What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,168 1,233
Depressed mood 1,572 771
Persistent depressive disorder (dysthymia) 376 313
Mild depression 151 64
Anxious mood 122 67

Show all 186 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 256
Moderate 370
Mild 593
None 1,080

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 103
Anxious mood 67
Weight gain 55
Insomnia 49
Headaches 46
Constipation 43

Show all 435 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 156
150 mg daily 128
100 mg daily 91
300 mg/24 hours daily 53
75 mg daily 51
450 mg daily 44
150 mg twice daily 38
100 mg twice daily 35
200 mg daily 22
150 mg/24 hours daily 19

See all 68 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 630
Side effects too severe 528
Doctor's advice 407
Other 268
Course of treatment ended 86
Expense 81
Personal research 71
Change in health plan coverage 40
See all 1535 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
1 - 6 months 75
6 months - 1 year 71
1 - 2 years 117
2 - 5 years 195
5 - 10 years 168
10 years or more 159

Stopped taking Bupropion

Duration Patients
Less than 1 month 323
1 - 6 months 351
6 months - 1 year 241
1 - 2 years 220
2 - 5 years 265
5 - 10 years 118
10 years or more 56
Adherence
Adherence Evaluations
Always 1798
Usually 345
Sometimes 52
Never taken as prescribed 104
Burden
Burden Evaluations
Very hard to take 77
Somewhat hard to take 144
A little hard to take 332
Not at all hard to take 1746
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 24
$50-99 84
$25-49 169
< $25 1114
Not specified 895

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 88
Fluoxetine (Prozac) 82
Venlafaxine (Effexor XR) 62
Citalopram (Celexa) 46
Duloxetine (Cymbalta) 45

Show all 54 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 44
Sertraline (Zoloft) 43
Venlafaxine (Effexor XR) 32
Citalopram (Celexa) 29
Fluoxetine (Prozac) 27

Show all 44 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

Jun 30, 2012 (Started Sep 01, 2008)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    Mild (nervousness)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 225 mg Daily
Advice & Tips: Doctor was reworking my meds.
Cost: < $25 monthly

  • 0 helpful marks

Jun 22, 2012 (Started Jul 20, 2009)

  • Effectiveness
    Moderate (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I take this in the AM when I get up. It does help me wake up (like caffeine, almost)
Cost: < $25 monthly

  • 0 helpful marks

May 15, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (dehydration)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Advice & Tips: not only did this help my attitude, but it increased my libido..:)
Cost: < $25 monthly

Apr 27, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (dehydration)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion