What is Promethazine?

Category: Prescription Drugs

Most popular types: Phenergan Promethegan Phenadoz Show all

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See also: Promethazine DM

Promethazine is an antiemetic and antihistamine. It is used to relieve the symptoms of allergic reactions, nausea, motion sickness. It is also use as a sedative, as adjunctive therapy for postoperative pain, anesthetic and anaphylactic reactions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Nausea 255 70
Nausea and vomiting 160 56
Gastroparesis 50 14
Migraine headaches 38 16
Insomnia 19 5
Migraine 10 8

Show all 89 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 11
Moderate 29
Mild 54
None 74

Commonly reported side effects and conditions associated with Promethazine

Side effect Patients
Drowsiness 30
Sleepiness 10
Excessive daytime sleepiness (somnolence) 6
Fatigue 6
Tiredness 5
Dry mouth 3

Show all 40 reported side effects

Dosages

Based on patients currently taking Promethazine

Dosage Patients
25mg as needed 27
25 mg daily 7
25mg/mL as needed 7
12.5mg as needed 5
25 mg four times daily 4
12.5 mg daily 3
50 mg daily 2
100 mg daily 2
10mg as needed 2
50mg as needed 2

See all 24 dosages

Why patients stopped taking Promethazine

Multiple reasons could be selected

Reason Patients
Course of treatment ended 34
Doctor's advice 32
Other 24
Side effects too severe 23
Did not seem to work 22
Change in health plan coverage 3
Expense 1
See all 116 patients who’ve stopped taking Promethazine

Duration

Currently taking Promethazine

Duration Patients
1 - 6 months 2
6 months - 1 year 6
1 - 2 years 6
2 - 5 years 25
5 - 10 years 25
10 years or more 9

Stopped taking Promethazine

Duration Patients
Less than 1 month 33
1 - 6 months 22
6 months - 1 year 16
1 - 2 years 15
2 - 5 years 16
5 - 10 years 9
10 years or more 7
Adherence
Adherence Evaluations
Always 110
Usually 28
Sometimes 25
Never taken as prescribed 5
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 9
A little hard to take 19
Not at all hard to take 137
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 0
$50-99 0
$25-49 5
< $25 87
Not specified 73

What people switch to and from

Patients started taking Promethazine after stopping:

Treatment Patients
Ondansetron (Zofran) 12
Meclizine (Antivert) 2
Prochlorperazine (Compazine) 2
Carbamazepine (Tegretol) 1
Gabapentin (Neurontin) 1

Show all 8 treatments patients report switching from

Patients stopped taking Promethazine and switched to:

Treatment Patients
Ondansetron (Zofran) 18
Prochlorperazine (Compazine) 2
Cetirizine-pseudoephedrine (Zyrtec-D) 1
Medical marijuana (Cannabidiol/Tetrahydrocannabinol Balanced Mixture) 1
Zopiclone (Imovane) 1
Last updated:

20 patient evaluations for Promethazine

137 members have decided to share their profiles only with other members of PatientsLikeMe.

NanaBurr
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NanaBurr
Data Quality: 2 stars
  • Gender: F
  • Age: 46
Condition: Systemic Lupus Erythematosus 12 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Moderate
I am: g
I have:
Systemic Lupus Erythematosus

See NanaBurr's full Promethazine history

Feb 15, 2016 (Started Sep 26, 2015)

  • Effectiveness
    Major (for Nausea and vomiting)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks
tigger13039
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tigger13039
Sex: M
Data Quality: 2 stars
Sensation: Moderate
Overall: Mild
Cognition: moderate
Vision: mild
Speech: moderate
Swallowing: mild
Upper limb: mild
Walking: moderate
I am: g
I have:
MS

See tigger13039's full Promethazine history

Dec 1, 2015 (Started Feb 24, 2011)

  • Effectiveness
    Moderate (for Nausea and vomiting)
  • Effectiveness
    Moderate (for Nausea)
  • Effectiveness
    None (for Multiple Sclerosis)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Fluff4brains
66962 thumb
Fluff4brains
Data Quality: 1 star
  • Gender: M
  • Age: 50
Condition: Glioblastoma 6 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Moderate
I am: b
I have:
Glioblastoma

See Fluff4brains's full Promethazine history

Feb 15, 2015 (Started Feb 15, 2015)

  • Effectiveness
    Slight (for Insomnia)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 12.5 mg Daily
Advice & Tips: As an OTC drug did ty doubling tho dose makes earle morning grogyy an unrefreshed, aLso still wokken for nighttime loo trips though my father claims the opposite for him basically(he finds it tends to dry up nocturnal pee break not quitd) Overall strong not really enough for me to get over the dexamethasone 4mg evening buzz.

  • 0 helpful marks
Last updated:
Showing 3 of 20 patient evaluations for Promethazine