What is Vortioxetine?

Category: Prescription Drugs

Most popular types: Trintellix

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Vortioxetine is a novel and atypical antidepressant used for the treatment of major depressive disorder. The drug acts as a modulator and stimulator of serotonin, a chemical in the body generally associated with well-being and happiness.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 133 123
Generalized anxiety disorder 37 35
Depressed mood 27 16
Bipolar II disorder 7 6
Post-traumatic stress disorder 4 1
Fibromyalgia 3 6

Show all 30 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 27
Moderate 33
Mild 43
None 47

Commonly reported side effects and conditions associated with Vortioxetine

Side effect Patients
Nausea 21
Anxious mood 5
Diarrhea 5
Headaches 5
Constipation 4
Decreased sex drive (libido) 4

Show all 72 reported side effects

Dosages

Based on patients currently taking Vortioxetine

Dosage Patients
20 mg daily 32
10 mg daily 18
5 mg daily 11
15 mg daily 2
1 mg twice daily 1
2 mg daily 1
2.5 mg daily 1
5 mg twice daily 1

Why patients stopped taking Vortioxetine

Multiple reasons could be selected

Reason Patients
Did not seem to work 38
Side effects too severe 27
Doctor's advice 21
Expense 13
Other 12
Personal research 4
Change in health plan coverage 2
Course of treatment ended 2
See all 75 patients who've stopped taking Vortioxetine

Duration

Currently taking Vortioxetine

Duration Patients
Less than 1 month 1
1 - 6 months 11
6 months - 1 year 14
1 - 2 years 20
2 - 5 years 20
10 years or more 1

Stopped taking Vortioxetine

Duration Patients
Less than 1 month 22
1 - 6 months 27
6 months - 1 year 15
1 - 2 years 7
2 - 5 years 4
Adherence
Adherence Evaluations
Always 133
Usually 11
Sometimes 1
Never taken as prescribed 5
Burden
Burden Evaluations
Very hard to take 8
Somewhat hard to take 6
A little hard to take 10
Not at all hard to take 126
Cost per month
Cost per month Evaluations
$200+ 8
$100-199 8
$50-99 20
$25-49 12
< $25 60
Not specified 42

What people switch to and from

Patients started taking Vortioxetine after stopping:

Treatment Patients
Venlafaxine (Effexor XR) 18
Sertraline (Zoloft) 15
Bupropion (Wellbutrin XL) 13
Escitalopram (Lexapro) 13
Citalopram (Celexa) 12

Show all 27 treatments patients report switching from

Patients stopped taking Vortioxetine and switched to:

Treatment Patients
Duloxetine (Cymbalta) 8
Escitalopram (Lexapro) 4
Fluoxetine (Prozac) 4
Sertraline (Zoloft) 4
Venlafaxine (Effexor XR) 4

Show all 19 treatments patients report switching to

Last updated:

4 patient evaluations for Vortioxetine

Feb 21, 2018 (Started Jun 15, 2016)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for depressed mood)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily

  • 0 helpful marks

Feb 5, 2018 (Started Dec 19, 2017)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: It seem to take a long time, about two months, before I notice any positive change. But after about two months I am feeling better. I wanted to increase the dosage to fast, and I started going manic, so I had to bring the dosage back down.
Cost: < $25 monthly

  • 0 helpful marks

Jan 13, 2018 (Started Jul 15, 2016)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Moderate (for bipolar II disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Ask doc for a coupon!
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 4 patient evaluations for Vortioxetine