What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

false

Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,594 892
Depressed mood 1,476 693
Persistent depressive disorder (dysthymia) 310 264
Mild Depression 132 51
Anxious mood 113 52
Bipolar Disorder 97 81

Show all 203 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 212
Moderate 296
Mild 491
None 842

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 84
Anxious mood 52
Insomnia 44
Weight gain 40
Constipation 38
Headaches 38

Show all 384 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 86
300 mg daily 74
300 mg/24 hours daily 69
100 mg daily 49
150 mg/24 hours daily 34
450 mg daily 29
75 mg daily 27
100 mg twice daily 26
200 mg daily 21
150 mg twice daily 16

See all 59 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 512
Side effects too severe 440
Doctor's advice 353
Other 241
Expense 76
Course of treatment ended 75
Personal research 62
Change in health plan coverage 34
See all 1294 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 3
1 - 6 months 26
6 months - 1 year 50
1 - 2 years 92
2 - 5 years 140
5 - 10 years 143
10 years or more 86

Stopped taking Bupropion

Duration Patients
Less than 1 month 249
1 - 6 months 315
6 months - 1 year 198
1 - 2 years 191
2 - 5 years 232
5 - 10 years 105
10 years or more 44
Adherence
Adherence Evaluations
Always 1441
Usually 297
Sometimes 41
Never taken as prescribed 62
Burden
Burden Evaluations
Very hard to take 61
Somewhat hard to take 111
A little hard to take 282
Not at all hard to take 1387
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 22
$50-99 73
$25-49 149
< $25 897
Not specified 690

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 50
Fluoxetine (Prozac) 39
Venlafaxine (Effexor XR) 36
Duloxetine (Cymbalta) 30
Citalopram (Celexa) 23

Show all 36 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 30
Sertraline (Zoloft) 23
Venlafaxine (Effexor XR) 17
Citalopram (Celexa) 15
Bupropion (Wellbutrin XL) 13

Show all 34 treatments patients report switching to

Last updated:

183 patient evaluations for Bupropion

1,380 members have decided to share their profiles only with other members of PatientsLikeMe.

jiwhite
Portrait default thumb
jiwhite
Gender: F
Data Quality: 1 star
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Severe
48 F
Function: High
Distress: Low
I am: g
I have:
GAD

See jiwhite's full Bupropion history

Apr 8, 2012 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for Generalized Anxiety Disorder)
  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    Mild (Morning nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I use a pill organizer to keep track of whether or not I have taken my pills for the day and take them at the same time every day. I take pills at night when possible to minimize nausea.
Cost: $100-199 monthly

  • 0 helpful marks
lilybet
4948 thumb
lilybet
Gender: F
Data Quality: 1 star
Depression: 1
Mania: 0
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Overwhelming
57 F
Function: Moderate
Distress: Low
I am: n
I have:
Major Depressive Disorder

See lilybet's full Bupropion history

Feb 23, 2012 (Started Mar 24, 2006)

  • Effectiveness
    Slight (for Reactive Depression)
  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Effectiveness
    Slight (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 400 mg Daily
Advice & Tips: I really can't tell if Wellbutrin is helping me or not. The last several years have been so difficult for me that I'm not sure anything can help except time (and good psychotherapy!)
Cost: < $25 monthly

Sep 15, 2011 (Started Mar 24, 2006)

  • Effectiveness
    None (for Treat my mood condition(s))
  • Effectiveness
    None (for Reactive Depression)
  • Effectiveness
    None (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 400 mg Daily
Advice & Tips: I've been taking Wellbutrin since 2006. Since I've had several severe depression episodes since then, I really don't think it is helping at all.
Cost: < $25 monthly

Sep 9, 2008 (Started Mar 24, 2006)

  • Effectiveness
    Can’t tell (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Well, I'm still depressed somewhat. But the reasons for it are more than biochemical, so I'm taking the med. Who knows what kind of shape I'd be in without it? (previously, bad!)
Cost: < $25 monthly

  • 1 helpful mark
Anna-Magdalena
15739 thumb
new ASD member
Data Quality: 1 star
65 years
Female
g
ATEC
  • Speech: 3
  • Sociability: 14
  • Sensory/Cognitive Awareness: 12
  • Health/Physical Behavior: 8
  • ATEC score: 37
I have:
Autism

See Anna-Magdalena's full Bupropion history

Feb 9, 2012 (Started Mar 29, 2011)

  • Effectiveness
    Can’t tell (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg/24 hours Daily

Sep 6, 2011 (Started Mar 29, 2011)

  • Effectiveness
    Can’t tell (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 150 mg/24 hours Daily

  • 0 helpful marks
Last updated:
Showing 3 of 183 patient evaluations for Bupropion