What is Tecfidera?

Category: Prescription Drugs

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Generic name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple Sclerosis 537 505
Drug ineffective 5 4
Allergic reaction 2 4
Psoriasis 2 2
Arthritis pain 1 0
Brain Atrophy Cerebrum 1 0

Show all 17 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 68
Moderate 81
Mild 230
None 129

Commonly reported side effects and conditions associated with Tecfidera

Side effect Patients
Flushing 107
Facial flushing 40
Diarrhea 38
Nausea 28
Stomach pain 26
Upset stomach 16

Show all 185 reported side effects

Dosages

Based on patients currently taking Tecfidera

Dosage Patients
240 mg twice daily 57
120 mg twice daily 21
480 mg daily 19
240 mg daily 16
2 capsule(s) daily 9
120 mg daily 6
480 mg twice daily 5
1 capsule(s) twice daily 4
2 tablet(s) daily 4
2 capsule(s) twice daily 3

See all 29 dosages

Why patients stopped taking Tecfidera

Multiple reasons could be selected

Reason Patients
Side effects too severe 77
Doctor's advice 41
Did not seem to work 31
Other 16
Course of treatment ended 3
Change in health plan coverage 2
Expense 2
Personal research 1
See all 128 patients who’ve stopped taking Tecfidera

Duration

Currently taking Tecfidera

Duration Patients
Less than 1 month 1
1 - 6 months 14
6 months - 1 year 11
1 - 2 years 32
2 - 5 years 110
5 - 10 years 1

Stopped taking Tecfidera

Duration Patients
Less than 1 month 21
1 - 6 months 35
6 months - 1 year 24
1 - 2 years 30
2 - 5 years 17
Adherence
Adherence Evaluations
Always 409
Usually 75
Sometimes 7
Never taken as prescribed 17
Burden
Burden Evaluations
Very hard to take 13
Somewhat hard to take 33
A little hard to take 71
Not at all hard to take 391
Cost per month
Cost per month Evaluations
$200+ 18
$100-199 3
$50-99 16
$25-49 44
< $25 262
Not specified 165

What people switch to and from

Patients started taking Tecfidera after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 61
Interferon beta-1a IM Injection (Avonex) 33
Interferon beta-1a SubQ injection (Rebif) 32
Interferon beta-1b SubQ Injection (Betaseron) 19
Natalizumab (Tysabri) 19

Show all 14 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:

Treatment Patients
Teriflunomide (Aubagio) 20
Glatiramer acetate (Copaxone) 18
Natalizumab (Tysabri) 16
Fingolimod (Gilenya) 6
Interferon beta-1a SubQ injection (Rebif) 5

Show all 14 treatments patients report switching to

Last updated:

24 patient evaluations for Tecfidera

311 members have decided to share their profiles only with other members of PatientsLikeMe.

nsingle1
62264 thumb
nsingle1
Sex: F
Data Quality: 3 stars
Sensation: Mild
Overall: Mild
Cognition: mild
Vision: moderate
Speech: mild
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See nsingle1's full Tecfidera history

Mar 16, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 28, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • Side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 1 helpful mark
fiftynwell
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fiftynwell
Sex: F
Data Quality: 0 stars
Sensation: Mild
Overall: None
Cognition: moderate
Vision: none
Speech: mild
Swallowing: mild
Upper limb: none
Walking: mild
I have:
MS

See fiftynwell's full Tecfidera history

Mar 8, 2017 (Started Jul 15, 2015)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side effects
    Mild (Flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks
1955chevy
27671 thumb
1955chevy
Sex: M
Data Quality: 3 stars
Sensation: None
Overall: None
Cognition: none
Vision: none
Speech: none
Swallowing: none
Upper limb: mild
Walking: moderate
I am: g
I have:
MS

See 1955chevy's full Tecfidera history

Dec 8, 2016 (Started Nov 10, 2015)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • Side effects
    Mild (Facial flushing, Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: One pill twice a day, no problem. Occasional minor face flushing, maybe once or twice a month.
Cost: < $25 monthly

Sep 1, 2016 (Started Nov 10, 2015)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: Almost a year now and no lingering side effects.
Cost: < $25 monthly

Nov 24, 2015 (Started Nov 10, 2015)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • Side effects
    Mild (Facial flushing, Upset stomach)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 240 mg Twice daily
Advice & Tips: Eat something before taking the morning dose. I take the night dose right before bed. The stomach and flushing issues seem to be fading away now after entering the third week. Great to be away from the injections as I was having site issues after 17 years. Although in secondary progressive, Doc agreed with the decision the switch. Biogen is waving the $75 co-pay for me.
Cost: < $25 monthly

  • 1 helpful mark
Last updated:
Showing 3 of 24 patient evaluations for Tecfidera