What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,212 1,255
Depressed mood 1,591 781
Persistent depressive disorder (dysthymia) 386 316
Mild depression 152 65
Anxious mood 122 67

Show all 193 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 263
Moderate 375
Mild 599
None 1,100

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 104
Anxious mood 69
Weight gain 55
Insomnia 49
Headaches 46
Constipation 43

Show all 439 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 166
150 mg daily 131
100 mg daily 86
300 mg/24 hours daily 56
450 mg daily 51
75 mg daily 48
150 mg twice daily 35
100 mg twice daily 28
200 mg daily 27
150 mg/24 hours daily 21

See all 66 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 637
Side effects too severe 539
Doctor's advice 413
Other 271
Course of treatment ended 88
Expense 81
Personal research 70
Change in health plan coverage 40
See all 1558 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 86
6 months - 1 year 67
1 - 2 years 110
2 - 5 years 189
5 - 10 years 178
10 years or more 157

Stopped taking Bupropion

Duration Patients
Less than 1 month 329
1 - 6 months 354
6 months - 1 year 243
1 - 2 years 225
2 - 5 years 269
5 - 10 years 120
10 years or more 57
Adherence
Adherence Evaluations
Always 1824
Usually 351
Sometimes 53
Never taken as prescribed 109
Burden
Burden Evaluations
Very hard to take 78
Somewhat hard to take 147
A little hard to take 335
Not at all hard to take 1777
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 24
$50-99 84
$25-49 170
< $25 1129
Not specified 917

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 91
Fluoxetine (Prozac) 83
Venlafaxine (Effexor XR) 65
Citalopram (Celexa) 49
Duloxetine (Cymbalta) 47

Show all 56 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 45
Sertraline (Zoloft) 44
Venlafaxine (Effexor XR) 33
Citalopram (Celexa) 30
Fluoxetine (Prozac) 27

Show all 45 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

Sep 19, 2017 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Mild (headaches)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 300 mg Daily
Cost: < $25 monthly

Sep 17, 2012 (Started Apr 10, 2012)

  • Effectiveness
    Slight (for complex post-traumatic stress disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (headaches)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Advice & Tips: Have someone you trust remind you to take the medicines. I have my wife who reminds me, although I have the medicine in the cupboard by the glasses. When I experience headaches with the buproprion, I take some Aleve or Motrin.
Cost: < $25 monthly

  • 0 helpful marks

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion