What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
major depressive disorder 2,051 1,182
Depressed mood 1,553 749
persistent depressive disorder (dysthymia) 361 300
mild depression 147 60
Anxious mood 119 63
bipolar disorder 105 90

Show all 213 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 248
Moderate 360
Mild 582
None 1,041

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 101
Anxious mood 63
Weight gain 53
Insomnia 49
Headaches 48
Constipation 41

Show all 429 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 171
150 mg daily 155
100 mg daily 111
300 mg/24 hours daily 69
75 mg daily 63
450 mg daily 54
100 mg twice daily 44
150 mg twice daily 41
200 mg daily 32
150 mg/24 hours daily 22

See all 82 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 604
Side effects too severe 509
Doctor's advice 392
Other 264
Course of treatment ended 83
Expense 80
Personal research 71
Change in health plan coverage 39
See all 1482 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 8
1 - 6 months 94
6 months - 1 year 120
1 - 2 years 157
2 - 5 years 203
5 - 10 years 196
10 years or more 164

Stopped taking Bupropion

Duration Patients
Less than 1 month 302
1 - 6 months 344
6 months - 1 year 237
1 - 2 years 212
2 - 5 years 258
5 - 10 years 114
10 years or more 55
Adherence
Adherence Evaluations
Always 1743
Usually 338
Sometimes 48
Never taken as prescribed 102
Burden
Burden Evaluations
Very hard to take 75
Somewhat hard to take 140
A little hard to take 330
Not at all hard to take 1686
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 84
$25-49 166
< $25 1081
Not specified 862

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 81
Fluoxetine (Prozac) 74
Venlafaxine (Effexor XR) 60
Citalopram (Celexa) 42
Duloxetine (Cymbalta) 42

Show all 53 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 44
Sertraline (Zoloft) 40
Venlafaxine (Effexor XR) 28
Citalopram (Celexa) 26
Fluoxetine (Prozac) 23

Show all 43 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

25yrRA
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25yrRA
Data Quality: 1 star
  • Gender: F
  • Age: 55
Condition: Rheumatoid Arthritis (RA) 20 additional condition(s)
Quality of life:
  • Mental: Mild
  • Physical: Mild
I am: g
I have:
Rheumatoid Arthritis (RA)

See 25yrRA's full Bupropion history

Jun 30, 2012 (Started Sep 01, 2008)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    Mild (Nervousness)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 225 mg Daily
Advice & Tips: Doctor was reworking my meds.
Cost: < $25 monthly

  • 0 helpful marks
isilzha
36592 thumb
isilzha
Gender: F
Data Quality: 0 stars
Pain: Most
Fatigue: Some
Sleep: All
Stiffness: Some
function: None
external_stress: Most
Stickman: most
Description:F43y
FM:13y Dx
I am: n
I have:
Fibromyalgia

See isilzha's full Bupropion history

Jun 22, 2012 (Started Jul 20, 2009)

  • Effectiveness
    Moderate (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: I take this in the AM when I get up. It does help me wake up (like caffeine, almost)
Cost: < $25 monthly

  • 0 helpful marks
kcj1963
43746 thumb
kcj1963
Sex: M
Data Quality: 2 stars
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: mild
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: n
I have:
MS

See kcj1963's full Bupropion history

May 15, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (Dehydration)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Advice & Tips: not only did this help my attitude, but it increased my libido..:)
Cost: < $25 monthly

Apr 27, 2012 (Started Oct 14, 2011)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (Dehydration)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion