What is Tecfidera?

Category: Prescription Drugs

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Generic Name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness

Purpose
Patients
Patients with evaluations
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects of Tecfidera

Severe
38
Moderate
35
Mild
101
None
58

Commonly reported side effects, conditions, and hospitalizations associated with Tecfidera

Patients
67
Patients
36
Patients
30
Patients
20
Patients
17
Patients
14

Show all 162 reported side effects

Dosages

Most common dosages (by patients currently taking Tecfidera)
Dosage
240 mg daily
Patients
82
Dosage
240 mg twice daily
Patients
82
Dosage
480 mg daily
Patients
82
Dosage
2 capsule(s) daily
Patients
40
Dosage
120 mg twice daily
Patients
39
Dosage
120 mg daily
Patients
31
Dosage
1 capsule(s) twice daily
Patients
14
Dosage
2 tablet(s) daily
Patients
12
Dosage
2 capsule(s) twice daily
Patients
8
Dosage
250 mg twice daily
Patients
6

Dosages based on patients currently taking Tecfidera.

Why Patients Stopped Taking Tecfidera (multiple reasons could be selected)
Reason
Side effects too severe
Patients
57
Reason
Doctor's advice
Patients
28
Reason
Did not seem to work
Patients
20
Reason
Other
Patients
9
Reason
Personal research
Patients
1
Reason
Expense
Patients
1
Reason
Course of treatment ended
Patients
1
Reason
Not indicated
Patients
1
See all 89 patients who’ve stopped taking Tecfidera

Duration

Currently Taking Tecfidera
Duration
Patients
Duration
0-1 month
Patients
1
Duration
1-3 months
Patients
5
Duration
3-6 months
Patients
14
Duration
6 months-1 year
Patients
28
Duration
1-2 years
Patients
67
Duration
2 years or more
Patients
110
Stopped Taking Tecfidera
Duration
Patients
Duration
0-1 month
Patients
13
Duration
1-3 months
Patients
11
Duration
3-6 months
Patients
12
Duration
6 months-1 year
Patients
20
Duration
1-2 years
Patients
18
Duration
2 years or more
Patients
5

Adherence


Always
Patients
184
79%
Usually
Patients
38
16%
Sometimes
Patients
4
2%
Never taken as prescribed
Patients
6
3%

Burden


Very hard to take
Patients
6
3%
Somewhat hard to take
Patients
16
7%
A little hard to take
Patients
33
14%
Not at all hard to take
Patients
177
76%

Cost per month


Cost per month
$200+
Patients
10
4%
Cost per month
$100-199
Patients
1
0%
Cost per month
$50-99
Patients
9
4%
Cost per month
$25-49
Patients
23
10%
Cost per month
< $25
Patients
110
47%
Cost per month
Not specified
Patients
79
34%

What people switch to and from

Patients started taking Tecfidera after stopping:
Treatment name(s)
Glatiramer acetate (Copaxone)
Patients
32
Treatment name(s)
Interferon beta-1a SubQ injection (Rebif, Rebif Rebidose)
Patients
25
Treatment name(s)
Interferon beta-1a IM Injection (Avonex, Avonex Prefilled Syringe, Avonex Pen)
Patients
18
Treatment name(s)
Natalizumab (Tysabri, Antegren)
Patients
11
Treatment name(s)
Interferon beta-1b SubQ Injection (Betaseron, Betaferon, Extavia…)
Patients
10

See all 13 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:
Treatment name(s)
Glatiramer acetate (Copaxone)
Patients
13
Treatment name(s)
Natalizumab (Tysabri, Antegren)
Patients
12
Treatment name(s)
Teriflunomide (Aubagio)
Patients
11
Treatment name(s)
Fingolimod (Gilenya)
Patients
5
Treatment name(s)
Peginterferon beta-1a (Plegridy)
Patients
4

See all 10 treatments patients report switching to

Last updated:

20 patient evaluations for Tecfidera

thjuland
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thjuland
Sex: M
Data Quality: 3 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: none
Swallowing: mild
Upper limb: moderate
Walking: moderate
I am: vg
I have:
MS

See thjuland's full Tecfidera history

Jan 25, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side Effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I feel my JC virus titer level is high at 2.14, but there is presently no other drug with a safer side-effect profile, so I'm waiting for the next approved MS medication to switch to:-(
Cost: < $25 monthly

Feb 26, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side Effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: Tuesday's MRI is clear (no new or active lesions), so will continue with this medication.
Cost: < $25 monthly

Jan 14, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side Effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I must eat a meal with meat or I'll throw-up.
Cost: < $25 monthly

  • 0 helpful marks
amwhalen
4100 thumb
amwhalen
Sex: F
Data Quality: 3 stars
Sensation: Mild
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I have:
MS

See amwhalen's full Tecfidera history

Jan 20, 2016 (Started Feb 10, 2015)

  • Effectiveness
    Moderate (for Multiple Sclerosis)
  • Side Effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 tablet(s) Twice daily

  • 0 helpful marks
Xicana
46552 thumb
Xicana
Sex: F
Data Quality: 2 stars
Sensation: Mild
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See Xicana's full Tecfidera history

Jan 19, 2016 (Started Oct 24, 2013)

  • Effectiveness
    Major (for Multiple Sclerosis)
  • Side Effects
    Moderate (Itchy skin)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 tablet(s) Daily
Advice & Tips: eat
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 20 patient evaluations for Tecfidera