What is Tecfidera?

Category: Prescription Drugs

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Generic Name: Dimethyl fumarate

Tecfidera (dimethyl fumarate, BG-12) is used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Purpose
Patients
Patients with evaluations
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness
Patients
Patients with evaluations
0
Perceived effectiveness

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects of Tecfidera

Severe
28
Moderate
28
Mild
86
None
47

Commonly reported side effects, conditions, and hospitalizations associated with Tecfidera

Patients
56
Patients
34
Patients
22
Patients
19
Patients
13
Patients
11

Show all 148 reported side effects

Dosages

Most common dosages (by patients currently taking Tecfidera)
Dosage
480 mg daily
Patients
85
Dosage
240 mg daily
Patients
84
Dosage
240 mg twice daily
Patients
50
Dosage
2 capsule(s) daily
Patients
41
Dosage
120 mg daily
Patients
32
Dosage
120 mg twice daily
Patients
26
Dosage
2 tablet(s) daily
Patients
12
Dosage
1 capsule(s) twice daily
Patients
10
Dosage
1 capsule(s) daily
Patients
5
Dosage
2 capsule(s) twice daily
Patients
5

Dosages based on patients currently taking Tecfidera.

Why Patients Stopped Taking Tecfidera (multiple reasons could be selected)
Reason
Side effects too severe
Patients
41
Reason
Doctor's advice
Patients
19
Reason
Did not seem to work
Patients
12
Reason
Other
Patients
4
Reason
Expense
Patients
1
Reason
Course of treatment ended
Patients
1
Reason
Not indicated
Patients
1
See all 61 patients who’ve stopped taking Tecfidera

Duration

Currently Taking Tecfidera
Duration
Patients
Duration
0-1 month
Patients
2
Duration
1-3 months
Patients
10
Duration
3-6 months
Patients
9
Duration
6 months-1 year
Patients
33
Duration
1-2 years
Patients
81
Duration
2 years or more
Patients
35
Stopped Taking Tecfidera
Duration
Patients
Duration
0-1 month
Patients
9
Duration
1-3 months
Patients
10
Duration
3-6 months
Patients
9
Duration
6 months-1 year
Patients
14
Duration
1-2 years
Patients
12
Duration
2 years or more
Patients
0

Adherence


Always
Patients
156
83%
Usually
Patients
26
14%
Sometimes
Patients
3
2%
Never
Patients
4
2%

Burden


Very
Patients
4
2%
Somewhat
Patients
10
5%
A little
Patients
32
17%
Not at all
Patients
143
76%

Cost per month


Cost per month
$200+
Patients
62
49%
Cost per month
$100-199
Patients
9
7%
Cost per month
$50-99
Patients
1
1%
Cost per month
$25-49
Patients
8
6%
Cost per month
< $25
Patients
19
15%
Cost per month
Not specified
Patients
90
71%

What people switch to and from

Patients started taking Tecfidera after stopping:
Treatment name(s)
Glatiramer acetate (Copaxone)
Patients
11
Treatment name(s)
Interferon beta-1a IM Injection (Avonex, Avonex Prefilled Syringe, Avonex Pen)
Patients
9
Treatment name(s)
Interferon beta-1a SubQ injection (Rebif, Rebif Rebidose)
Patients
8
Treatment name(s)
Natalizumab (Tysabri, Antegren)
Patients
6
Treatment name(s)
Fingolimod (Gilenya, MS Phase 3 Fingolimod TRANSFORMS, MS Phase 3 Study Fingolimod FREEDOMS II…)
Patients
5

See all 11 treatments patients report switching from

Patients stopped taking Tecfidera and switched to:
Treatment name(s)
Glatiramer acetate (Copaxone)
Patients
6
Treatment name(s)
Natalizumab (Tysabri, Antegren)
Patients
5
Treatment name(s)
Teriflunomide (Aubagio)
Patients
5
Treatment name(s)
Peginterferon beta-1a (Plegridy)
Patients
3
Treatment name(s)
Fingolimod (Gilenya, MS Phase 3 Fingolimod TRANSFORMS, MS Phase 3 Study Fingolimod FREEDOMS II…)
Patients
2

See all 6 treatments patients report switching to

Last updated:

18 patient evaluations for Tecfidera

UfieDufie
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UfieDufie
Sex: F
Data Quality: 3 stars
Relapse: Moderate
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: vb
I have:
MS

See UfieDufie's full Tecfidera history

May 11, 2015 (Started Sep 20, 2014)

  • Perceived effectiveness for Multiple Sclerosis: Moderate
  • Side Effects: Severe
  • Adherence: Usually
  • Burden: Not at all
Dosage: 2 capsule(s) Twice daily
Advice & Tips: Always take with food. And don't miss doses, I've by accident missed days. When starting to take it again the flushing was so bad I was red as a lobster for hours.

  • 0 helpful marks
thjuland
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thjuland
Sex: M
Data Quality: 3 stars
Sensation: Mild
Overall: Mild
Cognition: moderate
Vision: none
Speech: mild
Swallowing: moderate
Upper limb: mild
Walking: moderate
I am: vg
I have:
MS

See thjuland's full Tecfidera history

Feb 26, 2015 (Started Nov 05, 2013)

  • Perceived effectiveness for Multiple Sclerosis: Major
  • Side Effects: None
  • Adherence: Always
  • Burden: Not at all
Dosage: 480 mg Daily
Advice & Tips: Tuesday's MRI is clear (no new or active lesions), so will continue with this medication.
Cost: Not specified monthly

Jan 14, 2015 (Started Nov 05, 2013)

  • Perceived effectiveness for Multiple Sclerosis: Major
  • Side Effects: None
  • Adherence: Always
  • Burden: Not at all
Dosage: 480 mg Daily
Advice & Tips: I must eat a meal with meat or I'll throw-up.
Cost: Not specified monthly

  • 0 helpful marks
moogie16
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moogie16
Sex: F
Data Quality: 2 stars
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: moderate
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: b
I have:
MS

See moogie16's full Tecfidera history

Dec 29, 2014 (Started Nov 30, 2014)

  • Perceived effectiveness for Multiple Sclerosis: Can’t tell
  • Side Effects: Moderate
  • Adherence: Always
  • Burden: Not at all
Dosage: 250 mg Twice daily
Advice & Tips: one baby aspirin before taking tablet
Cost: Not specified monthly

  • 1 helpful mark
Last updated:
Showing 3 of 18 patient evaluations for Tecfidera