What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,823 1,049
Depressed mood 1,514 720
Persistent depressive disorder (dysthymia) 339 285
Mild Depression 138 55
Anxious mood 114 55
Bipolar Disorder 101 85

Show all 206 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 232
Moderate 333
Mild 543
None 944

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 93
Anxious mood 55
Weight gain 49
Insomnia 46
Headaches 42
Constipation 41

Show all 412 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 134
300 mg daily 127
100 mg daily 80
300 mg/24 hours daily 70
450 mg daily 47
100 mg twice daily 38
75 mg daily 37
150 mg/24 hours daily 31
200 mg daily 28
150 mg twice daily 26

See all 69 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 562
Side effects too severe 478
Doctor's advice 369
Other 249
Course of treatment ended 81
Expense 78
Personal research 68
Change in health plan coverage 36
See all 1386 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 54
6 months - 1 year 75
1 - 2 years 129
2 - 5 years 171
5 - 10 years 186
10 years or more 127

Stopped taking Bupropion

Duration Patients
Less than 1 month 278
1 - 6 months 328
6 months - 1 year 220
1 - 2 years 203
2 - 5 years 242
5 - 10 years 109
10 years or more 47
Adherence
Adherence Evaluations
Always 1601
Usually 319
Sometimes 45
Never taken as prescribed 87
Burden
Burden Evaluations
Very hard to take 69
Somewhat hard to take 127
A little hard to take 311
Not at all hard to take 1545
Cost per month
Cost per month Evaluations
$200+ 10
$100-199 25
$50-99 77
$25-49 157
< $25 1001
Not specified 782

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 65
Fluoxetine (Prozac) 55
Venlafaxine (Effexor XR) 52
Duloxetine (Cymbalta) 38
Citalopram (Celexa) 30

Show all 39 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 39
Sertraline (Zoloft) 31
Venlafaxine (Effexor XR) 24
Citalopram (Celexa) 19
Fluoxetine (Prozac) 19

Show all 40 treatments patients report switching to

Last updated:

186 patient evaluations for Bupropion

1,569 members have decided to share their profiles only with other members of PatientsLikeMe.

kcj1963
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kcj1963
Sex: M
Data Quality: 2 stars
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: mild
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See kcj1963's full Bupropion history

May 15, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    Mild (Dehydration)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Advice & Tips: not only did this help my attitude, but it increased my libido..:)
Cost: < $25 monthly

Apr 27, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    Mild (Dehydration)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
mountainlion
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mountainlion
Gender: F
Data Quality: 1 star
Depression: 0
Mania: 1
Emotional: 0
Anxiety: 1
Compulsion: 0
External Stress: Moderate
41 F
Function: Moderate
Distress: Low
I am: g
I have:
Bipolar Disorder

See mountainlion's full Bupropion history

Apr 27, 2012 (Started Aug 01, 2006)

  • Effectiveness
    Moderate (for Fatigue)
  • Side effects
    Mild (Weight loss)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg/24 hours Daily
Cost: < $25 monthly

  • 0 helpful marks
jiwhite
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jiwhite
Gender: F
Data Quality: 1 star
Depression: 0
Mania: 0
Emotional: 0
Anxiety: 1
Compulsion: 1
External Stress: Severe
48 F
Function: High
Distress: Low
I am: g
I have:
GAD

See jiwhite's full Bupropion history

Apr 8, 2012 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for Generalized Anxiety Disorder)
  • Effectiveness
    Major (for Major Depressive Disorder)
  • Side effects
    Mild (Morning nausea)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I use a pill organizer to keep track of whether or not I have taken my pills for the day and take them at the same time every day. I take pills at night when possible to minimize nausea.
Cost: $100-199 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 186 patient evaluations for Bupropion