What is Divalproex sodium?

Category: Prescription Drugs

Most popular types: Depakote Depakote ER Divalproex ER Show all

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Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Epilepsy 557 266
Bipolar Disorder 328 195
Migraine headaches 108 59
Bipolar manic episodes 45 34
Bipolar I Disorder 44 31
Bipolar II Disorder 41 33

Show all 128 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 164
Moderate 192
Mild 178
None 159

Commonly reported side effects and conditions associated with Divalproex sodium

Side effect Patients
Weight gain 132
Hair loss 42
Fatigue 37
Drowsiness 25
Tremor in hands 20
Nausea 19

Show all 264 reported side effects

Dosages

Based on patients currently taking Divalproex sodium

Dosage Patients
500 mg twice daily 24
1,000 mg daily 23
500 mg daily 20
1,500 mg daily 19
250 mg daily 15
250 mg twice daily 15
500 mg three times daily 9
750 mg daily 8
2,000 mg daily 7
1,000 mg twice daily 6

See all 28 dosages

Why patients stopped taking Divalproex sodium

Multiple reasons could be selected

Reason Patients
Side effects too severe 307
Did not seem to work 222
Doctor's advice 152
Other 101
Personal research 33
Expense 27
Course of treatment ended 21
Change in health plan coverage 8
See all 569 patients who’ve stopped taking Divalproex sodium

Duration

Currently taking Divalproex sodium

Duration Patients
Less than 1 month 2
1 - 6 months 13
6 months - 1 year 17
1 - 2 years 26
2 - 5 years 37
5 - 10 years 42
10 years or more 41

Stopped taking Divalproex sodium

Duration Patients
Less than 1 month 99
1 - 6 months 132
6 months - 1 year 69
1 - 2 years 77
2 - 5 years 114
5 - 10 years 39
10 years or more 47
Adherence
Adherence Evaluations
Always 548
Usually 109
Sometimes 21
Never taken as prescribed 15
Burden
Burden Evaluations
Very hard to take 52
Somewhat hard to take 110
A little hard to take 111
Not at all hard to take 420
Cost per month
Cost per month Evaluations
$200+ 19
$100-199 18
$50-99 31
$25-49 57
< $25 270
Not specified 298

What people switch to and from

Patients started taking Divalproex sodium after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 30
Lamotrigine (Lamictal) 13
Topiramate (Topamax) 10
Aripiprazole (Abilify) 8
Sertraline (Zoloft) 6

Show all 40 treatments patients report switching from

Patients stopped taking Divalproex sodium and switched to:

Treatment Patients
Lamotrigine (Lamictal) 24
Carbamazepine (Tegretol) 10
Lithium Carbonate (Lithium Carbonate ER) 9
Oxcarbazepine (Trileptal) 8
Levetiracetam (Keppra) 7

Show all 29 treatments patients report switching to

Last updated:

67 patient evaluations for Divalproex sodium

537 members have decided to share their profiles only with other members of PatientsLikeMe.

LadySirona
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LadySirona
Gender: F
Data Quality: 3 stars
Depression: 3
Mania: 2
Emotional: 2
Anxiety: 3
Compulsion: 3
External Stress: Overwhelming
58 F
Function: Low
Distress: High
I am: n
I have:
Bipolar Disorder

See LadySirona's full Divalproex sodium history

May 10, 2017 (Started Mar 09, 2017)

  • Effectiveness
    Moderate (for Bipolar Disorder)
  • Side effects
    Severe (Very low white blood cell count)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 500 mg Daily
Advice & Tips: had to sto[ WBC dropped to 3
Cost: < $25 monthly

  • 0 helpful marks
COOPERATI
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COOPERATI
Gender: M
Data Quality: 2 stars
Depression: 3
Mania: 2
Emotional: 4
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
43 M
Function: Low
Distress: High
I am: vb
I have:
Schizophrenia

See COOPERATI's full Divalproex sodium history

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 250 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Side effects
    Severe
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 250 mg All the time (24/7)

  • 0 helpful marks
Just 4 You
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Just 4 You
Data Quality: 2 stars
  • Gender: M
  • Age: 54y
  • Duration: 52 yrs
PRO survey: PRO 3
Quality of life:
  • Mental: None
  • Physical: Mild
0 seizures
12 weeks ago
I am: vg
I have:
Epilepsy

See Just 4 You's full Divalproex sodium history

Sep 23, 2016 (Started Feb 28, 2015)

  • Effectiveness
    Major (for Epilepsy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 67 patient evaluations for Divalproex sodium