RLS (Restless Legs Syndrome)

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What is RLS (Restless Legs Syndrome)?

Restless legs syndrome (RLS) is a neurological disorder characterized by an unpleasant sensation in the legs and an urge to move them for relief; usually occurs during or just prior to sleep. RLS sensations may also be felt in the arms or other parts of the body.

Common symptoms reported by people with RLS (Restless Legs Syndrome)

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

Treatments taken by people with RLS (Restless Legs Syndrome)

You’ve tried
Treatment name(s)
Type
How many have tried
Tried for
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Treatment name(s)

(Requip)
Type
Prescription Drug
How many have tried
110
Tried for
RLS (Restless Legs Syndrome) (109) Pain (1)
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Treatment name(s)

(Mirapex)
Type
Prescription Drug
How many have tried
82
Tried for
RLS (Restless Legs Syndrome) (82) Pain (1)
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Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
67
Tried for
RLS (Restless Legs Syndrome) (34) Pain (33)
4 more
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Treatment name(s)

(Klonopin)
Type
Prescription Drug
How many have tried
45
Tried for
Anxious mood (34) RLS (Restless Legs Syndrome) (17)
1 more
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Treatment name(s)

(Desyrel)
Type
Prescription Drug
How many have tried
45
Tried for
Insomnia (43) RLS (Restless Legs Syndrome) (2)
3 more
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Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
43
Tried for
Pain (30) Insomnia (27)
3 more
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Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
37
Tried for
Pain (35) RLS (Restless Legs Syndrome) (3)
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Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
34
Tried for
Depressed mood (30) Pain (4)
1 more
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Treatment name(s)

(Vicodin)
Type
Prescription Drug
How many have tried
34
Tried for
Pain (34)
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Treatment name(s)

(Flexeril)
Type
Prescription Drug
How many have tried
25
Tried for
Pain (21) RLS (Restless Legs Syndrome) (3)
1 more

Data from patients with RLS (Restless Legs Syndrome), who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Compare treatments taken by people with RLS (Restless Legs Syndrome)

You’ve tried
Treatment name(s)
Perceived effectiveness
Side effects
How many evaluations
Tried for
Check to add this treatment to your profile
Treatment name(s)

(Requip)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (53 evaluations)
Side effects
Nausea Dizziness and feeling faint 25 more
How many evaluations
57
Tried for
RLS (Restless Legs Syndrome) (109) Pain (1)
Check to add this treatment to your profile
Treatment name(s)

(Mirapex)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (32 evaluations)
Side effects
Drowsiness Blurry vision 21 more
How many evaluations
35
Tried for
RLS (Restless Legs Syndrome) (82) Pain (1)
Check to add this treatment to your profile
Treatment name(s)

(Neurontin)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (15 evaluations)
Side effects
Sleepiness Weight gain 19 more
How many evaluations
38
Tried for
RLS (Restless Legs Syndrome) (34) Pain (33)
4 more
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Treatment name(s)

(Klonopin)
Perceived effectiveness
for Anxious mood (19 evaluations)
Side effects
Sleepiness Bipolar depressive episodes 11 more
How many evaluations
33
Tried for
Anxious mood (34) RLS (Restless Legs Syndrome) (17)
1 more
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Treatment name(s)

(Desyrel)
Perceived effectiveness
for Insomnia (21 evaluations)
Side effects
Drugged feeling Anxious mood 11 more
How many evaluations
22
Tried for
Insomnia (43) RLS (Restless Legs Syndrome) (2)
3 more
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Treatment name(s)

(Elavil)
Perceived effectiveness
for Pain (32 evaluations)
Side effects
Dry mouth Dizziness 20 more
How many evaluations
43
Tried for
Pain (30) Insomnia (27)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Ultram)
Perceived effectiveness
for Pain (8 evaluations)
Side effects
Chronic constipation Dizziness 7 more
How many evaluations
11
Tried for
Pain (35) RLS (Restless Legs Syndrome) (3)
Check to add this treatment to your profile
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for Depressed mood (20 evaluations)
Side effects
Dry mouth Weight gain 9 more
How many evaluations
31
Tried for
Depressed mood (30) Pain (4)
1 more
Check to add this treatment to your profile
Treatment name(s)

(Vicodin)
Perceived effectiveness
for Pain (14 evaluations)
Side effects
Drowsiness Drug dependence 3 more
How many evaluations
14
Tried for
Pain (34)
Check to add this treatment to your profile
Treatment name(s)

(Flexeril)
Perceived effectiveness
for Pain (9 evaluations)
Side effects
Drowsiness Excessive daytime sleepiness (somnolence) 3 more
How many evaluations
12
Tried for
Pain (21) RLS (Restless Legs Syndrome) (3)
1 more

Data from patients with RLS (Restless Legs Syndrome), who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Who has RLS (Restless Legs Syndrome) on PatientsLikeMe?


Age
Age Proportion # of patients
<20 6
20s 87
30s 294
40s 644
50s 748
60s 453
70+ 143

Sex

Distribution of sex

84% Female
16% Male
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 297
20-29 years 248
30-39 years 356
40-49 years 340
50-59 years 159
60-69 years 30
70+ years 8

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 1,479
Not Diagnosed 244

These charts show data from Restless Legs patients who have completed their condition history
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