What is Zanaflex?

Category: Prescription Drugs

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Generic name: Tizanidine

Zanaflex® is a brand name for the drug tizanidine. It is used as a skeletal muscle relaxant for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Muscle spasms 284 84
Stiffness/Spasticity 275 101
Fibromyalgia 140 46
Muscle pain 51 19
Neck pain 29 4
Sleeplessness 29 10

Show all 100 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 25
Moderate 42
Mild 73
None 89

Commonly reported side effects and conditions associated with Zanaflex

Side effect Patients
Sleepiness 30
Drowsiness 20
Dry mouth 15
Dizziness 8
Dry eyes 8
Fatigue 8

Show all 58 reported side effects

Dosages

Based on patients currently taking Zanaflex

Dosage Patients
4 mg daily 14
8 mg daily 8
4mg as needed 6
2 mg daily 5
4 mg twice daily 5
4 mg three times daily 5
12 mg daily 4
8 mg three times daily 3
2 mg three times daily 2
6 mg daily 2

See all 21 dosages

Why patients stopped taking Zanaflex

Multiple reasons could be selected

Reason Patients
Did not seem to work 45
Side effects too severe 28
Other 25
Doctor's advice 23
Course of treatment ended 13
Expense 8
Personal research 5
Change in health plan coverage 3
See all 126 patients who’ve stopped taking Zanaflex

Duration

Currently taking Zanaflex

Duration Patients
Less than 1 month 1
1 - 6 months 2
6 months - 1 year 11
1 - 2 years 8
2 - 5 years 18
5 - 10 years 18
10 years or more 11

Stopped taking Zanaflex

Duration Patients
Less than 1 month 23
1 - 6 months 37
6 months - 1 year 18
1 - 2 years 23
2 - 5 years 12
5 - 10 years 12
10 years or more 1
Adherence
Adherence Evaluations
Always 155
Usually 43
Sometimes 25
Never taken as prescribed 6
Burden
Burden Evaluations
Very hard to take 17
Somewhat hard to take 11
A little hard to take 27
Not at all hard to take 174
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 0
$50-99 7
$25-49 12
< $25 139
Not specified 69

What people switch to and from

Patients started taking Zanaflex after stopping:

Treatment Patients
Cyclobenzaprine (Flexeril) 12
Baclofen (Mylan-Baclofen) 4
Carisoprodol (Soma) 4
Amitriptyline-Chlordiazepoxide (Limbitrol) 1
Dantrolene (Dantrium) 1

Show all 8 treatments patients report switching from

Patients stopped taking Zanaflex and switched to:

Treatment Patients
Baclofen (Mylan-Baclofen) 4
Cyclobenzaprine (Flexeril) 2
Botulinum Toxin Type A (Botox) 1
Diazepam (Valium) 1
Metaxalone (Skelaxin) 1

Show all 7 treatments patients report switching to

Last updated:

35 patient evaluations for Zanaflex

179 members have decided to share their profiles only with other members of PatientsLikeMe.

Srs2388
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Srs2388
Data Quality: 1 star
  • Gender: M
  • Age: 29y
  • Duration: ? yrs
Quality of life:
  • Mental: Severe
  • Physical: Severe
2 seizures
6 weeks ago
I am: vb
I have:
Epilepsy

See Srs2388's full Zanaflex history

Apr 13, 2016 (Started Apr 15, 2016)

  • Effectiveness
    Slight (for Stiffness/Spasticity)
  • Side effects
    Severe (Dry mouth, Drowsiness)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 4 mg Four times daily
Advice & Tips: If you have to be alert, avoid it. Keep a drink close.

  • 0 helpful marks
Keeper of the Flame
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Keeper of the Flame
Gender: F
Data Quality: 3 stars
Pain: Most
Fatigue: Most
Sleep: Most
Stiffness: All
function: Little
external_stress: Some
Stickman: most
Description:F59y
CFS:?y
FM:8y Dx
I am: g
I have:
Fibromyalgia

See Keeper of the Flame's full Zanaflex history

Mar 13, 2016 (Started Mar 01, 2016)

  • Effectiveness
    Moderate (for Muscle spasms)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 8 mg Twice daily
Advice & Tips: I really liked taking Flexeril but my insurance will no longer cover it as they say it causes falls. I will give the Zanaflex a try to see how it works for the next 6 months and then we will see and I will talk to my doctor if I don't think it is a good choice or I need an increase in the dosage as I don't feel anything from the dosage that I am currently taking.
Cost: < $25 monthly

  • 0 helpful marks
Wavewatcher
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Wavewatcher
Sex: F
Data Quality: 2 stars
Relapse: Severe
Sensation: Moderate
Overall: Moderate
Cognition: moderate
Vision: none
Speech: moderate
Swallowing: moderate
Upper limb: moderate
Walking: moderate
I am: g
I have:
MS

See Wavewatcher's full Zanaflex history

Sep 7, 2015 (Started Mar 12, 2005)

  • Effectiveness
    Major (for Muscle spasms)
  • Side effects
    Mild (Sleepiness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 12 mg Daily
Cost: < $25 monthly

Jul 28, 2010 (Started Mar 12, 2005)

  • Effectiveness
    Major (for Muscle spasms)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4 mg Daily
Advice & Tips: Medications are set up once a week for 3 times a day and this is only taken at night unless I am having very bad cramps. In that event I can take them PRN but I do not drive or cook as they make me sleepy.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 35 patient evaluations for Zanaflex