What is Tecfidera?

Category: Prescription Drugs

true

Generic name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness

Purpose
Patients
Patients with evaluations
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Purpose
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 43
Moderate 35
Mild 111
None 65

Commonly reported side effects and conditions associated with Tecfidera

Side effect Patients
Flushing 81
Facial flushing 37
Diarrhea 34
Nausea 20
Stomach pain 19
Stomach upset 16

Show all 168 reported side effects

Dosages

Based on patients currently taking Tecfidera

Dosage Patients
240 mg twice daily 54
480 mg daily 25
240 mg daily 17
120 mg twice daily 16
2 capsule(s) daily 11
120 mg daily 10
1 capsule(s) twice daily 8
2 capsule(s) twice daily 5
2 tablet(s) daily 4
1 capsule(s) daily 3

See all 45 dosages

Why patients stopped taking Tecfidera

Multiple reasons could be selected

Reason Patients
Side effects too severe 61
Doctor's advice 32
Did not seem to work 20
Other 9
Course of treatment ended 1
Personal research 1
See all 92 patients who’ve stopped taking Tecfidera

Duration

Currently taking Tecfidera

Duration Patients
0-1 month 1
1-3 months 4
3-6 months 14
6 months-1 year 24
1-2 years 68
2 years or more 90

Stopped taking Tecfidera

Duration Patients
0-1 month 16
1-3 months 16
3-6 months 13
6 months-1 year 21
1-2 years 18
2 years or more 7
1

Adherence


Always
Patients
203
80%
Usually
Patients
40
16%
Sometimes
Patients
4
2%
Never taken as prescribed
Patients
7
3%

Burden


Very hard to take
Patients
8
3%
Somewhat hard to take
Patients
16
6%
A little hard to take
Patients
35
14%
Not at all hard to take
Patients
195
77%

Cost per month


Cost per month
$200+
Patients
10
4%
Cost per month
$100-199
Patients
3
1%
Cost per month
$50-99
Patients
11
4%
Cost per month
$25-49
Patients
24
9%
Cost per month
< $25
Patients
121
48%
Cost per month
Not specified
Patients
85
33%

What people switch to and from

Patients started taking Tecfidera after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 40
Interferon beta-1a IM Injection (Avonex) 25
Interferon beta-1a SubQ injection (Rebif) 22
Interferon beta-1b SubQ Injection (Betaseron) 15
Natalizumab (Tysabri) 13

Show all 12 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:

Treatment Patients
Glatiramer acetate (Copaxone) 14
Teriflunomide (Aubagio) 13
Natalizumab (Tysabri) 11
Peginterferon beta-1a (Plegridy) 4
Fingolimod (Gilenya) 3

Show all 13 treatments patients report switching to

Last updated:

20 patient evaluations for Tecfidera

nsingle1
62264 thumb
nsingle1
Sex: F
Data Quality: 3 stars
Sensation: Mild
Overall: Mild
Cognition: mild
Vision: none
Speech: none
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: g
I have:
MS

See nsingle1's full Tecfidera history

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 0 helpful marks
grllongoria
59441 thumb
grllongoria
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: None
Cognition: none
Vision: none
Speech: none
Swallowing: none
Upper limb: none
Walking: severe
I am: g
I have:
MS

See grllongoria's full Tecfidera history

Feb 18, 2016 (Started Apr 30, 2013)

  • Effectiveness
    Slight (for Multiple Sclerosis)
  • side effects
    Mild (Flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: Past 2 MRI's have shown new lesions. This last MRI showed 1 new active lesion which caused a relapse was treated with steroids. Took a long while to get back to my normal.
Cost: < $25 monthly

Jun 19, 2013 (Started Apr 30, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • side effects
    Mild (Flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: I have felt 2 heavy legs numb, lifeless limbs right one dragged tripping me a lot for years. Another was a very painful area on my right thigh my granddaughters could not sit on my lap it was a burning sensation constantly. Nothing helped it. Three weeks into Tecfidera my legs feel lighter not as numb and no dragging. Feet and toes also more movement. Painful area totally gone. Walking also improved. Started week 7 June 18 and continue to have the flushing and itchy skin about once a day but this is very tolerable. Try hard to take this with food

  • 1 helpful mark
thjuland
647 thumb
thjuland
Sex: M
Data Quality: 3 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: none
Speech: none
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: vg
I have:
MS

See thjuland's full Tecfidera history

Jan 25, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I feel my JC virus titer level is high at 2.14, but there is presently no other drug with a safer side-effect profile, so I'm waiting for the next approved MS medication to switch to:-(
Cost: < $25 monthly

Feb 26, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: Tuesday's MRI is clear (no new or active lesions), so will continue with this medication.
Cost: < $25 monthly

Jan 14, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I must eat a meal with meat or I'll throw-up.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 20 patient evaluations for Tecfidera