RLS (Restless Legs Syndrome)

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What is RLS (Restless Legs Syndrome)?

Restless legs syndrome (RLS) is a neurological disorder characterized by an unpleasant sensation in the legs and an urge to move them for relief; usually occurs during or just prior to sleep. RLS sensations may also be felt in the arms or other parts of the body.

Common symptoms reported by people with RLS (Restless Legs Syndrome)

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

Treatments taken by people with RLS (Restless Legs Syndrome)

You’ve tried
Treatment name(s)
Type
How many have tried
Tried for
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Treatment name(s)

(Requip)
Type
Prescription Drug
How many have tried
112
Tried for
RLS (Restless Legs Syndrome) (111) Pain (1)
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Treatment name(s)

(Mirapex)
Type
Prescription Drug
How many have tried
82
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Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
75
Tried for
RLS (Restless Legs Syndrome) (39) Pain (35)
4 more
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Treatment name(s)

(Klonopin)
Type
Prescription Drug
How many have tried
51
Tried for
Anxious mood (39) RLS (Restless Legs Syndrome) (20)
1 more
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Treatment name(s)

(Desyrel)
Type
Prescription Drug
How many have tried
44
Tried for
Insomnia (42) RLS (Restless Legs Syndrome) (3)
3 more
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Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
39
Tried for
Pain (28) Insomnia (24)
3 more
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Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
37
Tried for
Pain (34) RLS (Restless Legs Syndrome) (4)
1 more
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Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
32
Tried for
Depressed mood (29) Pain (4)
1 more
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Treatment name(s)

(Lyrica)
Type
Prescription Drug
How many have tried
30
Tried for
Pain (26) RLS (Restless Legs Syndrome) (10)
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Treatment name(s)

(Norco)
Type
Prescription Drug
How many have tried
29
Tried for
Pain (29)

Data from patients with RLS (Restless Legs Syndrome), who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Compare treatments taken by people with RLS (Restless Legs Syndrome)

You’ve tried
Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Check to add this treatment to your profile
Treatment name(s)

(Requip)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (54 evaluations)
Side effects
Nausea Dizziness and feeling faint 27 more
Total evaluations
61
Tried for
RLS (Restless Legs Syndrome) (111) Pain (1)
Check to add this treatment to your profile
Treatment name(s)

(Mirapex)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (35 evaluations)
Side effects
Dizziness Drowsiness 24 more
Total evaluations
40
Check to add this treatment to your profile
Treatment name(s)

(Neurontin)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (17 evaluations)
Side effects
Sleepiness Weight gain 23 more
Total evaluations
46
Tried for
RLS (Restless Legs Syndrome) (39) Pain (35)
4 more
Check to add this treatment to your profile
Treatment name(s)

(Klonopin)
Perceived effectiveness
for Anxious mood (22 evaluations)
Side effects
Sleepiness Bipolar depressive episodes 12 more
Total evaluations
37
Tried for
Anxious mood (39) RLS (Restless Legs Syndrome) (20)
1 more
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Treatment name(s)

(Desyrel)
Perceived effectiveness
for Insomnia (25 evaluations)
Side effects
Drugged feeling Dry mouth 15 more
Total evaluations
26
Tried for
Insomnia (42) RLS (Restless Legs Syndrome) (3)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Elavil)
Perceived effectiveness
for Pain (28 evaluations)
Side effects
Dry mouth Dizziness 16 more
Total evaluations
36
Tried for
Pain (28) Insomnia (24)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Ultram)
Perceived effectiveness
for Pain (10 evaluations)
Side effects
Chronic constipation Dizziness 8 more
Total evaluations
13
Tried for
Pain (34) RLS (Restless Legs Syndrome) (4)
1 more
Check to add this treatment to your profile
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for Depressed mood (18 evaluations)
Side effects
Dry mouth Brain fog 7 more
Total evaluations
25
Tried for
Depressed mood (29) Pain (4)
1 more
Check to add this treatment to your profile
Treatment name(s)

(Lyrica)
Perceived effectiveness
for Pain (21 evaluations)
Side effects
Lightheadedness Anxious mood 37 more
Total evaluations
22
Tried for
Pain (26) RLS (Restless Legs Syndrome) (10)
Check to add this treatment to your profile
Treatment name(s)

(Norco)
Perceived effectiveness
for Pain (13 evaluations)
Side effects
Drowsiness Drug dependence 3 more
Total evaluations
13
Tried for
Pain (29)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with RLS (Restless Legs Syndrome), who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Who has RLS (Restless Legs Syndrome) on PatientsLikeMe?


Age
Age Proportion # of patients
<20 5
20s 94
30s 322
40s 708
50s 851
60s 530
70+ 173
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 309
20-29 years 263
30-39 years 382
40-49 years 370
50-59 years 176
60-69 years 34
70+ years 8

Sex

Distribution of sex

85% Female
15% Male

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 1,580
Not Diagnosed 251

These charts show data from Restless Legs patients who have completed their condition history
Last updated: