What is Tecfidera?

Category: Prescription Drugs

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Generic name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 569 545
Allergic reaction 2 4
Psoriasis 2 2
Arthritis pain 1 0
Brain atrophy cerebrum 1 0

Show all 13 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 74
Moderate 87
Mild 246
None 141

Commonly reported side effects and conditions associated with Tecfidera

Side effect Patients
Flushing 118
Facial flushing 42
Diarrhea 39
Nausea 29
Stomach pain 29
Upset stomach 16

Show all 188 reported side effects

Dosages

Based on patients currently taking Tecfidera

Dosage Patients
240 mg twice daily 61
480 mg daily 21
120 mg twice daily 12
240 mg daily 12
120 mg daily 9
2 capsule(s) daily 7
1 capsule(s) twice daily 4
2 tablet(s) daily 3
2 capsule(s) twice daily 3
480 mg twice daily 3

See all 28 dosages

Why patients stopped taking Tecfidera

Multiple reasons could be selected

Reason Patients
Side effects too severe 86
Doctor's advice 48
Did not seem to work 35
Other 19
Course of treatment ended 3
Change in health plan coverage 2
Expense 2
Personal research 2
See all 148 patients who've stopped taking Tecfidera

Duration

Currently taking Tecfidera

Duration Patients
1 - 6 months 6
6 months - 1 year 12
1 - 2 years 28
2 - 5 years 113
5 - 10 years 3

Stopped taking Tecfidera

Duration Patients
Less than 1 month 22
1 - 6 months 39
6 months - 1 year 28
1 - 2 years 30
2 - 5 years 28
Adherence
Adherence Evaluations
Always 439
Usually 82
Sometimes 8
Never taken as prescribed 19
Burden
Burden Evaluations
Very hard to take 14
Somewhat hard to take 36
A little hard to take 77
Not at all hard to take 421
Cost per month
Cost per month Evaluations
$200+ 18
$100-199 3
$50-99 16
$25-49 45
< $25 289
Not specified 177

What people switch to and from

Patients started taking Tecfidera after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 71
Interferon beta-1a IM Injection (Avonex) 36
Interferon beta-1a SubQ injection (Rebif) 33
Natalizumab (Tysabri) 26
Interferon beta-1b SubQ Injection (Betaseron) 23

Show all 15 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:

Treatment Patients
Glatiramer acetate (Copaxone) 22
Teriflunomide (Aubagio) 21
Natalizumab (Tysabri) 18
Fingolimod (Gilenya) 8
Rituximab (Rituxan) 7

Show all 15 treatments patients report switching to

Last updated:

26 patient evaluations for Tecfidera

Aug 2, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 16, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 28, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 2 helpful marks

Jul 29, 2017 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: i've reduced my dosage to 240 mg(half), because having only a 300 cell margin is simply too small.
Cost: < $25 monthly

Sep 30, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: my jc virus level is just slightly greater, so I'll continue with it.
Cost: < $25 monthly

Jan 25, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I feel my JC virus titer level is high at 2.14, but there is presently no other drug with a safer side-effect profile, so I'm waiting for the next approved MS medication to switch to:-(
Cost: < $25 monthly

Feb 26, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: Tuesday's MRI is clear (no new or active lesions), so will continue with this medication.
Cost: < $25 monthly

Jan 14, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I must eat a meal with meat or I'll throw-up.
Cost: < $25 monthly

  • 0 helpful marks

Apr 21, 2017 (Started Jul 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: It's still working'
Cost: < $25 monthly

Jul 15, 2013 (Started Jul 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: If nothing else was working for you I would recommend that you talk to your Dr. about it.
Cost: $200+ monthly

  • 1 helpful mark
Last updated:
Showing 3 of 26 patient evaluations for Tecfidera