What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,939 1,117
Depressed mood 1,530 730
Persistent depressive disorder (dysthymia) 348 287
Mild Depression 140 56
Anxious mood 115 57
Bipolar Disorder 103 86

Show all 209 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 240
Moderate 345
Mild 561
None 987

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 96
Anxious mood 58
Weight gain 51
Insomnia 49
Headaches 47
Constipation 41

Show all 422 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 149
300 mg daily 148
100 mg daily 91
300 mg/24 hours daily 70
75 mg daily 52
450 mg daily 44
100 mg twice daily 43
150 mg twice daily 32
150 mg/24 hours daily 27
200 mg daily 24

See all 81 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 583
Side effects too severe 493
Doctor's advice 381
Other 257
Course of treatment ended 83
Expense 80
Personal research 68
Change in health plan coverage 39
See all 1436 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 75
6 months - 1 year 94
1 - 2 years 141
2 - 5 years 185
5 - 10 years 191
10 years or more 147

Stopped taking Bupropion

Duration Patients
Less than 1 month 289
1 - 6 months 341
6 months - 1 year 228
1 - 2 years 209
2 - 5 years 250
5 - 10 years 109
10 years or more 51
Adherence
Adherence Evaluations
Always 1664
Usually 326
Sometimes 47
Never taken as prescribed 96
Burden
Burden Evaluations
Very hard to take 74
Somewhat hard to take 132
A little hard to take 322
Not at all hard to take 1605
Cost per month
Cost per month Evaluations
$200+ 12
$100-199 25
$50-99 80
$25-49 159
< $25 1041
Not specified 816

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 72
Fluoxetine (Prozac) 61
Venlafaxine (Effexor XR) 58
Duloxetine (Cymbalta) 38
Citalopram (Celexa) 37

Show all 49 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 42
Sertraline (Zoloft) 35
Venlafaxine (Effexor XR) 26
Citalopram (Celexa) 21
Fluoxetine (Prozac) 21

Show all 42 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,637 members have decided to share their profiles only with other members of PatientsLikeMe.

kcj1963
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kcj1963
Sex: M
Data Quality: 2 stars
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: mild
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See kcj1963's full Bupropion history

May 15, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    Mild (Dehydration)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Advice & Tips: not only did this help my attitude, but it increased my libido..:)
Cost: < $25 monthly

Apr 27, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    Mild (Dehydration)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
mountainlion
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mountainlion
Gender: F
Data Quality: 1 star
Depression: 0
Mania: 1
Emotional: 0
Anxiety: 1
Compulsion: 0
External Stress: Moderate
41 F
Function: Moderate
Distress: Low
I am: g
I have:
Bipolar Disorder

See mountainlion's full Bupropion history

Apr 27, 2012 (Started Aug 01, 2006)

  • Effectiveness
    Moderate (for Fatigue)
  • Side effects
    Mild (Weight loss)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks
jiwhite
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jiwhite
Gender: F
Data Quality: 1 star
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Severe
48 F
Function: High
Distress: Low
I am: g
I have:
GAD

See jiwhite's full Bupropion history

Apr 8, 2012 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for Generalized Anxiety Disorder)
  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    Mild (Morning nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I use a pill organizer to keep track of whether or not I have taken my pills for the day and take them at the same time every day. I take pills at night when possible to minimize nausea.
Cost: $100-199 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion