What is Tecfidera?

Category: Prescription Drugs

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Generic name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple Sclerosis 529 497
Drug ineffective 5 3
Allergic reaction 2 4
Psoriasis 2 2
Arthritis pain 1 0
Brain Atrophy Cerebrum 1 0

Show all 17 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 67
Moderate 79
Mild 228
None 125

Commonly reported side effects and conditions associated with Tecfidera

Side effect Patients
Flushing 106
Facial flushing 40
Diarrhea 38
Nausea 27
Stomach pain 25
Upset stomach 16

Show all 185 reported side effects

Dosages

Based on patients currently taking Tecfidera

Dosage Patients
240 mg twice daily 56
120 mg twice daily 23
480 mg daily 23
240 mg daily 18
120 mg daily 8
2 capsule(s) daily 7
480 mg twice daily 6
2 tablet(s) daily 4
1 capsule(s) daily 3
1 capsule(s) twice daily 3

See all 28 dosages

Why patients stopped taking Tecfidera

Multiple reasons could be selected

Reason Patients
Side effects too severe 73
Doctor's advice 39
Did not seem to work 30
Other 15
Course of treatment ended 3
Change in health plan coverage 2
Expense 2
Personal research 1
See all 121 patients who’ve stopped taking Tecfidera

Duration

Currently taking Tecfidera

Duration Patients
Less than 1 month 1
1 - 6 months 16
6 months - 1 year 15
1 - 2 years 34
2 - 5 years 114
5 - 10 years 1

Stopped taking Tecfidera

Duration Patients
Less than 1 month 20
1 - 6 months 33
6 months - 1 year 24
1 - 2 years 28
2 - 5 years 15
Adherence
Adherence Evaluations
Always 402
Usually 73
Sometimes 7
Never taken as prescribed 17
Burden
Burden Evaluations
Very hard to take 12
Somewhat hard to take 32
A little hard to take 71
Not at all hard to take 384
Cost per month
Cost per month Evaluations
$200+ 18
$100-199 3
$50-99 16
$25-49 44
< $25 256
Not specified 162

What people switch to and from

Patients started taking Tecfidera after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 58
Interferon beta-1a IM Injection (Avonex) 33
Interferon beta-1a SubQ injection (Rebif) 31
Natalizumab (Tysabri) 18
Interferon beta-1b SubQ Injection (Betaseron) 17

Show all 14 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:

Treatment Patients
Teriflunomide (Aubagio) 18
Glatiramer acetate (Copaxone) 17
Natalizumab (Tysabri) 14
Fingolimod (Gilenya) 6
Interferon beta-1a SubQ injection (Rebif) 5

Show all 14 treatments patients report switching to

Last updated:

23 patient evaluations for Tecfidera

305 members have decided to share their profiles only with other members of PatientsLikeMe.

1955chevy
27671 thumb
1955chevy
Sex: M
Data Quality: 3 stars
Sensation: Mild
Overall: Mild
Cognition: mild
Vision: mild
Speech: none
Swallowing: none
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See 1955chevy's full Tecfidera history

Dec 8, 2016 (Started Nov 10, 2015)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • Side effects
    Mild (Facial flushing, Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: One pill twice a day, no problem. Occasional minor face flushing, maybe once or twice a month.
Cost: < $25 monthly

Sep 1, 2016 (Started Nov 10, 2015)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: Almost a year now and no lingering side effects.
Cost: < $25 monthly

Nov 24, 2015 (Started Nov 10, 2015)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    Mild (Facial flushing, Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: Eat something before taking the morning dose. I take the night dose right before bed. The stomach and flushing issues seem to be fading away now after entering the third week. Great to be away from the injections as I was having site issues after 17 years. Although in secondary progressive, Doc agreed with the decision the switch. Biogen is waving the $75 co-pay for me.
Cost: < $25 monthly

  • 1 helpful mark
Mamaw5
30389 thumb
Mamaw5
Sex: F
Data Quality: 3 stars
Sensation: None
Overall: Mild
Cognition: moderate
Vision: none
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See Mamaw5's full Tecfidera history

Dec 1, 2016 (Started Nov 08, 2016)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    Severe (Vomiting)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Advice & Tips: Ive had to stop taking the full dose due to stomach issues and vomiting.
Cost: < $25 monthly

Nov 25, 2016 (Started Nov 08, 2016)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    Severe (Vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: I took it with full meals, I took it with peanut butter...nothing helped and the stomach pain and vomiting were too much. The starter pack of 120mg was ok. But as soon as I started on the full dose, the stomach pain began until it ended up after a few days with severe vomiting.
Cost: < $25 monthly

  • 0 helpful marks
princess60548
33189 thumb
princess60548
Sex: F
Data Quality: 0 stars
Sensation: Moderate
Overall: None
Cognition: mild
Vision: none
Speech: none
Swallowing: none
Upper limb: none
Walking: moderate
I am: n
I have:
MS

See princess60548's full Tecfidera history

Nov 20, 2016 (Started Nov 15, 2016)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side effects
    Mild (Feeling sick)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Four times daily

  • 0 helpful marks
Last updated:
Showing 3 of 23 patient evaluations for Tecfidera