What is Tecfidera?

Category: Prescription Drugs

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Generic name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple Sclerosis 493 450
Drug ineffective 5 3
Allergic reaction 2 4
Vitamin B12 deficiency 2 4
Arthritis pain 1 0
Brain Atrophy Cerebrum 1 0

Show all 17 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 60
Moderate 69
Mild 203
None 120

Commonly reported side effects and conditions associated with Tecfidera

Side effect Patients
Flushing 95
Facial flushing 39
Diarrhea 36
Stomach pain 24
Nausea 20
Stomach upset 16

Show all 173 reported side effects

Dosages

Based on patients currently taking Tecfidera

Dosage Patients
240 mg twice daily 47
480 mg daily 25
120 mg twice daily 16
240 mg daily 16
120 mg daily 8
2 capsule(s) daily 7
2 capsule(s) twice daily 6
1 capsule(s) twice daily 4
1 tablet(s) twice daily 4
2 tablet(s) daily 4

See all 38 dosages

Why patients stopped taking Tecfidera

Multiple reasons could be selected

Reason Patients
Side effects too severe 64
Doctor's advice 35
Did not seem to work 24
Other 13
Course of treatment ended 2
Personal research 1
See all 104 patients who’ve stopped taking Tecfidera

Duration

Currently taking Tecfidera

Duration Patients
Less than 1 month 1
1 - 6 months 9
6 months - 1 year 17
1 - 2 years 49
2 - 5 years 99
5 - 10 years 1

Stopped taking Tecfidera

Duration Patients
Less than 1 month 17
1 - 6 months 31
6 months - 1 year 22
1 - 2 years 22
2 - 5 years 11
Adherence
Adherence Evaluations
Always 368
Usually 66
Sometimes 5
Never taken as prescribed 13
Burden
Burden Evaluations
Very hard to take 10
Somewhat hard to take 30
A little hard to take 65
Not at all hard to take 347
Cost per month
Cost per month Evaluations
$200+ 15
$100-199 3
$50-99 18
$25-49 39
< $25 231
Not specified 146

What people switch to and from

Patients started taking Tecfidera after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 48
Interferon beta-1a IM Injection (Avonex) 27
Interferon beta-1a SubQ injection (Rebif) 24
Interferon beta-1b SubQ Injection (Betaseron) 16
Natalizumab (Tysabri) 15

Show all 13 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:

Treatment Patients
Glatiramer acetate (Copaxone) 16
Teriflunomide (Aubagio) 14
Natalizumab (Tysabri) 12
Fingolimod (Gilenya) 4
Interferon beta-1a SubQ injection (Rebif) 4

Show all 13 treatments patients report switching to

Last updated:

21 patient evaluations for Tecfidera

282 members have decided to share their profiles only with other members of PatientsLikeMe.

1955chevy
27671 thumb
1955chevy
Sex: M
Data Quality: 3 stars
Sensation: None
Overall: None
Cognition: none
Vision: none
Speech: none
Swallowing: none
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See 1955chevy's full Tecfidera history

Sep 1, 2016 (Started Nov 10, 2015)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: Almost a year now and no lingering side effects.
Cost: < $25 monthly

Nov 24, 2015 (Started Nov 10, 2015)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    Mild (Facial flushing, Stomach upset)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: Eat something before taking the morning dose. I take the night dose right before bed. The stomach and flushing issues seem to be fading away now after entering the third week. Great to be away from the injections as I was having site issues after 17 years. Although in secondary progressive, Doc agreed with the decision the switch. Biogen is waving the $75 co-pay for me.
Cost: < $25 monthly

  • 0 helpful marks
nsingle1
62264 thumb
nsingle1
Sex: F
Data Quality: 3 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: none
Speech: none
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See nsingle1's full Tecfidera history

Jul 28, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • Side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 1 helpful mark
grllongoria
59441 thumb
grllongoria
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: None
Cognition: none
Vision: none
Speech: none
Swallowing: none
Upper limb: none
Walking: severe
I am: g
I have:
MS

See grllongoria's full Tecfidera history

Feb 18, 2016 (Started Apr 30, 2013)

  • Effectiveness
    Slight (for Multiple Sclerosis)
  • Side effects
    Mild (Flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: Past 2 MRI's have shown new lesions. This last MRI showed 1 new active lesion which caused a relapse was treated with steroids. Took a long while to get back to my normal.
Cost: < $25 monthly

Jun 19, 2013 (Started Apr 30, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • Side effects
    Mild (Flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Advice & Tips: I have felt 2 heavy legs numb, lifeless limbs right one dragged tripping me a lot for years. Another was a very painful area on my right thigh my granddaughters could not sit on my lap it was a burning sensation constantly. Nothing helped it. Three weeks into Tecfidera my legs feel lighter not as numb and no dragging. Feet and toes also more movement. Painful area totally gone. Walking also improved. Started week 7 June 18 and continue to have the flushing and itchy skin about once a day but this is very tolerable. Try hard to take this with food

  • 1 helpful mark
Last updated:
Showing 3 of 21 patient evaluations for Tecfidera