What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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See also: Lidocaine-prilocaine-meloxicam-lamotrigine cream

Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
bipolar disorder 1,392 810
epilepsy 1,075 508
bipolar II disorder 701 433
bipolar I disorder 419 263
Depressed mood 153 100
borderline personality disorder 145 92

Show all 217 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 247
Moderate 393
Mild 559
None 892

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 67
Headaches 67
Weight gain 67
Nausea 49
Insomnia 46
Problems concentrating 45

Show all 514 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 158
100 mg daily 93
25 mg daily 69
150 mg daily 63
50 mg daily 48
200 mg twice daily 46
300 mg daily 44
100 mg twice daily 43
400 mg daily 41
150 mg twice daily 27

See all 71 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 416
Did not seem to work 383
Doctor's advice 251
Other 186
Expense 64
Personal research 53
Course of treatment ended 39
Change in health plan coverage 31
See all 957 patients who've stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 2
1 - 6 months 60
6 months - 1 year 87
1 - 2 years 143
2 - 5 years 192
5 - 10 years 187
10 years or more 113

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 202
1 - 6 months 227
6 months - 1 year 155
1 - 2 years 130
2 - 5 years 158
5 - 10 years 86
10 years or more 15
Adherence
Adherence Evaluations
Always 1703
Usually 270
Sometimes 46
Never taken as prescribed 72
Burden
Burden Evaluations
Very hard to take 92
Somewhat hard to take 189
A little hard to take 350
Not at all hard to take 1460
Cost per month
Cost per month Evaluations
$200+ 42
$100-199 48
$50-99 64
$25-49 115
< $25 969
Not specified 853

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 79
Quetiapine (Seroquel) 44
Divalproex sodium (Depakote) 42
Aripiprazole (Abilify) 38
Bupropion (Wellbutrin XL) 18

Show all 53 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 36
Quetiapine (Seroquel) 20
Aripiprazole (Abilify) 19
Divalproex sodium (Depakote) 11
Lurasidone (Latuda) 9

Show all 51 treatments patients report switching to

Last updated:

138 patient evaluations for Lamotrigine

Christina22222
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Christina22222
Data Quality: 3 stars
  • Gender: F
  • Age: 45
Condition: TBI 3 additional condition(s)
Quality of life:
  • Mental: None
  • Physical: None
I am: vg
I have:
TBI

See Christina22222's full Lamotrigine history

May 20, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Can’t tell (for epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Twice daily
Advice & Tips: I could barely walk when my dose got up to 2 tablets twice a day.
Cost: $25-49 monthly

Feb 5, 2017 (Started Dec 23, 2016)

  • Effectiveness
    Slight (for Seizures)
  • Effectiveness
    Slight (for epilepsy)
  • Side effects
    Severe (Loss of balance)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Twice daily
Cost: $25-49 monthly

  • 0 helpful marks
COOPERATI
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COOPERATI
Gender: M
Data Quality: 2 stars
Depression: 3
Mania: 2
Emotional: 4
Anxiety: 2
Compulsion: 2
External Stress: Overwhelming
43 M
Function: Low
Distress: High
I am: vb
I have:
Schizophrenia

See COOPERATI's full Lamotrigine history

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Effectiveness
    Major (for Bipolar rapid cycling)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg All the time (24/7)

  • 0 helpful marks
zoomer
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zoomer
Gender: F
Data Quality: 3 stars
Depression: 0
Mania: 0
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Moderate
61 F
Function: High
Distress: Low
I am: g
I have:
bipolar I disorder

See zoomer's full Lamotrigine history

Feb 6, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it. I have been taking 400mg since 2006.Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIG time. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Nov 29, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar I disorder)
  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: I am on a high dose. (400mg a day) I think that is notable since some evaluations of this medication are negative but that seems to be people taking very small doses. Not even therapeutic level ?
Cost: < $25 monthly

Apr 6, 2011 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has helped to stabilize my moods to an even greater extent than originally given credit for. I had a short time on half dose and the increase in mood swings and loss of emotional control returned BIGtime. I have experienced none of the reported side effects .. This medication gives me a sense of balance and curbs the extreme shifts, as in rapid cycling.
Cost: < $25 monthly

Oct 25, 2010 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal has been like a miracle in stabilizing my moods. my moods have more level consistently since starting Lamictal. I love it.
Cost: < $25 monthly

Oct 24, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Lamictal continues to work as an effective mood stabilizer, my last depressive episode due to med changes was not severe as episodes before Lamictal. No side effects at this high dose either.
Cost: < $25 monthly

Aug 13, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Given time all negative side effects I may have experienced have disappeared. This medication is an effective mood stabilizer in my regime of meds.

Jul 26, 2009 (Started Jan 01, 2006)

  • Effectiveness
    Major (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Cost: < $25 monthly

  • 2 helpful marks
Last updated:
Showing 3 of 138 patient evaluations for Lamotrigine