What is Riluzole?

Category: Prescription Drugs

Most popular types: Rilutek

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Riluzole is a drug used to treat amyotrophic lateral sclerosis (ALS). Riluzole does not cure ALS or improve symptoms, but may extend survival or the time to tracheostomy.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Amyotrophic lateral sclerosis 2,160 1,077
Primary lateral sclerosis 53 35
Progressive muscular atrophy 41 33
General health 14 9
Stiffness/spasticity 8 3
Muscle twitching (fasciculations) 7 4

Show all 21 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
85
Moderate
101
Mild
159
None
789

Commonly reported side effects and conditions associated with Riluzole

Side effect Patients
Fatigue 51
Nausea 38
Elevated liver enzymes 21
Tiredness 18
Stomach pain 13
Abdominal pain 9

Show all 140 reported side effects

Dosages

Based on patients currently taking Riluzole

Dosage Patients
50 mg twice daily 208
100 mg daily 65
50 mg daily 21
100 mg twice daily 15
daily 3
50 mg three times daily 2
10 mg daily 1
30 g twice daily 1
150 mg daily 1
50 mg four times daily 1

See all 12 dosages

Why patients stopped taking Riluzole

Multiple reasons could be selected

Reason Patients
Side effects too severe 238
Did not seem to work 202
Expense 89
Doctor's advice 78
Other 66
Personal research 57
Change in health plan coverage 16
Course of treatment ended 14
See all 547 patients who've stopped taking Riluzole

Duration

Currently taking Riluzole

Duration Patients
1 - 6 months 10
6 months - 1 year 33
1 - 2 years 96
2 - 5 years 102
5 - 10 years 55
10 years or more 29

Stopped taking Riluzole

Duration Patients
Less than 1 month 87
1 - 6 months 169
6 months - 1 year 75
1 - 2 years 99
2 - 5 years 98
5 - 10 years 21
10 years or more 3
Adherence
Adherence Evaluations
Always 943
Usually 92
Sometimes 26
Never taken as prescribed 73
Burden
Burden Evaluations
Very hard to take 33
Somewhat hard to take 99
A little hard to take 181
Not at all hard to take 821
Cost per month
Cost per month Evaluations
$200+ 115
$100-199 46
$50-99 80
$25-49 125
< $25 415
Not specified 353

What people switch to and from

Patients started taking Riluzole after stopping:

Treatment Patients
Intravenous Immunoglobulin (IVIG) (Gammaglobulin (IVIg)) 1
Lunasin (Lunasin Duke Virtual Trial) 1
Prednisone (Deltasone) 1

Patients stopped taking Riluzole and switched to:

Treatment Patients
Baclofen (Mylan-Baclofen) 2
Edaravone (Radicava) 1
Last updated:

110 patient evaluations for Riluzole

Feb 15, 2018 (Started Dec 15, 2017)

  • Effectiveness
    Moderate (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily

  • 0 helpful marks

Jan 15, 2018 (Started Jan 01, 2002)

  • Effectiveness
    Slight (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: It is impossible to evaluate the effectiveness for oneself. However, statistical studies do show it extends life expectancy. I would start ASAP after diagnosis.
Cost: < $25 monthly

  • 0 helpful marks

May 31, 2017 (Started Sep 08, 2015)

  • Effectiveness
    Can't tell (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Twice daily
Cost: < $25 monthly

Aug 14, 2016 (Started Sep 08, 2015)

  • Effectiveness
    Can't tell (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Twice daily
Advice & Tips: How could you even begin to evaluate such a subjective drug.
Cost: < $25 monthly

Apr 27, 2016 (Started Sep 08, 2015)

  • Effectiveness
    Can't tell (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Twice daily
Cost: < $25 monthly

Nov 26, 2015 (Started Sep 08, 2015)

  • Effectiveness
    Can't tell (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Twice daily
Cost: < $25 monthly

Nov 6, 2015 (Started Sep 08, 2015)

  • Effectiveness
    Can't tell (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Twice daily
Advice & Tips: I am not sure of what effects I am looking for but I feel no different than when I was not taking the drug. The only thing that does come to mind is that maybe don't cramp up as much.

  • 0 helpful marks
Last updated:
Showing 3 of 110 patient evaluations for Riluzole