What is Promethazine?

Category: Prescription Drugs

Most popular types: Phenergan Promethegan Phenadoz Show all

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See also: Promethazine DM

Promethazine is an antiemetic and antihistamine. It is used to relieve the symptoms of allergic reactions, nausea, motion sickness. It is also use as a sedative, as adjunctive therapy for postoperative pain, anesthetic and anaphylactic reactions.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Nausea 258 77
Gastroparesis 52 14
Migraine headaches 39 16
Insomnia 17 5
Anxious mood 9 5

Show all 68 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
11
Moderate
30
Mild
58
None
75

Commonly reported side effects and conditions associated with Promethazine

Side effect Patients
Drowsiness 34
Sleepiness 10
Excessive daytime sleepiness (somnolence) 6
Fatigue 6
Tiredness 5
Blurry vision 2

Show all 41 reported side effects

Dosages

Based on patients currently taking Promethazine

Dosage Patients
25mg as needed 32
25 mg daily 7
12.5mg as needed 4
25mg/mL as needed 4
50 mg daily 3
100 mg daily 3
50mg as needed 3
25 mg twice daily 2
25 mg four times daily 2
1mg as needed 2

See all 26 dosages

Why patients stopped taking Promethazine

Multiple reasons could be selected

Reason Patients
Course of treatment ended 36
Doctor's advice 32
Other 27
Did not seem to work 24
Side effects too severe 24
Change in health plan coverage 3
Expense 1
See all 120 patients who've stopped taking Promethazine

Duration

Currently taking Promethazine

Duration Patients
1 - 6 months 2
6 months - 1 year 6
1 - 2 years 7
2 - 5 years 27
5 - 10 years 22
10 years or more 14

Stopped taking Promethazine

Duration Patients
Less than 1 month 34
1 - 6 months 23
6 months - 1 year 16
1 - 2 years 16
2 - 5 years 16
5 - 10 years 9
10 years or more 8
Adherence
Adherence Evaluations
Always 113
Usually 29
Sometimes 26
Never taken as prescribed 6
Burden
Burden Evaluations
Very hard to take 3
Somewhat hard to take 9
A little hard to take 19
Not at all hard to take 143
Cost per month
Cost per month Evaluations
$200+ 3
$100-199 0
$50-99 0
$25-49 5
< $25 86
Not specified 80

What people switch to and from

Patients started taking Promethazine after stopping:

Treatment Patients
Ondansetron (Zofran) 14
Meclizine (Antivert) 2
Prochlorperazine (Compazine) 2
Carbamazepine (Tegretol) 1
Gabapentin (Neurontin) 1

Show all 8 treatments patients report switching from

Patients stopped taking Promethazine and switched to:

Treatment Patients
Ondansetron (Zofran) 20
Prochlorperazine (Compazine) 2
Cetirizine-pseudoephedrine (Zyrtec-D) 1
Medical marijuana (Cannabidiol/Tetrahydrocannabinol Balanced Mixture) 1
Rizatriptan (Maxalt) 1

Show all 6 treatments patients report switching to

Last updated:

18 patient evaluations for Promethazine

Feb 15, 2016 (Started Sep 26, 2015)

  • Effectiveness
    Major (for nausea and vomiting)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed

  • 0 helpful marks

Dec 1, 2015 (Started Feb 24, 2011)

  • Effectiveness
    Moderate (for nausea and vomiting)
  • Effectiveness
    Moderate (for nausea)
  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 50 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Feb 15, 2015 (Started Feb 15, 2015)

  • Effectiveness
    Slight (for insomnia)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 12.5 mg Daily
Advice & Tips: As an OTC drug did ty doubling tho dose makes earle morning grogyy an unrefreshed, aLso still wokken for nighttime loo trips though my father claims the opposite for him basically(he finds it tends to dry up nocturnal pee break not quitd) Overall strong not really enough for me to get over the dexamethasone 4mg evening buzz.

  • 0 helpful marks
Last updated:
Showing 3 of 18 patient evaluations for Promethazine