What is Lactulose?

Category: Prescription Drugs

Most popular types: Generlac Kristalose Duphalac Show all

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Lactulose is a laxative drug taken as an oral syrup and used to treat constipation. It is also used in the prevention and treatment of portal-systemic encephalopathy, a neuropsychiatric syndrome associated with liver disease.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Constipation 89 45
Irritable bowel syndrome 53 11
Bowel problems 24 14
Chronic constipation 4 4
General health 4 3

Show all 28 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 9
Moderate 11
Mild 9
None 46

Commonly reported side effects and conditions associated with Lactulose

Side effect Patients
Diarrhea 6
Abdominal cramps 3
Nausea 2
Abdominal bloating 1
Bowel incontinence 1
Dehydration 1

Show all 13 reported side effects

Dosages

Based on patients currently taking Lactulose

Dosage Patients
10 g/15ml twice daily 2
2 x 10 g/15 mL daily 2
30 x 10 g/15ml twice daily 2
10g/15mL as needed 2
2 tbs. daily 1
10 g/15 mL daily 1
10 g/15ml daily 1
10 mL daily 1
20 mL daily 1
2 x 10 g/15ml daily 1

See all 16 dosages

Why patients stopped taking Lactulose

Multiple reasons could be selected

Reason Patients
Did not seem to work 24
Other 18
Doctor's advice 15
Side effects too severe 10
Course of treatment ended 8
Personal research 3
Change in health plan coverage 2
Expense 2
See all 66 patients who've stopped taking Lactulose

Duration

Currently taking Lactulose

Duration Patients
6 months - 1 year 1
1 - 2 years 3
2 - 5 years 7
5 - 10 years 9

Stopped taking Lactulose

Duration Patients
Less than 1 month 16
1 - 6 months 13
6 months - 1 year 12
1 - 2 years 10
2 - 5 years 6
5 - 10 years 7
10 years or more 2
Adherence
Adherence Evaluations
Always 41
Usually 23
Sometimes 9
Never taken as prescribed 2
Burden
Burden Evaluations
Very hard to take 8
Somewhat hard to take 11
A little hard to take 16
Not at all hard to take 40
Cost per month
Cost per month Evaluations
$200+ 1
$100-199 0
$50-99 4
$25-49 7
< $25 38
Not specified 25

What people switch to and from

Patients started taking Lactulose after stopping:

Treatment Patients
Lubiprostone (Amitiza) 1
Naloxegol (Movantik) 1

Patients stopped taking Lactulose and switched to:

Treatment Patients
Polyethylene glycol 3350 with electrolytes (Colyte) 2
Lubiprostone (Amitiza) 1
Polyethylene Glycol 3350 (MiraLax) 1
Senna (Senokot) 1
Last updated:

14 patient evaluations for Lactulose

Apr 22, 2016 (Started Jan 15, 2016)

  • Effectiveness
    Major (for constipation)
  • Side effects
    Moderate (hearing loss in left ear)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: started 3 teaspoons / day, then started 3 tablespoons / day PCP recommendation ; 3 days later hearing loss ,started loud ringing in left ear ,checked web this could cause hearing loss ,stopped
Cost: $25-49 monthly

Apr 15, 2016 (Started Jan 15, 2016)

  • Effectiveness
    Major (for constipation)
  • Side effects
    Severe (hearing loss in left ear)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 10 g/15 mL Three times daily
Advice & Tips: hearing and vision deteration
Cost: $25-49 monthly

  • 0 helpful marks

Nov 18, 2014 (Started Oct 31, 2014)

  • Effectiveness
    Slight (for constipation)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 g/15 mL Twice daily
Advice & Tips: Gentle - maybe a little too gentle if on pain killers like Codine. Need to drink lots of water, but even then I didn't get much relief. I found it was best taken regularly with a Glycerol Suppository first thing in the morning. That broke the log jam after 7 days!

  • 0 helpful marks

Oct 6, 2014 (Started Sep 15, 2014)

  • Effectiveness
    Moderate (for constipation)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 tbs. Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 14 patient evaluations for Lactulose