What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,738 995
Depressed mood 1,504 713
Persistent depressive disorder (dysthymia) 328 278
Mild Depression 138 55
Anxious mood 114 54
Bipolar Disorder 100 84

Show all 203 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 225
Moderate 323
Mild 525
None 910

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 89
Anxious mood 54
Weight gain 46
Insomnia 45
Constipation 40
Headaches 39

Show all 401 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 114
150 mg daily 113
300 mg/24 hours daily 73
100 mg daily 68
450 mg daily 38
75 mg daily 36
100 mg twice daily 35
150 mg/24 hours daily 31
200 mg daily 22
150 mg twice daily 18

See all 65 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 549
Side effects too severe 469
Doctor's advice 360
Other 245
Course of treatment ended 78
Expense 78
Personal research 67
Change in health plan coverage 36
See all 1358 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 6
1 - 6 months 40
6 months - 1 year 60
1 - 2 years 106
2 - 5 years 161
5 - 10 years 173
10 years or more 124

Stopped taking Bupropion

Duration Patients
Less than 1 month 268
1 - 6 months 327
6 months - 1 year 213
1 - 2 years 199
2 - 5 years 237
5 - 10 years 108
10 years or more 46
Adherence
Adherence Evaluations
Always 1551
Usually 312
Sometimes 44
Never taken as prescribed 76
Burden
Burden Evaluations
Very hard to take 68
Somewhat hard to take 121
A little hard to take 301
Not at all hard to take 1493
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 25
$50-99 77
$25-49 154
< $25 967
Not specified 750

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 60
Fluoxetine (Prozac) 50
Venlafaxine (Effexor XR) 47
Duloxetine (Cymbalta) 37
Citalopram (Celexa) 27

Show all 38 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 36
Sertraline (Zoloft) 29
Venlafaxine (Effexor XR) 19
Citalopram (Celexa) 16
Escitalopram (Lexapro) 16

Show all 39 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

1,509 members have decided to share their profiles only with other members of PatientsLikeMe.

zoomer
60535 thumb
zoomer
Gender: F
Data Quality: 3 stars
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 0
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: vg
I have:
Bipolar I

See zoomer's full Bupropion history

Feb 6, 2017 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines. I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking Wellbutrin. I don't allocate all credit to this med. I take Trintellix also.I have noticed a more consistent level of lower anxiety on Wellbutrin.
Cost: < $25 monthly

Nov 29, 2015 (Started Dec 04, 2009)

  • Effectiveness
    None (for Tobacco Addiction)
  • Effectiveness
    Moderate (for Major Depressive Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: Just wanting to update. I continue taking Wellbutrin daily in the morning. I have many helpful strategies for reducing anxiety. Pair those coping skills with this medication, I have been able to avoid the benzodiazepines.
Cost: < $25 monthly

Apr 6, 2011 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I initially asked Pdoc for this med to assist my stop smoking nicotine efforts. The effects of the anti-anxiety component were noticeable behaviorally: symptoms reduced and intensity of symptoms lessened. As far as helping with my depression, I have been without an episode of major depression for as long as I have been taking wellbutrin. I don't allocate all credit to this med. I take Pristiq also. So, did it help me quit smoking? not yet.
Cost: < $25 monthly

Oct 25, 2010 (Started Dec 04, 2009)

  • Effectiveness
    Can’t tell (for Bipolar Disorder)
  • Effectiveness
    Slight (for Depressed mood)
  • Effectiveness
    Moderate (for Anxious mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I have noticed a more consistent level of lower anxiety on Wellbutrin. It has also noticeably helped decrease the depression a degree during episodes. I have also decreased my tabacco intake since taking .
Cost: < $25 monthly

  • 1 helpful mark
CupcakeKitten
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CupcakeKitten
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 0
Emotional: 2
Anxiety: 2
Compulsion: 1
External Stress: Moderate
25 F
Function: Moderate
Distress: Low
I am: b
I have:
Borderline Personality

See CupcakeKitten's full Bupropion history

Jan 13, 2017 (Started Dec 06, 2016)

  • Effectiveness
    Slight (for Lack of motivation)
  • Effectiveness
    Slight (for Exhaustion)
  • Effectiveness
    Slight (for Excessive sleeping (hypersomnia))
  • Side effects
    Moderate (Muscle twitching (fasciculations), Impulsive behaviors)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
gridly1
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gridly1
Gender: F
Data Quality: 2 stars
Pain: Little
Fatigue: Some
Sleep: All
Stiffness: All
function: None
external_stress: Most
Stickman: most
Description:F57y
CFS:?y
FM:8y Dx
I am: b
I have:
ME/CFS

See gridly1's full Bupropion history

Nov 1, 2016 (Started Aug 19, 2016)

  • Effectiveness
    None (for Persistent depressive disorder (dysthymia))
  • Side effects
    Severe (Serotonin syndrome, Night sweats, Unrefreshing or poor sleep, Constipation, Shakiness, Hot flashes, Brain fog)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion