What is Bupropion?

Category: Prescription Drugs

Most popular types: Wellbutrin XL Wellbutrin Bupropion XL Show all

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Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
major depressive disorder 2,093 1,199
Depressed mood 1,556 755
persistent depressive disorder (dysthymia) 365 304
mild depression 147 61
Anxious mood 120 64
bipolar disorder 105 91

Show all 213 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 249
Moderate 365
Mild 583
None 1,054

Commonly reported side effects and conditions associated with Bupropion

Side effect Patients
Dry mouth 101
Anxious mood 65
Weight gain 54
Insomnia 49
Headaches 47
Constipation 42

Show all 430 reported side effects

Dosages

Based on patients currently taking Bupropion

Dosage Patients
300 mg daily 179
150 mg daily 157
100 mg daily 103
75 mg daily 61
300 mg/24 hours daily 59
450 mg daily 55
150 mg twice daily 41
100 mg twice daily 36
200 mg daily 26
150 mg/24 hours daily 21

See all 84 dosages

Why patients stopped taking Bupropion

Multiple reasons could be selected

Reason Patients
Did not seem to work 609
Side effects too severe 512
Doctor's advice 396
Other 265
Course of treatment ended 85
Expense 80
Personal research 71
Change in health plan coverage 39
See all 1492 patients who've stopped taking Bupropion

Duration

Currently taking Bupropion

Duration Patients
Less than 1 month 17
1 - 6 months 78
6 months - 1 year 80
1 - 2 years 139
2 - 5 years 236
5 - 10 years 203
10 years or more 172

Stopped taking Bupropion

Duration Patients
Less than 1 month 308
1 - 6 months 346
6 months - 1 year 239
1 - 2 years 212
2 - 5 years 258
5 - 10 years 114
10 years or more 55
Adherence
Adherence Evaluations
Always 1760
Usually 340
Sometimes 49
Never taken as prescribed 102
Burden
Burden Evaluations
Very hard to take 75
Somewhat hard to take 141
A little hard to take 331
Not at all hard to take 1704
Cost per month
Cost per month Evaluations
$200+ 13
$100-199 25
$50-99 84
$25-49 168
< $25 1090
Not specified 871

What people switch to and from

Patients started taking Bupropion after stopping:

Treatment Patients
Sertraline (Zoloft) 85
Fluoxetine (Prozac) 77
Venlafaxine (Effexor XR) 62
Citalopram (Celexa) 44
Duloxetine (Cymbalta) 43

Show all 53 treatments patients report switching from

Patients stopped taking Bupropion and switched to:

Treatment Patients
Duloxetine (Cymbalta) 44
Sertraline (Zoloft) 41
Venlafaxine (Effexor XR) 30
Citalopram (Celexa) 26
Fluoxetine (Prozac) 24

Show all 44 treatments patients report switching to

Last updated:

185 patient evaluations for Bupropion

May 23, 2017 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

Jan 28, 2001 (Started Jul 01, 2001)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for Depressed mood)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for Depressed mood)
  • Effectiveness
    Moderate (for bipolar disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 75 mg Daily

Dec 4, 2010 (Started Mar 01, 2010)

  • Effectiveness
    Moderate (for Treat my mood condition(s))
  • Effectiveness
    Moderate (for bipolar disorder)
  • Effectiveness
    Major (for Depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily

  • 0 helpful marks

May 9, 2017 (Started Oct 02, 1996)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

Dec 4, 2010 (Started Oct 02, 1996)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 400 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 185 patient evaluations for Bupropion