What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,339 1,327
Depressed mood 1,631 812
Persistent depressive disorder (dysthymia) 409 337
Mild depression 155 69
Anxious mood 121 64

Show all 185 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 281
Moderate 388
Mild 631
None 1,156

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 110
Anxious mood 72
Weight gain 59
Insomnia 54
Headaches 48
Constipation 43

Show all 364 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 167
150 mg daily 119
100 mg daily 65
300 mg/24 hours daily 54
450 mg daily 49
75 mg daily 42
150 mg twice daily 35
100 mg twice daily 24
150 mg/24 hours daily 21
200 mg twice daily 17

See all 58 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 670
Side effects too severe 565
Doctor's advice 441
Other 282
Course of treatment ended 96
Expense 84
Personal research 73
Change in health plan coverage 45
See all 1642 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
1 - 6 months 33
6 months - 1 year 40
1 - 2 years 101
2 - 5 years 190
5 - 10 years 184
10 years or more 161

Stopped taking Bupropion

Duration Patients
Less than 1 month 362
1 - 6 months 365
6 months - 1 year 238
1 - 2 years 234
2 - 5 years 289
5 - 10 years 127
10 years or more 65
Adherence
Adherence Evaluations
Always 1927
Usually 362
Sometimes 51
Never taken as prescribed 116
Burden
Burden Evaluations
Very hard to take 84
Somewhat hard to take 149
A little hard to take 346
Not at all hard to take 1877
Cost per month
Cost per month Evaluations
$200+ 16
$100-199 27
$50-99 86
$25-49 178
< $25 1169
Not specified 980

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 95
Fluoxetine (Prozac) 93
Venlafaxine (Effexor XR) 75
Citalopram (Celexa) 55
Duloxetine (Cymbalta) 49

Show all 55 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 52
Sertraline (Zoloft) 49
Venlafaxine (Effexor XR) 36
Citalopram (Celexa) 33
Escitalopram (Lexapro) 32

Show all 48 treatments patients report switching to

Last updated:

188 patient evaluations for Bupropion

Jul 8, 2018 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 175 mg Daily
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Dec 18, 2013 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (ringing in ears (tinnitus))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Oct 20, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Aug 30, 2010 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

Jul 16, 2009 (Started Jul 03, 2018)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly
Side effects: ringing in ears (tinnitus)

  • 0 helpful marks

Apr 11, 2018 (Started May 15, 2017)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Cost: $200+ monthly

  • 0 helpful marks

Jan 12, 2018 (Started Jun 30, 2017)

  • Effectiveness
    Moderate (for chronic fatigue)
  • Side effects
    Severe (vomiting, nausea)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 188 patient evaluations for Bupropion