What is Dimethyl fumarate?

Category: Prescription Drugs

Most popular types: Tecfidera

false

Dimethyl fumarate is primarily used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 1,001 863
Participate in clinical trial 10 11
Allergic reaction 2 4
Psoriasis 2 2
Arthritis pain 1 0

Show all 16 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
137
Moderate
157
Mild
361
None
219

Commonly reported side effects and conditions associated with Dimethyl fumarate

Side effect Patients
Flushing 191
Facial flushing 60
Diarrhea 54
Nausea 53
Stomach pain 43
Upset stomach 28

Show all 248 reported side effects

Dosages

Based on patients currently taking Dimethyl fumarate

Dosage Patients
240 mg twice daily 101
120 mg twice daily 27
480 mg daily 27
240 mg daily 23
120 mg daily 15
480 mg twice daily 9
2 capsule(s) daily 8
1 capsule(s) twice daily 6
1 tablet(s) twice daily 5
2 tablet(s) daily 4

See all 38 dosages

Why patients stopped taking Dimethyl fumarate

Multiple reasons could be selected

Reason Patients
Side effects too severe 153
Doctor's advice 87
Did not seem to work 72
Other 41
Course of treatment ended 10
Personal research 9
Change in health plan coverage 5
Expense 4
See all 289 patients who've stopped taking Dimethyl fumarate

Duration

Currently taking Dimethyl fumarate

Duration Patients
1 - 6 months 11
6 months - 1 year 7
1 - 2 years 39
2 - 5 years 204
5 - 10 years 8

Stopped taking Dimethyl fumarate

Duration Patients
Less than 1 month 56
1 - 6 months 71
6 months - 1 year 56
1 - 2 years 58
2 - 5 years 47
5 - 10 years 1
10 years or more 1
Adherence
Adherence Evaluations
Always 693
Usually 122
Sometimes 14
Never taken as prescribed 45
Burden
Burden Evaluations
Very hard to take 43
Somewhat hard to take 60
A little hard to take 136
Not at all hard to take 635
Cost per month
Cost per month Evaluations
$200+ 29
$100-199 7
$50-99 27
$25-49 55
< $25 436
Not specified 320

What people switch to and from

Patients started taking Dimethyl fumarate after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 118
Interferon beta-1a IM Injection (Avonex) 57
Interferon beta-1a SubQ injection (Rebif) 53
Natalizumab (Tysabri) 49
Fingolimod (Gilenya) 29

Show all 20 treatments patients report switching from

Patients stopped taking Dimethyl fumarate and switched to:

Treatment Patients
Teriflunomide (Aubagio) 41
Glatiramer acetate (Copaxone) 37
Natalizumab (Tysabri) 30
Fingolimod (Gilenya) 25
Peginterferon beta-1a (Plegridy) 11

Show all 17 treatments patients report switching to

Last updated:

36 patient evaluations for Dimethyl fumarate

Dec 15, 2017 (Started May 16, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Advice & Tips: when I had been taking Tecfidera, I had taken a low-dose aspirin a few minutes before swallowing the capsule. The low-dose aspirin relieved the flushing feeling on my face and neck.
Cost: < $25 monthly

Sep 15, 2017 (Started May 16, 2013)

  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Cost: < $25 monthly

  • 1 helpful mark

Aug 2, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 16, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 28, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 2 helpful marks

Apr 21, 2017 (Started Jul 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: It's still working'
Cost: < $25 monthly

Jul 15, 2013 (Started Jul 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: If nothing else was working for you I would recommend that you talk to your Dr. about it.
Cost: $200+ monthly

  • 1 helpful mark
Last updated:
Showing 3 of 36 patient evaluations for Dimethyl fumarate