg daily 14
500 mg daily 12
250 mg daily 11
500 mg twice daily 11
250 mg twice daily 8
500 mg three times daily 8
1,500 mg daily 7
750 mg daily 5
125 mg daily 3
1,250 mg daily 3

See all 29 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 286
Did not seem to work 210
Doctor's advice 143
Other 89
Personal research 30
Expense 24
Course of treatment ended 20
Change in health plan coverage 6
See all 523 patients who’ve stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
1 - 6 months 4
6 months - 1 year 9
1 - 2 years 18
2 - 5 years 30
5 - 10 years 21
10 years or more 27

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 88
1 - 6 months 129
6 months - 1 year 62
1 - 2 years 66
2 - 5 years 108
5 - 10 years 33
10 years or more 45
Adherence
Adherence Evaluations
Always 500
Usually 97
Sometimes 16
Never taken as prescribed 14
Burden
Burden Evaluations
Very hard to take 46
Somewhat hard to take 105
A little hard to take 105
Not at all hard to take 371
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 15
$50-99 27
$25-49 55
< $25 246
Not specified 265

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 18
Lamotrigine (Lamictal) 12
Topiramate (Topamax) 8
Sertraline (Zoloft) 5
Aripiprazole (Abilify) 4

Show all 38 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 13
Carbamazepine (Tegretol) 9
Levetiracetam (Keppra) 7
Lithium Carbonate (Lithium Carbonate ER) 6
Oxcarbazepine (Trileptal) 6

Show all 26 treatments patients report switching to

Last updated:

67 patient evaluations for Divalproex sodium

484 members have decided to share their profiles only with other members of PatientsLikeMe.

Just 4 You
40007 thumb
Just 4 You
Data Quality: 2 stars
  • Gender: M
  • Age: 54y
  • Duration: 51 yrs
PRO survey: PRO 3
Quality of life:
  • Mental: None
  • Physical: Mild
0 seizures
7 weeks ago
I am: g
I have:
Epilepsy

See Just 4 You's full Divalproex sodium history

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for Epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
scorpio1975
34967 thumb
scorpio1975
Gender: F
Data Quality: 1 star
Pain: All
Fatigue: All
Sleep: Most
Stiffness: All
function: None
external_stress: All
Stickman: all
Description:F41y
FM:27y Dx
I am: vb
I have:
Fibromyalgia

See scorpio1975's full Divalproex sodium history

May 9, 2016 (Started Jul 01, 2010)

  • Effectiveness
    Major (for Schizoaffective Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Twice daily
Advice & Tips: Dont stop taking it!

  • 0 helpful marks
crine312
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crine312
Gender: M
Data Quality: 2 stars
Depression: 3
Mania: 1
Emotional: 3
Anxiety: 2
Compulsion: 3
External Stress: Severe
38 M
Function: Moderate
Distress: Moderate
I am: b
I have:
PTSD

See crine312's full Divalproex sodium history

Apr 9, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Slight (for Bipolar Disorder)
  • Side effects
    Mild (Head pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 250 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 67 patient evaluations for Divalproex sodium