What is Lamotrigine?

Category: Prescription Drugs

Most popular types: Lamictal Lamictal XR Lamictal Blue Show all

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Lamotrigine is an anticonvulsant that is used alone or in combination with other medications to treat seizures in adults and children who are at least 2 years old. Lamotrigine is also used as maintenance treatment for bipolar I disorder.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Bipolar Disorder 1,109 591
Epilepsy 1,060 483
Bipolar II Disorder 576 332
Bipolar I Disorder 357 211
Depressed mood 140 91
Borderline Personality Disorder 126 71

Show all 207 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 201
Moderate 345
Mild 474
None 709

Commonly reported side effects and conditions associated with Lamotrigine

Side effect Patients
Dizziness 65
Headaches 59
Weight gain 52
Insomnia 44
Nausea 43
Problems concentrating 41

Show all 471 reported side effects

Dosages

Based on patients currently taking Lamotrigine

Dosage Patients
200 mg daily 91
100 mg daily 55
25 mg daily 37
150 mg daily 33
300 mg daily 32
100 mg twice daily 26
200 mg twice daily 26
400 mg daily 24
50 mg daily 22
150 mg twice daily 19

See all 50 dosages

Why patients stopped taking Lamotrigine

Multiple reasons could be selected

Reason Patients
Side effects too severe 364
Did not seem to work 350
Doctor's advice 232
Other 165
Expense 58
Personal research 48
Course of treatment ended 34
Change in health plan coverage 30
See all 854 patients who’ve stopped taking Lamotrigine

Duration

Currently taking Lamotrigine

Duration Patients
Less than 1 month 8
1 - 6 months 21
6 months - 1 year 54
1 - 2 years 75
2 - 5 years 129
5 - 10 years 118
10 years or more 62

Stopped taking Lamotrigine

Duration Patients
Less than 1 month 173
1 - 6 months 218
6 months - 1 year 138
1 - 2 years 119
2 - 5 years 136
5 - 10 years 73
10 years or more 13
Adherence
Adherence Evaluations
Always 1410
Usually 231
Sometimes 37
Never taken as prescribed 51
Burden
Burden Evaluations
Very hard to take 75
Somewhat hard to take 165
A little hard to take 297
Not at all hard to take 1192
Cost per month
Cost per month Evaluations
$200+ 39
$100-199 45
$50-99 59
$25-49 105
< $25 806
Not specified 675

What people switch to and from

Patients started taking Lamotrigine after stopping:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 47
Divalproex sodium (Depakote) 25
Quetiapine (Seroquel) 25
Aripiprazole (Abilify) 24
Carbamazepine (Tegretol) 14

Show all 48 treatments patients report switching from

Patients stopped taking Lamotrigine and switched to:

Treatment Patients
Lithium Carbonate (Lithium Carbonate ER) 17
Quetiapine (Seroquel) 13
Aripiprazole (Abilify) 10
Oxcarbazepine (Trileptal) 9
Divalproex sodium (Depakote) 8

Show all 44 treatments patients report switching to

Last updated:

136 patient evaluations for Lamotrigine

1,305 members have decided to share their profiles only with other members of PatientsLikeMe.

charkimber
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charkimber
Gender: F
Data Quality: 3 stars
Depression: 1
Mania: 1
Emotional: 1
Anxiety: 1
Compulsion: 1
External Stress: Moderate
56 F
Function: High
Distress: Low
I am: g
I have:
Bipolar II

See charkimber's full Lamotrigine history

Jan 18, 2017 (Started Jul 01, 2009)

  • Effectiveness
    Major (for Bipolar II Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Don't go off without talking to doctor. I came out of the fog after starting this medication.

  • 0 helpful marks
one_step_closer
3397 thumb
one_step_closer
Gender: F
Data Quality: 3 stars
Depression: 2
Mania: 0
Emotional: 2
Anxiety: 4
Compulsion: 2
External Stress: Low
30 F
Function: Moderate
Distress: Moderate
I am: b
I have:
Borderline Personality

See one_step_closer's full Lamotrigine history

Aug 10, 2016 (Started Oct 25, 2012)

  • Effectiveness
    Can’t tell (for Major Depressive Disorder)
  • Effectiveness
    Can’t tell (for Borderline Personality Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Srs2388
85822 thumb
Srs2388
Data Quality: 1 star
  • Gender: M
  • Age: 28y
  • Duration: ? yrs
Quality of life:
  • Mental: Severe
  • Physical: Severe
2 seizures
1 week ago
I am: vb
I have:
Epilepsy

See Srs2388's full Lamotrigine history

Jun 30, 2016 (Started Jul 01, 2014)

  • Effectiveness
    None (for Treat side effects of another treatment)
  • Effectiveness
    Can’t tell (for Epilepsy)
  • Side effects
    Severe (Suicide attempt, Rashes (redness, swelling), Lethargy, Memory and cognition problems)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Advice & Tips: Make depression worse, and a rash.

Jan 3, 2016 (Started Jul 01, 2014)

  • Effectiveness
    None (for Treat side effects of another treatment)
  • Effectiveness
    Can’t tell (for Epilepsy)
  • Side effects
    Moderate (Suicide attempt, Rashes (redness, swelling), Lethargy, Memory and cognition problems)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily
Advice & Tips: This will destroy your memory and leave you feeling tired all the time. 

Apr 13, 2015 (Started Jul 01, 2014)

  • Effectiveness
    Can’t tell (for Treat side effects of another treatment)
  • Effectiveness
    Can’t tell (for Epilepsy)
  • Side effects
    Moderate (Suicide attempt, Rashes (redness, swelling), Lethargy, Memory and cognition problems)
  • Adherence
    Sometimes
  • Burden
    Very hard to take
Dosage: 100 mg Twice daily

  • 0 helpful marks
Last updated:
Showing 3 of 136 patient evaluations for Lamotrigine