What is Zanaflex?

Category: Prescription Drugs

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Generic name: Tizanidine

Zanaflex® is a brand name for the drug tizanidine. It is used as a skeletal muscle relaxant for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Muscle spasms 291 88
Stiffness/Spasticity 281 108
Fibromyalgia 144 48
Muscle pain 51 19
Neck pain 29 4
Sleeplessness 29 10

Show all 100 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 26
Moderate 44
Mild 75
None 91

Commonly reported side effects and conditions associated with Zanaflex

Side effect Patients
Sleepiness 30
Drowsiness 21
Dry mouth 15
Dizziness 8
Dry eyes 8
Fatigue 8

Show all 59 reported side effects

Dosages

Based on patients currently taking Zanaflex

Dosage Patients
4 mg daily 15
8 mg daily 9
4 mg twice daily 8
4 mg three times daily 8
4mg as needed 7
2 mg daily 4
6 mg daily 3
12 mg daily 3
8 mg three times daily 3
2 mg three times daily 2

See all 22 dosages

Why patients stopped taking Zanaflex

Multiple reasons could be selected

Reason Patients
Did not seem to work 46
Side effects too severe 29
Other 25
Doctor's advice 24
Course of treatment ended 13
Expense 8
Personal research 5
Change in health plan coverage 3
See all 127 patients who’ve stopped taking Zanaflex

Duration

Currently taking Zanaflex

Duration Patients
1 - 6 months 8
6 months - 1 year 11
1 - 2 years 12
2 - 5 years 19
5 - 10 years 17
10 years or more 11

Stopped taking Zanaflex

Duration Patients
Less than 1 month 23
1 - 6 months 38
6 months - 1 year 18
1 - 2 years 23
2 - 5 years 12
5 - 10 years 12
10 years or more 1
Adherence
Adherence Evaluations
Always 161
Usually 44
Sometimes 25
Never taken as prescribed 6
Burden
Burden Evaluations
Very hard to take 17
Somewhat hard to take 12
A little hard to take 27
Not at all hard to take 180
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 0
$50-99 7
$25-49 12
< $25 144
Not specified 71

What people switch to and from

Patients started taking Zanaflex after stopping:

Treatment Patients
Cyclobenzaprine (Flexeril) 13
Baclofen (Mylan-Baclofen) 4
Carisoprodol (Soma) 4
Amitriptyline-Chlordiazepoxide (Limbitrol) 1
Dantrolene (Dantrium) 1

Show all 10 treatments patients report switching from

Patients stopped taking Zanaflex and switched to:

Treatment Patients
Baclofen (Mylan-Baclofen) 5
Cyclobenzaprine (Flexeril) 2
Diazepam (Valium) 2
Botulinum Toxin Type A (Botox) 1
Metaxalone (Skelaxin) 1

Show all 8 treatments patients report switching to

Last updated:

35 patient evaluations for Zanaflex

184 members have decided to share their profiles only with other members of PatientsLikeMe.

slowrambler
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slowrambler
Sex: M
Data Quality: 2 stars
Relapse: Moderate
Sensation: Severe
Overall: Mild
Cognition: none
Vision: none
Speech: none
Swallowing: none
Upper limb: none
Walking: severe
I am: b
I have:
MS

See slowrambler's full Zanaflex history

Mar 5, 2017 (Started Sep 10, 1999)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    Mild (Muscle fatigue, Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: Dry mouth, Muscle fatigue

Sep 7, 2012 (Started Sep 10, 1999)

  • Effectiveness
    Major (for Stiffness/Spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: Dry mouth, Muscle fatigue

Feb 9, 2009 (Started Sep 10, 1999)

  • Effectiveness
    Moderate (for Stiffness/Spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly
Side effects: Dry mouth, Muscle fatigue

Sep 7, 2008 (Started Sep 10, 1999)

  • Effectiveness
    Moderate (for Stiffness/Spasticity)
  • Side effects
    Mild (Muscle fatigue, Dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: This medication served me very well for several yrs. after I'd exhausted the use of Baclofen, which had become totally ineffective for me. This medication is not instant in terms of effectiveness. I had to "wean off" of the Baclofen & "ramp up" the dosage of Zanaflex & maintain a consistent level of this medication (in my bloodstream) before it became truly effective. After it became ineffective singularly, I began using it in combination with Keppra & I'm still realizing positive results using this regimen. I do experience some minor muscle fatigue & occasional dry mouth while using Zanaflex, however nothing close in terems of negative side effects as compared to Baclofen.
Cost: < $25 monthly
Side effects: Dry mouth, Muscle fatigue

  • 0 helpful marks
Srs2388
85822 thumb
Srs2388
Data Quality: 1 star
  • Gender: M
  • Age: 29y
  • Duration: ? yrs
Quality of life:
  • Mental: Severe
  • Physical: Severe
2 seizures
14 weeks ago
I am: vb
I have:
Epilepsy

See Srs2388's full Zanaflex history

Apr 13, 2016 (Started Apr 15, 2016)

  • Effectiveness
    Slight (for Stiffness/Spasticity)
  • Side effects
    Severe (Dry mouth, Drowsiness)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 4 mg Four times daily
Advice & Tips: If you have to be alert, avoid it. Keep a drink close.

  • 0 helpful marks
Keeper of the Flame
10493 thumb
Keeper of the Flame
Gender: F
Data Quality: 3 stars
Pain: All
Fatigue: Most
Sleep: Most
Stiffness: All
function: None
external_stress: Some
Stickman: all
Description:F59y
CFS:?y
FM:8y Dx
I am: g
I have:
Fibromyalgia

See Keeper of the Flame's full Zanaflex history

Mar 13, 2016 (Started Mar 01, 2016)

  • Effectiveness
    Moderate (for Muscle spasms)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 8 mg Twice daily
Advice & Tips: I really liked taking Flexeril but my insurance will no longer cover it as they say it causes falls. I will give the Zanaflex a try to see how it works for the next 6 months and then we will see and I will talk to my doctor if I don't think it is a good choice or I need an increase in the dosage as I don't feel anything from the dosage that I am currently taking.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 35 patient evaluations for Zanaflex