What is Valproate Sodium?

Category: Prescription Drugs

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Sodium valproate or valproate sodium is the sodium salt of valproic acid and is an anticonvulsant used in the treatment of epilepsy and bipolar disorder, as well as other psychiatric conditions requiring the administration of a mood stabilizer.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 96 53
Bipolar disorder 61 68
Bipolar manic episodes 23 26
Bipolar II disorder 9 4
Fibromyalgia 5 2
Anxious mood 4 1

Show all 54 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
27
Moderate
49
Mild
33
None
55

Commonly reported side effects and conditions associated with Valproate Sodium

Side effect Patients
Weight gain 28
Drowsiness 9
Hair loss 8
Fatigue 7
Nausea 6
Tiredness 6

Show all 91 reported side effects

Dosages

Based on patients currently taking Valproate Sodium

Dosage Patients
500 mg daily 3
600 mg daily 2
500 mg twice daily 2
600 mg twice daily 2
1 tablet(s) daily 1
2 tablet(s) daily 1
2 capsule(s) twice daily 1
15 mg daily 1
150 mg daily 1
400 mg daily 1

See all 19 dosages

Why patients stopped taking Valproate Sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 28
Doctor's advice 21
Did not seem to work 20
Other 12
Course of treatment ended 5
Personal research 3
Expense 2
Change in health plan coverage 1
See all 63 patients who've stopped taking Valproate Sodium

Duration

Currently taking Valproate Sodium

Duration Patients
1 - 6 months 1
1 - 2 years 1
2 - 5 years 8
5 - 10 years 9
10 years or more 5

Stopped taking Valproate Sodium

Duration Patients
Less than 1 month 11
1 - 6 months 16
6 months - 1 year 7
1 - 2 years 8
2 - 5 years 12
5 - 10 years 7
10 years or more 3
Adherence
Adherence Evaluations
Always 124
Usually 30
Sometimes 6
Never taken as prescribed 4
Burden
Burden Evaluations
Very hard to take 12
Somewhat hard to take 20
A little hard to take 39
Not at all hard to take 93
Cost per month
Cost per month Evaluations
$200+ 0
$100-199 3
$50-99 3
$25-49 5
< $25 50
Not specified 103

What people switch to and from

Patients started taking Valproate Sodium after stopping:

Treatment Patients
Lamotrigine (Lamictal) 4
Lithium Carbonate (Lithium Carbonate ER) 4
Carbamazepine (Tegretol) 2
Quetiapine (Seroquel) 2
Alprazolam (Xanax) 1

Show all 14 treatments patients report switching from

Patients stopped taking Valproate Sodium and switched to:

Treatment Patients
Carbamazepine (Tegretol) 3
Lamotrigine (Lamictal) 2
Levetiracetam (Keppra) 1
Lithium Carbonate (Lithium Carbonate ER) 1
Paroxetine (Paxil) 1

Show all 9 treatments patients report switching to

Last updated:

7 patient evaluations for Valproate Sodium

Jun 28, 2012 (Started Apr 12, 1968)

  • Effectiveness
    Moderate (for epilepsy)
  • Side effects
    Moderate (nausea)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 1600 mg Daily
Advice & Tips: Lot of tablets (8 per day)
Cost: < $25 monthly

  • 0 helpful marks

Jul 21, 2011 (Started Jan 06, 2008)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 500 mg Daily
Advice & Tips: It is a remedy, which stabilizes a chemical condition and prevents from too sudden mood swings, so that having some experience you can notice and evaluate moods and - especially - overexcited and hyperactive emotional boosts. The remedy is effective in preventing manic conditions, though there is quite a lot of way to go in psychotherapy, healthy lifestyle, sports, positive attitudes, meditation or other methods in case of depression. But, again, the remedy helps to keep balance when some euphoria arises with the improvement of condition - and this is quite natural, as these are very positive emotions, when your hopes to get out of depressive states start to fulfill. So when taken regularly (obviously, in case of depression, mania or normal states), it is a lot of help in stability, which a lot of people who fought bipolar disorder more or less successfully in the past just didn't have.
Cost: < $25 monthly

Jan 2, 2009 (Started Jan 06, 2008)

  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 500 mg Daily
Advice & Tips: "Depakine" was effective when I had mania period. Yet constant use of it is more of a prevention against mania or other mood swings. It hadn't had any effect for depression and anxiety for me.
Cost: < $25 monthly

  • 0 helpful marks

Jul 21, 2011 (Started Mar 17, 2011)

  • Effectiveness
    Moderate (for bipolar II disorder)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 750 mg Daily
Advice & Tips: I have found that since taking this treatment i have been able on good days sleep better and i have found that my thoughts are more stable and less busy and all over the place.. I have found that i feel more on a general mood level rather than just being right up or right down so with this i find that if im having a low day that i can cope with it better.

  • 0 helpful marks
Last updated:
Showing 3 of 7 patient evaluations for Valproate Sodium