RLS (Restless Legs Syndrome)

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What is RLS (Restless Legs Syndrome)?

Restless legs syndrome (RLS) is a neurological disorder characterized by an unpleasant sensation in the legs and an urge to move them for relief; usually occurs during or just prior to sleep. RLS sensations may also be felt in the arms or other parts of the body.

Common symptoms reported by people with RLS (Restless Legs Syndrome)

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

Treatments taken by people with RLS (Restless Legs Syndrome)

You’ve tried
Treatment name(s)
Type
How many have tried
Tried for
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Treatment name(s)

(Requip)
Type
Prescription Drug
How many have tried
121
Tried for
RLS (Restless Legs Syndrome) (120) Pain (1)
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Treatment name(s)

(Mirapex)
Type
Prescription Drug
How many have tried
83
Tried for
RLS (Restless Legs Syndrome) (83) Insomnia (1)
1 more
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Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
61
Tried for
Pain (38) RLS (Restless Legs Syndrome) (27)
4 more
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Treatment name(s)

(Klonopin)
Type
Prescription Drug
How many have tried
55
Tried for
Anxious mood (35) RLS (Restless Legs Syndrome) (23)
2 more
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Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
49
Tried for
Pain (47) RLS (Restless Legs Syndrome) (3)
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Treatment name(s)

(Vicodin)
Type
Prescription Drug
How many have tried
45
Tried for
Pain (44) Anxious mood (1)
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Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
44
Tried for
Pain (31) Insomnia (28)
4 more
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Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
43
Tried for
Depressed mood (40) Pain (4)
3 more
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Treatment name(s)

(Desyrel)
Type
Prescription Drug
How many have tried
35
Tried for
Insomnia (34) Anxious mood (1)
3 more
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Treatment name(s)

(Lyrica)
Type
Prescription Drug
How many have tried
29
Tried for
Pain (26) RLS (Restless Legs Syndrome) (8)

Data from patients with RLS (Restless Legs Syndrome), who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Compare treatments taken by people with RLS (Restless Legs Syndrome)

You’ve tried
Treatment name(s)
Perceived effectiveness
Side effects
How many evaluations
Tried for
Check to add this treatment to your profile
Treatment name(s)

(Requip)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (61 evaluations)
Side effects
Nausea Dry cough 29 more
How many evaluations
64
Tried for
RLS (Restless Legs Syndrome) (120) Pain (1)
Check to add this treatment to your profile
Treatment name(s)

(Mirapex)
Perceived effectiveness
for RLS (Restless Legs Syndrome) (22 evaluations)
Side effects
Drowsiness Swelling in legs, feet and ankles 26 more
How many evaluations
25
Tried for
RLS (Restless Legs Syndrome) (83) Insomnia (1)
1 more
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Treatment name(s)

(Neurontin)
Perceived effectiveness
for Pain (15 evaluations)
Side effects
Sleepiness Altered state of consciousness 15 more
How many evaluations
26
Tried for
Pain (38) RLS (Restless Legs Syndrome) (27)
4 more
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Treatment name(s)

(Klonopin)
Perceived effectiveness
for Anxious mood (13 evaluations)
Side effects
Bipolar depressive episodes Bouts of Excessive Yawning 13 more
How many evaluations
26
Tried for
Anxious mood (35) RLS (Restless Legs Syndrome) (23)
2 more
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Treatment name(s)

(Ultram)
Perceived effectiveness
for Pain (11 evaluations)
Side effects
Headaches Chronic constipation 9 more
How many evaluations
16
Tried for
Pain (47) RLS (Restless Legs Syndrome) (3)
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Treatment name(s)

(Vicodin)
Perceived effectiveness
for Pain (19 evaluations)
Side effects
Addiction Constipation 4 more
How many evaluations
20
Tried for
Pain (44) Anxious mood (1)
Check to add this treatment to your profile
Treatment name(s)

(Elavil)
Perceived effectiveness
for Pain (24 evaluations)
Side effects
Dry mouth Rapid weight gain 17 more
How many evaluations
29
Tried for
Pain (31) Insomnia (28)
4 more
Check to add this treatment to your profile
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for Depressed mood (17 evaluations)
Side effects
Dry mouth Brain fog 10 more
How many evaluations
25
Tried for
Depressed mood (40) Pain (4)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Desyrel)
Perceived effectiveness
for Insomnia (23 evaluations)
Side effects
Drowsy in a.m. Drugged feeling 7 more
How many evaluations
23
Tried for
Insomnia (34) Anxious mood (1)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Lyrica)
Perceived effectiveness
for Pain (19 evaluations)
Side effects
Weight gain Lightheadedness 24 more
How many evaluations
23
Tried for
Pain (26) RLS (Restless Legs Syndrome) (8)

Data from patients with RLS (Restless Legs Syndrome), who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Who has RLS (Restless Legs Syndrome) on PatientsLikeMe?


Age
Age Proportion # of patients
<20 8
20s 90
30s 261
40s 561
50s 660
60s 311
70+ 99

Sex

Distribution of sex

85% Female
15% Male
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 252
20-29 years 212
30-39 years 313
40-49 years 299
50-59 years 131
60-69 years 25
70+ years 8

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 1,274
Not Diagnosed 217

These charts show data from Restless Legs patients who have completed their condition history
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