What is Tecfidera?

Category: Prescription Drugs

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Generic name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple Sclerosis 486 434
Drug ineffective 5 3
Vitamin B12 deficiency 2 4
Allergic reaction 1 1
Arthritis pain 1 0
Brain Atrophy Cerebrum 1 0

Show all 17 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 60
Moderate 65
Mild 197
None 114

Commonly reported side effects and conditions associated with Tecfidera

Side effect Patients
Flushing 91
Facial flushing 38
Diarrhea 36
Stomach pain 22
Nausea 20
Stomach upset 16

Show all 171 reported side effects

Dosages

Based on patients currently taking Tecfidera

Dosage Patients
240 mg twice daily 50
480 mg daily 23
120 mg twice daily 18
240 mg daily 15
2 capsule(s) daily 8
2 capsule(s) twice daily 6
120 mg daily 6
1 capsule(s) twice daily 5
2 tablet(s) daily 5
1 tablet(s) twice daily 3

See all 39 dosages

Why patients stopped taking Tecfidera

Multiple reasons could be selected

Reason Patients
Side effects too severe 63
Doctor's advice 33
Did not seem to work 23
Other 13
Course of treatment ended 1
Personal research 1
See all 100 patients who’ve stopped taking Tecfidera

Duration

Currently taking Tecfidera

Duration Patients
0-1 month 1
1-3 months 2
3-6 months 8
6 months-1 year 23
1-2 years 47
2 years or more 99

Stopped taking Tecfidera

Duration Patients
0-1 month 16
1-3 months 17
3-6 months 14
6 months-1 year 22
1-2 years 21
2 years or more 9
1
Adherence
Adherence Evaluations
Always 353
Usually 65
Sometimes 5
Never taken as prescribed 13
Burden
Burden Evaluations
Very hard to take 10
Somewhat hard to take 30
A little hard to take 62
Not at all hard to take 334
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 3
$50-99 15
$25-49 38
< $25 225
Not specified 142

What people switch to and from

Patients started taking Tecfidera after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 45
Interferon beta-1a IM Injection (Avonex) 26
Interferon beta-1a SubQ injection (Rebif) 24
Interferon beta-1b SubQ Injection (Betaseron) 15
Natalizumab (Tysabri) 15

Show all 14 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:

Treatment Patients
Glatiramer acetate (Copaxone) 16
Teriflunomide (Aubagio) 14
Natalizumab (Tysabri) 12
Fingolimod (Gilenya) 4
Peginterferon beta-1a (Plegridy) 4

Show all 13 treatments patients report switching to

Last updated:

21 patient evaluations for Tecfidera

275 members have decided to share their profiles only with other members of PatientsLikeMe.

nsingle1
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nsingle1
Sex: F
Data Quality: 3 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: none
Speech: none
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See nsingle1's full Tecfidera history

Jul 28, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 1 helpful mark
grllongoria
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grllongoria
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: None
Cognition: none
Vision: none
Speech: none
Swallowing: none
Upper limb: none
Walking: severe
I am: g
I have:
MS

See grllongoria's full Tecfidera history

Feb 18, 2016 (Started Apr 30, 2013)

  • Effectiveness
    Slight (for Multiple Sclerosis)
  • side effects
    Mild (Flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: Past 2 MRI's have shown new lesions. This last MRI showed 1 new active lesion which caused a relapse was treated with steroids. Took a long while to get back to my normal.
Cost: < $25 monthly

Jun 19, 2013 (Started Apr 30, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • side effects
    Mild (Flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: I have felt 2 heavy legs numb, lifeless limbs right one dragged tripping me a lot for years. Another was a very painful area on my right thigh my granddaughters could not sit on my lap it was a burning sensation constantly. Nothing helped it. Three weeks into Tecfidera my legs feel lighter not as numb and no dragging. Feet and toes also more movement. Painful area totally gone. Walking also improved. Started week 7 June 18 and continue to have the flushing and itchy skin about once a day but this is very tolerable. Try hard to take this with food

  • 1 helpful mark
jmartell
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jmartell
Sex: F
Data Quality: 3 stars
Relapse: Moderate
Sensation: Moderate
Overall: Mild
Cognition: none
Vision: moderate
Speech: mild
Swallowing: none
Upper limb: mild
Walking: mild
I am: vg
I have:
MS

See jmartell's full Tecfidera history

Feb 15, 2016 (Started Dec 15, 2015)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    Severe (Flushing, Constant Flushing)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 120 mg Twice daily

  • 0 helpful marks
Last updated:
Showing 3 of 21 patient evaluations for Tecfidera