What is Levothyroxine?

Category: Prescription Drugs

Most popular types: Synthroid Levoxyl Thyroxine Show all

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See also: Thyrolar-1

Levothyroxine is a synthetic form of the human hormone thyroxine. The drug is used to treat hypothyroidism (underactive thyroid), which can lead to weight gain, depression, and pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Hypothyroidism 3,082 1,002
Hashimoto's thyroiditis 521 206
General health 144 19
Thyroid cancer 105 22
Fatigue 35 18

Show all 84 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations
Severe 40
Moderate 98
Mild 117
None 1,033

Commonly reported side effects and conditions associated with Levothyroxine

Side effect Patients
Fatigue 31
Weight gain 28
Hair loss 26
Headaches 15
Heart palpitations 12
Nausea 12

Show all 151 reported side effects

Dosages

Based on patients currently taking Levothyroxine

Dosage Patients
50 mcg (0.05 mg) daily 73
0.075 mg daily 66
0.1 mg daily 63
0.05 mg daily 54
100 mcg (0.1 mg) daily 52
0.125 mg daily 50
0.025 mg daily 42
75 mcg (0.075 mg) daily 38
0.088 mg daily 37
0.112 mg daily 29

See all 115 dosages

Why patients stopped taking Levothyroxine

Multiple reasons could be selected

Reason Patients
Did not seem to work 96
Doctor's advice 79
Other 69
Side effects too severe 51
Personal research 42
Change in health plan coverage 19
Course of treatment ended 18
Expense 12
See all 291 patients who've stopped taking Levothyroxine

Duration

Currently taking Levothyroxine

Duration Patients
1 - 6 months 25
6 months - 1 year 17
1 - 2 years 51
2 - 5 years 145
5 - 10 years 241
10 years or more 422

Stopped taking Levothyroxine

Duration Patients
Less than 1 month 25
1 - 6 months 54
6 months - 1 year 40
1 - 2 years 34
2 - 5 years 50
5 - 10 years 45
10 years or more 54
Adherence
Adherence Evaluations
Always 1108
Usually 145
Sometimes 8
Never taken as prescribed 27
Burden
Burden Evaluations
Very hard to take 22
Somewhat hard to take 88
A little hard to take 191
Not at all hard to take 987
Cost per month
Cost per month Evaluations
$200+ 2
$100-199 2
$50-99 13
$25-49 57
< $25 776
Not specified 438

What people switch to and from

Patients started taking Levothyroxine after stopping:

Treatment Patients
Desiccated thyroid (Armour Thyroid) 25
Levothyroxine (Synthroid) 9
Liothyronine (T3) (Cytomel) 6
Methimazole (Tapazole) 2
Antidepressants 1

Show all 10 treatments patients report switching from

Patients stopped taking Levothyroxine and switched to:

Treatment Patients
Desiccated thyroid (Armour Thyroid) 55
Levothyroxine (Synthroid) 8
Liothyronine (T3) (Cytomel) 7
Amitriptyline (Elavil) 1
Duloxetine (Cymbalta) 1

Show all 10 treatments patients report switching to

Last updated:

95 patient evaluations for Levothyroxine

Jul 8, 2018 (Started Jul 01, 1993)

  • Effectiveness
    Major (for Hashimoto's thyroiditis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily
Cost: < $25 monthly

  • 0 helpful marks

May 26, 2018 (Started Feb 06, 2009)

  • Effectiveness
    Moderate (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg (0.05 mg) Daily
Advice & Tips: Everything seems to be going fine.
Cost: < $25 monthly

Aug 11, 2015 (Started Feb 06, 2009)

  • Effectiveness
    Moderate (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg (0.05 mg) Daily
Advice & Tips: HAVEN'T NOTICED ANYTHING DIFFERENT.
Cost: < $25 monthly

Aug 16, 2014 (Started Feb 06, 2009)

  • Effectiveness
    Moderate (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg (0.05 mg) Daily
Advice & Tips: I have just started to have some changes in my blood work concerning my thyroid; but nothing major.

Jul 14, 2012 (Started Feb 06, 2009)

  • Effectiveness
    Moderate (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mcg (0.05 mg) Daily

  • 0 helpful marks

Apr 29, 2018 (Started May 18, 2007)

  • Effectiveness
    Major (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 137 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 95 patient evaluations for Levothyroxine