What is Tecfidera?

Category: Prescription Drugs

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Generic name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness

Purpose
Patients
Patients with evaluations
Perceived effectiveness
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0
Perceived effectiveness
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0
Perceived effectiveness
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Perceived effectiveness
Purpose
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0
Perceived effectiveness
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0
Perceived effectiveness

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 41
Moderate 36
Mild 107
None 62

Commonly reported side effects and conditions associated with Tecfidera

Side effect Patients
Flushing 79
Facial flushing 36
Diarrhea 32
Nausea 20
Stomach pain 17
Stomach upset 16

Show all 168 reported side effects

Dosages

Based on patients currently taking Tecfidera

Dosage Patients
240 mg twice daily 55
480 mg daily 31
120 mg twice daily 22
240 mg daily 18
120 mg daily 13
2 capsule(s) daily 10
1 capsule(s) twice daily 8
2 capsule(s) twice daily 7
2 tablet(s) daily 5
2 other daily 3

See all 39 dosages

Why patients stopped taking Tecfidera

Multiple reasons could be selected

Reason Patients
Side effects too severe 60
Doctor's advice 30
Did not seem to work 20
Other 9
Course of treatment ended 1
Personal research 1
See all 90 patients who’ve stopped taking Tecfidera

Duration

Currently taking Tecfidera

Duration Patients
0-1 month 2
1-3 months 4
3-6 months 14
6 months-1 year 29
1-2 years 64
2 years or more 99

Stopped taking Tecfidera

Duration Patients
0-1 month 16
1-3 months 16
3-6 months 12
6 months-1 year 21
1-2 years 18
2 years or more 6
1

Adherence


Always
Patients
196
80%
Usually
Patients
39
16%
Sometimes
Patients
4
2%
Never taken as prescribed
Patients
7
3%

Burden


Very hard to take
Patients
7
3%
Somewhat hard to take
Patients
16
7%
A little hard to take
Patients
33
13%
Not at all hard to take
Patients
190
77%

Cost per month


Cost per month
$200+
Patients
10
4%
Cost per month
$100-199
Patients
3
1%
Cost per month
$50-99
Patients
9
4%
Cost per month
$25-49
Patients
23
9%
Cost per month
< $25
Patients
117
48%
Cost per month
Not specified
Patients
84
34%

What people switch to and from

Patients started taking Tecfidera after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 35
Interferon beta-1a IM Injection (Avonex) 23
Interferon beta-1a SubQ injection (Rebif) 22
Interferon beta-1b SubQ Injection (Betaseron) 12
Natalizumab (Tysabri) 12

Show all 12 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:

Treatment Patients
Glatiramer acetate (Copaxone) 14
Natalizumab (Tysabri) 11
Teriflunomide (Aubagio) 11
Peginterferon beta-1a (Plegridy) 4
Fingolimod (Gilenya) 3

Show all 13 treatments patients report switching to

Last updated:

20 patient evaluations for Tecfidera

nsingle1
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nsingle1
Sex: F
Data Quality: 3 stars
Sensation: Mild
Overall: Mild
Cognition: mild
Vision: mild
Speech: none
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: g
I have:
MS

See nsingle1's full Tecfidera history

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • side effects
    Mild (Stomach pain, Flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can’t tell (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 0 helpful marks
thjuland
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thjuland
Sex: M
Data Quality: 3 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: none
Speech: none
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: vg
I have:
MS

See thjuland's full Tecfidera history

Jan 25, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I feel my JC virus titer level is high at 2.14, but there is presently no other drug with a safer side-effect profile, so I'm waiting for the next approved MS medication to switch to:-(
Cost: < $25 monthly

Feb 26, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: Tuesday's MRI is clear (no new or active lesions), so will continue with this medication.
Cost: < $25 monthly

Jan 14, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I must eat a meal with meat or I'll throw-up.
Cost: < $25 monthly

  • 0 helpful marks
amwhalen
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amwhalen
Sex: F
Data Quality: 2 stars
Sensation: Mild
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I have:
MS

See amwhalen's full Tecfidera history

Jan 20, 2016 (Started Feb 10, 2015)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 tablet(s) Twice daily

  • 0 helpful marks
Last updated:
Showing 3 of 20 patient evaluations for Tecfidera