What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 1,228 682
Epilepsy 1,064 490
Bipolar II Disorder 622 364
Bipolar I Disorder 383 236
Depressed mood 143 95
Borderline Personality Disorder 131 76

Show all 209 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 218
Moderate 360
Mild 510
None 777

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 66
Headaches 61
Weight gain 55
Nausea 46
Insomnia 44
Problems concentrating 44

Show all 491 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 111
100 mg daily 73
25 mg daily 50
150 mg daily 50
300 mg daily 43
200 mg twice daily 38
100 mg twice daily 36
50 mg daily 32
400 mg daily 32
150 mg twice daily 21

See all 63 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 385
Did not seem to work 359
Doctor's advice 242
Other 175
Expense 62
Personal research 50
Course of treatment ended 36
Change in health plan coverage 31
See all 894 patients who’ve stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 5
1 - 6 months 42
6 months - 1 year 68
1 - 2 years 97
2 - 5 years 151
5 - 10 years 160
10 years or more 89

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 181
1 - 6 months 223
6 months - 1 year 142
1 - 2 years 123
2 - 5 years 147
5 - 10 years 79
10 years or more 15
Adherence
Adherence Evaluations
Always 1517
Usually 249
Sometimes 39
Never taken as prescribed 60
Burden
Burden Evaluations
Very hard to take 81
Somewhat hard to take 174
A little hard to take 315
Not at all hard to take 1295
Cost per month
Cost per month Evaluations
$200+ 40
$100-199 45
$50-99 61
$25-49 108
< $25 877
Not specified 734

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 62
Quetiapine (Seroquel) 32
Aripiprazole (Abilify) 30
Divalproex sodium (Depakote) 30
Carbamazepine (Tegretol) 15

Show all 49 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 25
Quetiapine (Seroquel) 16
Aripiprazole (Abilify) 15
Divalproex sodium (Depakote) 9
Oxcarbazepine (Trileptal) 9

Show all 45 treatments patients report switching to

Last updated:

137 patient evaluations for Lamotrigine

1,428 members have decided to share their profiles only with other members of PatientsLikeMe.

zoomer
60535 thumb
zoomer
Gender: F
Data Quality: 3 stars
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: vg
I have:
Bipolar I

See zoomer's full Lamotrigine history

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar I Disorder)
  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Bipolar Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
Christina22222
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Christina22222
Data Quality: 3 stars
  • Gender: F
  • Age: 45
Condition: TBI 3 additional condition(s)
Quality of life:
  • Mental: None
  • Physical: None
I am: vg
I have:
TBI

See Christina22222's full Lamotrigine history

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Slight (for Epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks
charkimber
50769 thumb
charkimber
Gender: F
Data Quality: 3 stars
Depression: 3
Mania: 2
Emotional: 3
Anxiety: 3
Compulsion: 3
External Stress: Moderate
56 F
Function: Low
Distress: High
I am: g
I have:
Bipolar II

See charkimber's full Lamotrigine history

Jan 18, 2017 (Started Jul 01, 2009)

  • Effectiveness
    Major (for Bipolar II Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Don't go off without talking to doctor. I came out of the fog after starting this medication.

  • 0 helpful marks
Last updated:
Showing 3 of 137 patient evaluations for Lamotrigine