What is Sulfamethoxazole-Trimethoprim (cotrimoxazole)?

Category: Prescription Drugs

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Sulfamethoxazole-trimethoprim, also known as SMX-TMP or cotrimoxazole, is a combination of sulfamethoxazole, an antibacterial sulfonamide, and trimethoprim. The combination eliminates bacteria that cause many kinds of infections, including pneumonia and urinary tract and intestinal infections.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent infection 180 80
Urinary tract infection 65 42
Sinus infection (sinusitis) 20 6
Human immunodeficiency virus (HIV) 16 4
General health 15 6

Show all 73 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
15
Moderate
11
Mild
45
None
136

Commonly reported side effects and conditions associated with Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Side effect Patients
Nausea 7
Diarrhea 5
Abdominal cramps 2
Alternating constipation and diarrhea 2
Vaginal yeast infection 2
Allergic reaction 1

Show all 63 reported side effects

Dosages

Based on patients currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Dosage Patients
400-80 mg daily 6
400 mg-80 mg daily 5
800-160 mg daily 5
400 mg-80 mg m,w,f 2
800-160 mg m,w,f 2
400 mg-80 mg twice daily 2
800 mg-160 mg daily 2
800-160 mg twice daily 2
800-160 mg three times daily 2
1 tablet(s) m,w,f 1

See all 26 dosages

Why patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Multiple reasons could be selected

Reason Patients
Course of treatment ended 148
Doctor's advice 58
Side effects too severe 28
Did not seem to work 12
Other 11
Personal research 1
See all 227 patients who've stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration

Currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients
Less than 1 month 1
1 - 6 months 5
6 months - 1 year 5
1 - 2 years 8
2 - 5 years 14
5 - 10 years 13

Stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Duration Patients
Less than 1 month 109
1 - 6 months 52
6 months - 1 year 30
1 - 2 years 22
2 - 5 years 10
5 - 10 years 5
10 years or more 3
Adherence
Adherence Evaluations
Always 174
Usually 17
Sometimes 7
Never taken as prescribed 9
Burden
Burden Evaluations
Very hard to take 7
Somewhat hard to take 9
A little hard to take 30
Not at all hard to take 161
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 1
$25-49 10
< $25 106
Not specified 90

What people switch to and from

Patients started taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) after stopping:

Treatment Patients
Cephalexin (Keflex) 2
Clarithromycin (Biaxin) 2
Amoxicillin-clavulanate (Augmentin) 1
Azithromycin (Zithromax) 1
Ciprofloxacin (Cipro) 1

Show all 9 treatments patients report switching from

Patients stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) and switched to:

Treatment Patients
Amoxicillin (Amoxil) 1
Artemether-lumefantrine 1
Atovaquone (Mepron) 1
Cefuroxime (Ceftin) 1
Cephalexin (Keflex) 1

Show all 14 treatments patients report switching to

Last updated:

25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Aug 23, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for cysts)
  • Side effects
    Mild (nausea, upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Advice & Tips: Cyst is almost gone
Cost: < $25 monthly

Aug 19, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for cysts)
  • Side effects
    Mild (nausea, upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Advice & Tips: My stomach feels upset from time to time on days when I take this. The cyst I'm taking this for has shrunk, could be gone in a week.
Cost: < $25 monthly

Aug 15, 2016 (Started Aug 12, 2016)

  • Effectiveness
    Major (for cysts)
  • Side effects
    Mild (nausea, upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 800-160 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks

Jan 6, 2014 (Started Dec 13, 2013)

  • Effectiveness
    Moderate (for urinary tract infection)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Cost: < $25 monthly

Dec 26, 2013 (Started Dec 13, 2013)

  • Effectiveness
    Moderate (for urinary tract infection)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 2 x 200 mg-40 mg/5 mL Daily
Cost: < $25 monthly

  • 0 helpful marks

Dec 23, 2012 (Started Dec 22, 2012)

  • Effectiveness
    Moderate (for urinary tract infection)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 1200 mg Daily
Advice & Tips: good for clearing Urinary infection
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 25 patient evaluations for Sulfamethoxazole-Trimethoprim (cotrimoxazole)