What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Wellbutrin SR Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Major Depressive Disorder 1,535 844
Depressed mood 1,467 682
Persistent depressive disorder (dysthymia) 299 247
Mild Depression 131 49
Anxious mood 113 51
Bipolar Disorder 95 79

Show all 201 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 207
Moderate 282
Mild 472
None 813

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 83
Anxious mood 49
Insomnia 44
Constipation 36
Headaches 36
Weight gain 35

Show all 369 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
150 mg daily 78
300 mg/24 hours daily 73
300 mg daily 68
100 mg daily 45
150 mg/24 hours daily 31
75 mg daily 26
450 mg daily 25
150 mg twice daily 21
100 mg twice daily 20
200 mg daily 13

See all 52 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 504
Side effects too severe 425
Doctor's advice 344
Other 239
Course of treatment ended 75
Expense 75
Personal research 62
Change in health plan coverage 34
See all 1272 patients who’ve stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 2
1 - 6 months 32
6 months - 1 year 45
1 - 2 years 76
2 - 5 years 128
5 - 10 years 131
10 years or more 76

Stopped taking Bupropion

Duration Patients
Less than 1 month 241
1 - 6 months 313
6 months - 1 year 197
1 - 2 years 184
2 - 5 years 229
5 - 10 years 103
10 years or more 43
Adherence
Adherence Evaluations
Always 1394
Usually 283
Sometimes 41
Never taken as prescribed 56
Burden
Burden Evaluations
Very hard to take 58
Somewhat hard to take 103
A little hard to take 270
Not at all hard to take 1343
Cost per month
Cost per month Evaluations
$200+ 11
$100-199 21
$50-99 71
$25-49 147
< $25 862
Not specified 662

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 44
Venlafaxine (Effexor XR) 35
Fluoxetine (Prozac) 32
Duloxetine (Cymbalta) 27
Citalopram (Celexa) 19

Show all 35 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 26
Sertraline (Zoloft) 23
Venlafaxine (Effexor XR) 17
Bupropion (Wellbutrin XL) 13
Citalopram (Celexa) 12

Show all 33 treatments patients report switching to

Last updated:

183 patient evaluations for Bupropion

1,326 members have decided to share their profiles only with other members of PatientsLikeMe.

lilybet
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lilybet
Gender: F
Data Quality: 1 star
Depression: 1
Mania: 0
Emotional: 1
Anxiety: 1
Compulsion: 0
External Stress: Overwhelming
57 F
Function: Moderate
Distress: Low
I am: n
I have:
Major Depressive Disorder

See lilybet's full Bupropion history

Feb 23, 2012 (Started Mar 24, 2006)

  • Effectiveness
    Slight (for Reactive Depression)
  • Effectiveness
    Slight (for Major Depressive Disorder)
  • Effectiveness
    Slight (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 400 mg Daily
Advice & Tips: I really can't tell if Wellbutrin is helping me or not. The last several years have been so difficult for me that I'm not sure anything can help except time (and good psychotherapy!)
Cost: < $25 monthly

Sep 15, 2011 (Started Mar 24, 2006)

  • Effectiveness
    None (for Treat my mood condition(s))
  • Effectiveness
    None (for Reactive Depression)
  • Effectiveness
    None (for Major Depressive Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 400 mg Daily
Advice & Tips: I've been taking Wellbutrin since 2006. Since I've had several severe depression episodes since then, I really don't think it is helping at all.
Cost: < $25 monthly

Sep 9, 2008 (Started Mar 24, 2006)

  • Effectiveness
    Can’t tell (for Treat my mood condition(s))
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Well, I'm still depressed somewhat. But the reasons for it are more than biochemical, so I'm taking the med. Who knows what kind of shape I'd be in without it? (previously, bad!)
Cost: < $25 monthly

  • 1 helpful mark
Anna-Magdalena
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new ASD member
Data Quality: 1 star
65 years
Female
g
ATEC
  • Speech: 3
  • Sociability: 14
  • Sensory/Cognitive Awareness: 12
  • Health/Physical Behavior: 8
  • ATEC score: 37
I have:
Autism

See Anna-Magdalena's full Bupropion history

Feb 9, 2012 (Started Mar 29, 2011)

  • Effectiveness
    Can’t tell (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 150 mg/24 hours Daily

Sep 6, 2011 (Started Mar 29, 2011)

  • Effectiveness
    Can’t tell (for Bipolar I Disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 150 mg/24 hours Daily

  • 0 helpful marks
raehex
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raehex
Gender: F
Data Quality: 1 star
Pain: All
Fatigue: All
Sleep: All
Stiffness: All
function: Little
external_stress: Most
Stickman: all
Description:F25y
FM:9y Dx
I am: b
I have:
Fibromyalgia

See raehex's full Bupropion history

Feb 7, 2012 (Started Jul 01, 2011)

  • Effectiveness
    Major (for Treat my mood condition(s))
  • Side effects
    Mild (Nausea)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 150 mg/24 hours Daily
Advice & Tips: It helps you lose weight!
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 183 patient evaluations for Bupropion