What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major depressive disorder 2,233 1,263
Depressed mood 1,595 783
Persistent depressive disorder (dysthymia) 388 317
Mild depression 152 65
Anxious mood 121 64

Show all 193 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe
263
Moderate
375
Mild
604
None
1,105

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 104
Anxious mood 70
Weight gain 55
Insomnia 50
Headaches 47
Constipation 43

Show all 441 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 179
150 mg daily 144
100 mg daily 77
300 mg/24 hours daily 62
450 mg daily 53
75 mg daily 47
150 mg twice daily 35
100 mg twice daily 30
200 mg daily 29
150 mg/24 hours daily 24

See all 72 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 644
Side effects too severe 540
Doctor's advice 416
Other 272
Course of treatment ended 88
Expense 82
Personal research 70
Change in health plan coverage 42
See all 1567 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 4
1 - 6 months 80
6 months - 1 year 76
1 - 2 years 110
2 - 5 years 201
5 - 10 years 186
10 years or more 170

Stopped taking Bupropion

Duration Patients
Less than 1 month 331
1 - 6 months 354
6 months - 1 year 245
1 - 2 years 225
2 - 5 years 272
5 - 10 years 120
10 years or more 58
Adherence
Adherence Evaluations
Always 1833
Usually 352
Sometimes 54
Never taken as prescribed 108
Burden
Burden Evaluations
Very hard to take 78
Somewhat hard to take 147
A little hard to take 338
Not at all hard to take 1784
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 24
$50-99 85
$25-49 174
< $25 1133
Not specified 918

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 92
Fluoxetine (Prozac) 84
Venlafaxine (Effexor XR) 70
Citalopram (Celexa) 50
Duloxetine (Cymbalta) 48

Show all 55 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 46
Sertraline (Zoloft) 45
Venlafaxine (Effexor XR) 35
Citalopram (Celexa) 31
Fluoxetine (Prozac) 28

Show all 46 treatments patients report switching to

Last updated:

184 patient evaluations for Bupropion

Jul 15, 2012 (Started Mar 09, 2009)

  • Effectiveness
    Can’t tell (for Treat my mood condition(s))
  • Effectiveness
    Can’t tell (for Other)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 450 mg Daily
Advice & Tips: helped with decreasing appetite. helped with increased sex drive. probably "fueling" mania
Cost: < $25 monthly

Aug 5, 2009 (Started Mar 09, 2009)

  • Effectiveness
    Major (for Other)
  • Effectiveness
    Major (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 450 mg Daily
Advice & Tips: for the most part i have little to no appetite when i'm on this drug and was able to loose over 40 pounds after going on it. i've since also gone on lamictal and lithium and have gained about 20 pounds. my daughters say i look much healthier now. i also like this drug because i don't feel it affects me sexually--i.e. it does not affect my sex drive when i am on it. i just have a $10 copay monthly. insurance pays the following.
Cost: $100-199 monthly

  • 5 helpful marks

Jun 30, 2012 (Started Sep 01, 2008)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    Mild (nervousness)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 225 mg Daily
Advice & Tips: Doctor was reworking my meds.
Cost: < $25 monthly

  • 0 helpful marks

Jun 22, 2012 (Started Jul 20, 2009)

  • Effectiveness
    Moderate (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I take this in the AM when I get up. It does help me wake up (like caffeine, almost)
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 184 patient evaluations for Bupropion