Restless legs syndrome

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What is restless legs syndrome?

Restless legs syndrome (RLS) is a neurological disorder characterized by an unpleasant sensation in the legs and an urge to move them for relief; usually occurs during or just prior to sleep. RLS sensations may also be felt in the arms or other parts of the body.

Common symptoms reported by people with restless legs syndrome

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
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Treatments taken by people with restless legs syndrome

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Requip)
Type
Prescription Drug
How many have tried
92
Tried for
restless legs syndrome (92)
Treatment name(s)

(Mirapex)
Type
Prescription Drug
How many have tried
75
Tried for
restless legs syndrome (75)
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
69
Tried for
restless legs syndrome (39) Pain (31)
4 more
Treatment name(s)

(Klonopin)
Type
Prescription Drug
How many have tried
48
Tried for
Anxious mood (38) restless legs syndrome (17)
1 more
Treatment name(s)

(Desyrel)
Type
Prescription Drug
How many have tried
35
Tried for
Insomnia (34) Anxious mood (1)
3 more
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
32
Tried for
Pain (29) restless legs syndrome (4)
1 more
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
31
Tried for
Depressed mood (28) Pain (4)
1 more
Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
30
Tried for
Pain (22) Insomnia (18)
1 more
Treatment name(s)

(Lyrica)
Type
Prescription Drug
How many have tried
28
Tried for
Pain (24) restless legs syndrome (10)
Treatment name(s)

(Norco)
Type
Prescription Drug
How many have tried
26
Tried for
Pain (26)

Data from patients with restless legs syndrome, who reported starting treatments within the last 5 years.
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Compare treatments taken by people with restless legs syndrome

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Requip)
Perceived effectiveness
for restless legs syndrome (47 evaluations)
Side effects
Nausea Dizziness and feeling faint 23 more
Total evaluations
53
Tried for
restless legs syndrome (91)
Treatment name(s)

(Mirapex)
Perceived effectiveness
for restless legs syndrome (37 evaluations)
Side effects
Dizziness Drowsiness 24 more
Total evaluations
40
Tried for
restless legs syndrome (75)
Treatment name(s)

(Neurontin)
Perceived effectiveness
for restless legs syndrome (18 evaluations)
Side effects
Sleepiness Weight gain 22 more
Total evaluations
47
Tried for
restless legs syndrome (39) Pain (31)
4 more
Treatment name(s)

(Klonopin)
Perceived effectiveness
for Anxious mood (24 evaluations)
Side effects
Sleepiness Bipolar depressive episodes 12 more
Total evaluations
37
Tried for
Anxious mood (38) restless legs syndrome (17)
1 more
Treatment name(s)

(Desyrel)
Perceived effectiveness
for Insomnia (19 evaluations)
Side effects
Dry mouth Acute hearing 10 more
Total evaluations
19
Tried for
Insomnia (34) Anxious mood (1)
3 more
Treatment name(s)

(Ultram)
Perceived effectiveness
for Pain (9 evaluations)
Side effects
Chronic constipation Dizziness 8 more
Total evaluations
12
Tried for
Pain (29) restless legs syndrome (4)
1 more
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for Depressed mood (18 evaluations)
Side effects
Dry mouth Brain fog 6 more
Total evaluations
21
Tried for
Depressed mood (28) Pain (4)
1 more
Treatment name(s)

(Elavil)
Perceived effectiveness
for Pain (23 evaluations)
Side effects
Dry mouth Dizziness 15 more
Total evaluations
31
Tried for
Pain (22) Insomnia (18)
1 more
Treatment name(s)

(Lyrica)
Perceived effectiveness
for Pain (23 evaluations)
Side effects
Anxious mood Fatigue 39 more
Total evaluations
25
Tried for
Pain (24) restless legs syndrome (10)
Treatment name(s)

(Norco)
Perceived effectiveness
for Pain (14 evaluations)
Side effects
Drowsiness Drug dependence 3 more
Total evaluations
14
Tried for
Pain (26)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with restless legs syndrome, who reported starting treatments within the last 5 years.
Last updated:

Who has restless legs syndrome on PatientsLikeMe?


Age
Age Proportion # of patients
<20 5
20s 94
30s 334
40s 727
50s 878
60s 565
70+ 184
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 312
20-29 years 270
30-39 years 386
40-49 years 376
50-59 years 178
60-69 years 37
70+ years 8

Sex

Distribution of sex

85% Female
15% Male

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 1,607
Not Diagnosed 255

These charts show data from restless legs syndrome (RLS) patients who have completed their condition history
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