What is Imatinib?

Category: Prescription Drugs

Most popular types: Gleevec

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Imatinib is an antineoplastic agent which inhibits BCR-ABL tyrosine kinase, the abnormal gene product of the Philadelphia chromosome in chronic myeloid leukemia. It is also used for Ph+ acute lymphoblastic leukemia (ALL) and gastrointestinal stromal tumors (GIST).

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Chronic myeloid leukemia 20 12
Gastrointestinal stromal tumors 8 3
Mast cell activation syndrome 2 1
Giant cell tumor of the bone 1 0
Hypereosinophilic syndrome 1 1
Myeloproliferative disorder 1 1

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 2
Moderate 4
Mild 11
None 0

Commonly reported side effects and conditions associated with Imatinib

Side effect Patients
Diarrhea 7
Nausea 4
Elevated liver enzymes 2
Fatigue 2
Agitation with restlessness 1
Chronic diarrhea 1

Show all 25 reported side effects

Dosages

Based on patients currently taking Imatinib

Dosage Patients
400 mg daily 2

Why patients stopped taking Imatinib

Multiple reasons could be selected

Reason Patients
Side effects too severe 5
Doctor's advice 3
Did not seem to work 2
Other 1
See all 8 patients who've stopped taking Imatinib

Duration

Currently taking Imatinib

Duration Patients
6 months - 1 year 1
10 years or more 2

Stopped taking Imatinib

Duration Patients
Less than 1 month 2
1 - 6 months 1
6 months - 1 year 3
1 - 2 years 1
2 - 5 years 1
Adherence
Adherence Evaluations
Always 16
Usually 1
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations
Very hard to take 0
Somewhat hard to take 1
A little hard to take 4
Not at all hard to take 12
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 1
$50-99 0
$25-49 7
< $25 1
Not specified 6

What people switch to and from

Patients started taking Imatinib after stopping:

Treatment Patients
Hydroxychloroquine (Plaquenil) 1

Patients stopped taking Imatinib and switched to:

Treatment Patients
Dasatinib (Sprycel) 1
Sorafenib (Nexavar) 1
Last updated:
There are no evaluations for Imatinib.