What is Orphenadrine?

Category: Prescription Drugs

Most popular types: Norflex Orphenadrine ER Disipal Show all

false

See also: Orphenadrine-aspirin-caffeine

Orphenadrine is an anti-Parkinson's and skeletal muscle relaxant. It is used in the treatment of muscle spasm and tremors associated with musculoskeletal conditions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Fibromyalgia 27 7
Muscle spasms 25 9
Stiffness/spasticity 20 14
Muscle pain 3 0
Muscle tension 3 2
Neck pain 3 3

Show all 41 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
5
Moderate
7
Mild
12
None
11

Commonly reported side effects and conditions associated with Orphenadrine

Side effect Patients
Dry mouth 3
Drowsiness 2
Sleepiness 2
Awakened by talking in sleep 1
Bowel incontinence 1
Chronic constipation 1

Show all 24 reported side effects

Dosages

Based on patients currently taking Orphenadrine

Dosage Patients
100 mg twice daily 3
100mg as needed 2
50 mg daily 1
100 mg daily 1

Why patients stopped taking Orphenadrine

Multiple reasons could be selected

Reason Patients
Doctor's advice 8
Did not seem to work 6
Side effects too severe 6
Other 4
Course of treatment ended 3
Personal research 2
Change in health plan coverage 1
See all 23 patients who've stopped taking Orphenadrine

Duration

Currently taking Orphenadrine

Duration Patients
1 - 6 months 1
6 months - 1 year 2
2 - 5 years 3
10 years or more 1

Stopped taking Orphenadrine

Duration Patients
Less than 1 month 5
1 - 6 months 8
6 months - 1 year 3
1 - 2 years 1
2 - 5 years 3
5 - 10 years 3
Adherence
Adherence Evaluations
Always 24
Usually 5
Sometimes 3
Never taken as prescribed 3
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 3
A little hard to take 5
Not at all hard to take 27
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 0
$50-99 0
$25-49 1
< $25 17
Not specified 17

What people switch to and from

Patients started taking Orphenadrine after stopping:

Treatment Patients
Baclofen (Mylan-Baclofen) 1
Tizanidine (Zanaflex) 1
Verapamil (Verapamil ER) 1

Patients stopped taking Orphenadrine and switched to:

Treatment Patients
Baclofen (Mylan-Baclofen) 1
Last updated:

3 patient evaluations for Orphenadrine

Jul 6, 2011 (Started Nov 04, 2007)

  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Advice & Tips: Affects short-term memory /retention
Cost: < $25 monthly
Side effects: memory problems, loss of short term memory, forgetting words

May 24, 2011 (Started Nov 04, 2007)

  • Effectiveness
    Major (for stiffness/spasticity)
  • Side effects
    Moderate (forgetting words, loss of short term memory, memory problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Unfortunately after many years relatively free of stiffness, tremor & associated pain over the last 18 months I became increasingly forgetful & confused.
Cost: < $25 monthly
Side effects: memory problems, loss of short term memory, forgetting words

May 12, 2011 (Started Nov 04, 2007)

  • Effectiveness
    Major (for stiffness/spasticity)
  • Side effects
    Severe (forgetting words, loss of short term memory, memory problems)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: For many years (4+) this helped reduce tremor & associated pain, helped balance & was generally beneficial BUT the cognitive side effects, similar to dementia, were intolerable.
Cost: < $25 monthly
Side effects: memory problems, loss of short term memory, forgetting words

Apr 30, 2011 (Started Nov 04, 2007)

  • Effectiveness
    Major (for stiffness/spasticity)
  • Side effects
    Moderate (forgetting words, loss of short term memory, memory problems)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I HAVE FOUND NO PROBLEMS MANAGING IT. HOWEVER A SIDE EFFECT OF WHICH I WAS UNAWARE HAS BEEN INCREASING MEMORY PROBLEMS & SOME CONFUSION. I AM CURRENTLY PHASING OUT THE DRUG & AS I'M STILL ON AGONISTS (REQUIP) I'M CONCERNED THAT I WILL START DOPAMINS
Cost: < $25 monthly
Side effects: memory problems, loss of short term memory, forgetting words

May 25, 2010 (Started Nov 04, 2007)

  • Effectiveness
    Major (for stiffness/spasticity)
  • Side effects
    Moderate (forgetting words, loss of short term memory, memory problems)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 300 mg Daily
Advice & Tips: WITH MY CONSULTANT & PD NURSE I AM REDUCING THE DOSE OVER TIME AS THE SIDE-EFFECTS HAVE BECOME DISTRESSING - MAINLY CONFUSION & LOSS OF SHORT-TERM MEMORY
Cost: < $25 monthly
Side effects: memory problems, loss of short term memory, forgetting words

Jun 9, 2009 (Started Nov 04, 2007)

  • Effectiveness
    Major (for stiffness/spasticity)
  • Side effects
    Moderate (forgetting words, loss of short term memory, memory problems)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 300 mg Daily
Cost: < $25 monthly
Side effects: memory problems, loss of short term memory, forgetting words

  • 0 helpful marks

Feb 8, 2011 (Started Dec 31, 2010)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    Mild
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: As needed
Cost: < $25 monthly

  • 0 helpful marks

Nov 24, 2009 (Started Mar 21, 2009)

  • Effectiveness
    Slight (for Other)
  • Side effects
    Moderate (chronic constipation, bowel incontinence)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Need different muscle relaxer
Side effects: chronic constipation, bowel incontinence

  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Orphenadrine