What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar disorder 1,544 896
Epilepsy 1,103 530
Bipolar II disorder 781 471
Bipolar I disorder 458 285
Depressed mood 163 111
Major depressive disorder 157 125

Show all 206 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 273
Moderate 420
Mild 605
None 976

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Weight gain 78
Dizziness 70
Headaches 69
Rashes (redness, swelling) 52
Nausea 50
Fatigue 47

Show all 513 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 128
100 mg daily 79
150 mg daily 54
25 mg daily 53
300 mg daily 45
200 mg twice daily 38
400 mg daily 33
50 mg daily 30
100 mg twice daily 29
150 mg twice daily 22

See all 61 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 462
Did not seem to work 406
Doctor's advice 277
Other 200
Expense 68
Personal research 54
Course of treatment ended 43
Change in health plan coverage 35
See all 1042 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 2
1 - 6 months 27
6 months - 1 year 55
1 - 2 years 96
2 - 5 years 173
5 - 10 years 182
10 years or more 97

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 240
1 - 6 months 241
6 months - 1 year 158
1 - 2 years 140
2 - 5 years 169
5 - 10 years 93
10 years or more 17
Adherence
Adherence Evaluations
Always 1862
Usually 285
Sometimes 50
Never taken as prescribed 77
Burden
Burden Evaluations
Very hard to take 97
Somewhat hard to take 207
A little hard to take 370
Not at all hard to take 1600
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 49
$50-99 66
$25-49 121
< $25 1052
Not specified 944

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 101
Divalproex sodium (Depakote) 49
Quetiapine (Seroquel) 48
Aripiprazole (Abilify) 44
Bupropion (Wellbutrin XL) 24

Show all 53 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 37
Aripiprazole (Abilify) 27
Quetiapine (Seroquel) 20
Divalproex sodium (Depakote) 16
Lurasidone (Latuda) 14

Show all 62 treatments patients report switching to

Last updated:

140 patient evaluations for Lamotrigine

Dec 30, 2017 (Started Feb 15, 2015)

  • Effectiveness
    Major (for bipolar mixed episodes)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for seizures)
  • Effectiveness
    Can't tell (for epilepsy)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for seizures)
  • Effectiveness
    Slight (for epilepsy)
  • Side effects
    Severe (loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Major (for bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for depressed mood)
  • Effectiveness
    Major (for bipolar rapid cycling)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

  • 0 helpful marks
Last updated:
Showing 3 of 140 patient evaluations for Lamotrigine