What is Dimethyl fumarate?

Category: Prescription Drugs

Most popular types: Tecfidera

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Dimethyl fumarate is primarily used for the treatment of relapsing remitting MS. It is an oral medication and is used to help reduce the number of relapses a patient experiences.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 995 866
Participate in clinical trial 10 11
Allergic reaction 2 4
Psoriasis 2 2
Arthritis pain 1 0

Show all 14 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
136
Moderate
159
Mild
362
None
219

Commonly reported side effects and conditions associated with Dimethyl fumarate

Side effect Patients
Flushing 190
Facial flushing 60
Diarrhea 54
Nausea 53
Stomach pain 43
Upset stomach 28

Show all 249 reported side effects

Dosages

Based on patients currently taking Dimethyl fumarate

Dosage Patients
240 mg twice daily 102
120 mg twice daily 27
480 mg daily 27
240 mg daily 18
120 mg daily 17
480 mg twice daily 9
1 capsule(s) twice daily 8
2 capsule(s) daily 8
2 tablet(s) daily 4
2 capsule(s) twice daily 4

See all 43 dosages

Why patients stopped taking Dimethyl fumarate

Multiple reasons could be selected

Reason Patients
Side effects too severe 152
Doctor's advice 86
Did not seem to work 70
Other 39
Course of treatment ended 10
Personal research 9
Change in health plan coverage 5
Expense 4
See all 284 patients who've stopped taking Dimethyl fumarate

Duration

Currently taking Dimethyl fumarate

Duration Patients
Less than 1 month 2
1 - 6 months 7
6 months - 1 year 13
1 - 2 years 37
2 - 5 years 203
5 - 10 years 9

Stopped taking Dimethyl fumarate

Duration Patients
Less than 1 month 54
1 - 6 months 71
6 months - 1 year 56
1 - 2 years 56
2 - 5 years 46
5 - 10 years 1
10 years or more 1
Adherence
Adherence Evaluations
Always 696
Usually 122
Sometimes 14
Never taken as prescribed 44
Burden
Burden Evaluations
Very hard to take 43
Somewhat hard to take 60
A little hard to take 136
Not at all hard to take 637
Cost per month
Cost per month Evaluations
$200+ 29
$100-199 7
$50-99 27
$25-49 55
< $25 439
Not specified 319

What people switch to and from

Patients started taking Dimethyl fumarate after stopping:

Treatment Patients
Glatiramer acetate (Copaxone) 117
Interferon beta-1a IM Injection (Avonex) 57
Interferon beta-1a SubQ injection (Rebif) 54
Natalizumab (Tysabri) 49
Fingolimod (Gilenya) 29

Show all 20 treatments patients report switching from

Patients stopped taking Dimethyl fumarate and switched to:

Treatment Patients
Teriflunomide (Aubagio) 40
Glatiramer acetate (Copaxone) 37
Natalizumab (Tysabri) 29
Fingolimod (Gilenya) 25
Peginterferon beta-1a (Plegridy) 11

Show all 17 treatments patients report switching to

Last updated:

37 patient evaluations for Dimethyl fumarate

Dec 15, 2017 (Started May 16, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Advice & Tips: when I had been taking Tecfidera, I had taken a low-dose aspirin a few minutes before swallowing the capsule. The low-dose aspirin relieved the flushing feeling on my face and neck.
Cost: < $25 monthly

Sep 15, 2017 (Started May 16, 2013)

  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    Severe (increased indexes for PML.)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 240 mg Daily
Cost: < $25 monthly

  • 1 helpful mark

Aug 2, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 16, 2017 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 28, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Mar 10, 2016 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Dec 11, 2015 (Started Dec 23, 2013)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild (stomach pain, flushing)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Sep 27, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Cost: < $25 monthly

Jul 22, 2014 (Started Dec 23, 2013)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily

  • 2 helpful marks

Jul 29, 2017 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: i've reduced my dosage to 240 mg(half), because having only a 300 cell margin is simply too small.
Cost: < $25 monthly

Sep 30, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: my jc virus level is just slightly greater, so I'll continue with it.
Cost: < $25 monthly

Jan 25, 2016 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Moderate (JC virus present in blood test)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I feel my JC virus titer level is high at 2.14, but there is presently no other drug with a safer side-effect profile, so I'm waiting for the next approved MS medication to switch to:-(
Cost: < $25 monthly

Feb 26, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: Tuesday's MRI is clear (no new or active lesions), so will continue with this medication.
Cost: < $25 monthly

Jan 14, 2015 (Started Nov 05, 2013)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 480 mg Daily
Advice & Tips: I must eat a meal with meat or I'll throw-up.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 37 patient evaluations for Dimethyl fumarate