- Can't tell
You should not use silodosin if you have:
- severe kidney disease;
- severe liver disease; or
- if you are also using ketoconazole (Nizoral), itraconazole (Sporanox), or ritonavir (Norvir).
If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking silodosin, tell your doctor if you are allergic to any drugs, or if you have:
- kidney disease;
- liver disease;
- prostate cancer; or
- if you are taking another alpha-blocker such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax), or terazosin (Hytrin) for high blood pressure or prostate problems.
FDA pregnancy category B. Although silodosin is not for use in women, this medication is not expected to be harmful to an unborn baby. If you are a woman using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether silodosin passes into breast milk, or if it could harm a nursing baby. If you are a woman using this medication, do not take silodosin without telling your doctor if you are breast-feeding a baby.
Silodosin can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose can cause severe dizziness, or fainting.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using silodosin and call your doctor at once if you have a serious side effect such as:
- severe dizziness;
- feeling like you might pass out;
- jaundice (yellowing of the skin or eyes); or
- penis erection that is painful or lasts 4 hours or longer.
Less serious side effects may include:
- mild dizziness, weakness;
- sleep problems (insomnia);
- diarrhea, stomach pain;
- decreased amount of semen released during sex; or
- runny or stuffy nose, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medications you use, especially:
- conivaptan (Vaprisol);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- imatinib (Gleevec);
- isoniazid (for treating tuberculosis);
- an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);
- an antifungal medication such as clotrimazole (Mycelex Troche) or voriconazole (Vfend);
- heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), nicardipine (Cardene), quinidine (Quinaglute, Quinidex, Quin-Release), or verapamil (Calan, Covera, Isoptin, Verelan);
- HIV/AIDS medicine such as amprenavir (Agenerase), atazanavir (Reyataz), delavirdine (Rescriptor), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase, Fortovase), or ritonavir (Norvir);
- an antidepressant such as nefazodone;
- any other medicine to treat high blood pressure or prostate problems.
This list is not complete and there may be other drugs that can interact with silodosin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Rapaflo and silodosin
Available Strengths & Dosages
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Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04